Protein profile

KP13_04150

Tellurium resistance protein terF

Genome: KpKP13

Gene: AHE47500.1 Structure source: AlphaFold + ColabFold UniProt A0A7U2D7D8
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Amino acids 413
Annotations 1
Features 16
PDB binders 0
Druggability 0.28

Overview

Basic information about this protein and its source genome.

Accession
KP13_04150
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE47500.1
Status
annotated
Amino acids
413
Structure source
AlphaFold + ColabFold
GO
GO:0046690 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
91.11

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.28
Structure A0A7U2D7D8
Pocket Pocket 20
P2Rank 0.095
Structure A0A7U2D7D8
Pocket Pocket 1
ColabFold model
FPocket 0.264 · Pocket 3
P2Rank 0.088 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 9 / 4744 genomes with a hit
Normalized 0.002

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0046690 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.

Sequence Features

Domain/signature hits from InterPro and related databases.

16 records
Show feature table
Start End DB Term Name
11 162 CDD cd06974 TerD_like
11 162 InterPro IPR003325 TerD domain
1 161 Pfam PF02342 TerD domain
1 161 InterPro IPR003325 TerD domain
212 389 SUPERFAMILY SSF53300 vWA-like
212 389 InterPro IPR036465 von Willebrand factor A-like domain superfamily
2 277 PANTHER PTHR32097 CAMP-BINDING PROTEIN 1-RELATED
212 413 Pfam PF10138 vWA found in TerF C terminus
212 413 InterPro IPR019303 vWA found in TerF C terminus
14 159 Gene3D G3DSA:2.60.60.30 sav2460 like domains
213 396 ProSiteProfiles PS50234 VWFA domain profile.
213 396 InterPro IPR002035 von Willebrand factor, type A
211 391 SMART SM00327 VWA_4
211 391 InterPro IPR002035 von Willebrand factor, type A
200 400 Gene3D G3DSA:3.40.50.410 von Willebrand factor, type A domain
200 400 InterPro IPR036465 von Willebrand factor A-like domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A7U2D7D8
AlphaFold — — full sequence — Viewing
ColabFold KP13_04150
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
20 0.28
4 0.264

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 3.01 0.098
2 0.85 0.003