Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 / 5842 proteins

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Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
5176 KP13_06213 Isocitrate dehydrogenase [NADP] AlphaFold + ColabFold –
GO:0006099A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle. GO:0004450Catalysis of the reaction: isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.
0.573 No Hit 0.0% —
5177 KP13_06281 hypothetical protein ColabFold – – 0.601 No Hit 0.0% —
5178 KP13_06286 hypothetical protein AlphaFold + ColabFold – – 0.241 No Hit 0.0% —
5179 KP13_06613 hypothetical protein AlphaFold + ColabFold – – 0.235 No Hit 0.0% —
5180 KP13_06614 hypothetical protein ColabFold – – 0.451 No Hit 0.0% —
5181 KP13_06615 hypothetical protein AlphaFold + ColabFold – – 0.454 No Hit 0.0% —
5182 KP13_06616 hypothetical protein AlphaFold + ColabFold – – 0.544 No Hit 0.0% —
5183 KP13_06618 hypothetical protein ColabFold – – 0.526 No Hit 0.0% —
5184 KP13_06619 hypothetical protein AlphaFold + ColabFold – – 0.171 No Hit 0.0% —
5185 KP13_06620 hypothetical protein AlphaFold + ColabFold – – 0.566 No Hit 0.0% —
5186 KP13_06624 hypothetical protein AlphaFold + ColabFold –
GO:0009061The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor.
0.586 No Hit 0.0% —
5187 KP13_06627 hypothetical protein AlphaFold + ColabFold – – 0.322 No Hit 0.0% —
5188 KP13_06630 hypothetical protein AlphaFold + ColabFold – – 0.774 No Hit 0.0% —
5189 KP13_06631 phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase AlphaFold + ColabFold –
GO:0003824Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
0.772 No Hit 0.0% —
5190 KP13_06632 hypothetical protein AlphaFold + ColabFold – – 0.975 No Hit 0.0% —
5191 KP13_06633 hypothetical protein ColabFold – – 0.718 No Hit 0.0% —
5192 KP13_06634 hypothetical protein AlphaFold + ColabFold – – 0.3 No Hit 0.0% —
5193 KP13_06635 hypothetical protein AlphaFold + ColabFold – – 0.334 No Hit 0.0% —
5194 KP13_06636 hypothetical protein AlphaFold + ColabFold – – 0.4 No Hit 0.0% —
5195 KP13_06637 hypothetical protein AlphaFold + ColabFold – – 0.229 No Hit 0.0% —
5196 KP13_06638 hypothetical protein AlphaFold + ColabFold – – 0.051 No Hit 0.0% —
5197 KP13_06639 Lambda repressor-like, DNA-binding protein AlphaFold + ColabFold –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.313 No Hit 0.0% —
5198 KP13_06640 hypothetical protein AlphaFold + ColabFold – – 0.805 No Hit 0.0% —
5199 KP13_06641 DNA-binding protein HU-beta AlphaFold + ColabFold –
GO:0030527The action of a molecule that contributes to the structural integrity of chromatin. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +69 total
0.574 No Hit 0.0% —
5200 KP13_06647 hypothetical protein ColabFold – – 0.451 No Hit 0.0% —
Page of 234 · 5842 total proteins