Protein profile

KP13_04148

Tellurium resistance protein terD

Genome: KpKP13

Gene: terD AHE47498.1 Structure source: AlphaFold + ColabFold UniProt A0A0J4WRJ1
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Amino acids 192
Annotations 1
Features 7
PDB binders 0
Druggability 0.07

Overview

Basic information about this protein and its source genome.

Accession
KP13_04148
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
terD AHE47498.1
Status
annotated
Amino acids
192
Structure source
AlphaFold + ColabFold
GO
GO:0046690 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
68.254
DEG E-value
6.3e-98
Localization
Cytoplasmic
ColabFold pLDDT
82.97

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.07
Structure A0A0J4WRJ1
Pocket Pocket 1
P2Rank 0.196
Structure A0A0J4WRJ1
Pocket Pocket 1
ColabFold model
FPocket 0.126 · Pocket 3
P2Rank 0.037 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 167 / 4744 genomes with a hit
Normalized 0.035

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0046690 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
19 186 Gene3D G3DSA:2.60.60.30 sav2460 like domains
1 187 Pfam PF02342 TerD domain
1 187 InterPro IPR003325 TerD domain
20 188 CDD cd06974 TerD_like
20 188 InterPro IPR003325 TerD domain
1 191 PANTHER PTHR32097 CAMP-BINDING PROTEIN 1-RELATED
19 186 FunFam G3DSA:2.60.60.30:FF:000001 Tellurium resistance protein TerD

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0J4WRJ1
AlphaFold — — full sequence — Viewing
ColabFold KP13_04148
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 3.02 0.099
2 1.4 0.017