Proteins

Genome: KpATCC43816

Description: Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome

Search, filter, and prioritize proteins.

Export view
5 proteins

Scoring formula None

Sorted by Druggability (descending)

Applied filters EC Number: 3.1.3.2

Search query No active search

Rows per page 25

Rows
Active criteria 1
EC Number: 3.1.3.2 ×
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
1 VK055_4616 haloacid dehalogenase-like hydrolase family protein AlphaFold + ColabFold
3.1.3.27
GO:0046872Binding to a metal ion. GO:0008962Catalysis of the reaction: phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate.
0.665 No Hit 0.0% —
2 VK055_4636 inositol monophosphatase, putative mRNA turnover protein suhB AlphaFold + ColabFold
3.1.3.25
GO:0008934Catalysis of the reaction: 1D-myo-inositol 1-phosphate + H2O = myo-inositol + phosphate. GO:0046854The chemical reactions and pathways resulting in the formation of phosphatidylinositol phosphate. GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. +69 total
0.463 Hit 44.1% 1.44e-13
3 VK055_1253 acid phosphatase pho AlphaFold + ColabFold
3.1.3.2
GO:0030288The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall. GO:0003993Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum.
0.344 No Hit 0.0% —
4 VK055_1904 inositol monophosphatase family protein AlphaFold + ColabFold
3.1.3.25
GO:0008934Catalysis of the reaction: 1D-myo-inositol 1-phosphate + H2O = myo-inositol + phosphate. GO:0046872Binding to a metal ion. GO:0006020The chemical reactions and pathways involving inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms. +25 total
0.242 Hit 35.0% 2.64e-06
5 VK055_3363 sugar phosphatase yidA AlphaFold + ColabFold
3.1.3.23
GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0000287Binding to a magnesium (Mg) ion. +14 total
0.202 No Hit 0.0% —
Page 1 of 1 · 5 total proteins