Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

Search, filter, and prioritize proteins.

Export view
3 / 5842 proteins
View settings

Scoring formula None

Sorted by Druggability (P2Rank preferred) (descending)

Applied filters EC Number: 2.7.7.8

Search query No active search

Rows per page 25

Rows
Active criteria 1
EC Number: 2.7.7.8 ×
# Protein Description Gene Structure EC GO Metabolism Druggability (P2Rank) P2RANK ligandability score for the best pocket in the experimental structure (0–1). Higher values indicate higher predicted ligandability. Available only for genomes analyzed with the curated pipeline. Druggability (FPocket) FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
1 KP13_04289 Sulfur carrier protein moaD adenylyltransferase moeB AlphaFold DB model + ColabFold model
2.7.7.80
GO:0008641Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond. GO:0006777The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +47 total
No map 0.899 0.13 Hit 47.9% 2.09e-07
2 KP13_31491 Polyribonucleotide nucleotidyltransferase pnp AlphaFold DB model + ColabFold model
2.7.7.8
GO:0004654Catalysis of the reaction: RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate. GO:0003676Binding to a nucleic acid. GO:0006396Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. +58 total
No map 0.878 0.435 Hit 44.6% 2.39e-08
3 KP13_00785 Putative ribosome maturation factor rimN rimN AlphaFold DB model + ColabFold model
2.7.7.87
GO:0002949The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base). GO:0003725Binding to double-stranded RNA. GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. +47 total
No map 0.399 0.598 Hit 27.6% 6.36e-07
Page 1 of 1 · 3 total proteins