Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

Search, filter, and prioritize proteins.

Export view
6 proteins

Scoring formula None

Sorted by Druggability (descending)

Applied filters EC Number: 3.6.4.13

Search query No active search

Rows per page 25

Rows
Active criteria 1
EC Number: 3.6.4.13 ×
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
1 KP13_04385 ATP-independent RNA helicase dbpA dbpA AlphaFold + ColabFold
3.6.4.13
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0003676Binding to a nucleic acid. GO:0003724Unwinding of an RNA helix, driven by ATP hydrolysis. +58 total
0.797 Hit 50.5% 6.29e-20
2 KP13_04321 ATP-dependent RNA helicase rhlE rhlE AlphaFold + ColabFold
3.6.4.13
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0003676Binding to a nucleic acid. GO:0042255The aggregation, arrangement and bonding together of the mature ribosome and of its subunits. +47 total
0.668 Hit 52.5% 1.77e-12
3 KP13_01093 Cold-shock DEAD box protein A deaD AlphaFold + ColabFold
3.6.4.13
GO:0070417Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. GO:0003676Binding to a nucleic acid. GO:0003724Unwinding of an RNA helix, driven by ATP hydrolysis. +912 total
0.46 Hit 50.8% 6.23e-12
4 KP13_04982 ATP-dependent RNA helicase hrpA hrpA AlphaFold + ColabFold
3.6.4.13
GO:0004386Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix. GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. GO:0003676Binding to a nucleic acid. +47 total
0.393 Hit 51.2% 1.23e-07
5 KP13_00803 ATP-dependent RNA helicase srmB srmB AlphaFold + ColabFold
3.6.4.13
GO:0000027The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit. GO:0003676Binding to a nucleic acid. GO:0003724Unwinding of an RNA helix, driven by ATP hydrolysis. +36 total
0.181 Hit 56.5% 2.92e-14
6 KP13_01685 ATP-dependent RNA helicase rhlB rhlB AlphaFold + ColabFold
3.6.4.13
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0003676Binding to a nucleic acid. GO:0003724Unwinding of an RNA helix, driven by ATP hydrolysis. +47 total
0.105 Hit 54.5% 1.13e-17
Page 1 of 1 · 6 total proteins