Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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Applied filters EC Number: 3.1.3.7

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EC Number: 3.1.3.7 ×
# Protein Description Gene Structure EC GO Metabolism Druggability (P2Rank) P2RANK ligandability score for the best pocket in the experimental structure (0–1). Higher values indicate higher predicted ligandability. Available only for genomes analyzed with the curated pipeline. Druggability (FPocket) FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
1 KP13_03336 Alpha-ribazole phosphatase cobC AlphaFold DB model + ColabFold model
3.1.3.73
GO:0043755Catalysis of the reaction: alpha-ribazole 5'-phosphate + H2O = alpha-ribazole + phosphate. GO:0003824Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. GO:0016868Catalysis of the transfer of a phosphate group from one position to another within a single molecule. +69 total
No map 0.890 0.52 Hit 28.7% 1.11e-10
2 KP13_11760 3'(2'),5'-bisphosphate nucleotidase cysQ cysQ AlphaFold DB model + ColabFold model
3.1.3.7
GO:0046854The chemical reactions and pathways resulting in the formation of phosphatidylinositol phosphate. GO:0000287Binding to a magnesium (Mg) ion. GO:0006790The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. +47 total
No map 0.857 0.559 Hit 30.5% 3.30e-11
3 KP13_03363 Enolase-phosphatase E1 mtnC AlphaFold DB model + ColabFold model
3.1.3.77
GO:0043874Catalysis of the reactions:5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate. GO:0000287Binding to a magnesium (Mg) ion. GO:0019509OBSOLETE. The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine. +25 total
No map 0.786 0.83 Hit 42.9% 3.32e-40
4 KP13_05487 phosphoglycerate mutase family protein AlphaFold DB model + ColabFold model
3.1.3.73
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0043755Catalysis of the reaction: alpha-ribazole 5'-phosphate + H2O = alpha-ribazole + phosphate.
No map 0.656 0.367 Hit 32.0% 3.33e-07
Page 1 of 1 · 4 total proteins