Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

Search, filter, and prioritize proteins.

Export view
5842 proteins

Scoring formula None

Sorted by Human E-value (ascending)

Applied filters No active filters

Search query No active search

Rows per page 25

Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
5526 KP13_31828 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase murE AlphaFold + ColabFold
6.3.2.13
GO:0008360Any process that modulates the surface configuration of a cell. GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0009058A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. +710 total
0.742 No Hit 0.0% —
5527 KP13_31829 hypothetical protein AlphaFold + ColabFold – – 0.482 No Hit 0.0% —
5528 KP13_31830 Type 3 fimbrial subunit MrkA mrkA AlphaFold + ColabFold –
GO:0007155The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. GO:0009289A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter. GO:0043709The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species.
0.041 No Hit 0.0% —
5529 KP13_31831 Type 3 fimbrial subunit MrkB mrkB AlphaFold + ColabFold –
GO:0061077OBSOLETE. The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone. GO:0043711A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pilus, a short filamentous structure on a bacterial cell, flagella-like in structure and generally present in many copies. GO:0030288The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall. +14 total
0.225 No Hit 0.0% —
5530 KP13_31832 Sucrose-6-phosphate hydrolase cscA AlphaFold + ColabFold
3.2.1.26
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0005975The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. GO:0004553Catalysis of the hydrolysis of any O-glycosyl bond. +25 total
0.304 No Hit 0.0% —
5531 KP13_31834 aspartate racemase AlphaFold + ColabFold –
GO:0047661Catalysis of the reaction: an L-amino acid = a D-amino acid. GO:0016855Catalysis of a reaction that alters the configuration of one or more chiral centers in an amino acid. GO:0036361OBSOLETE. Catalysis of the interconversion of the two enantiomers of a chiral amino acid or amino acid derivative. +14 total
0.55 No Hit 0.0% —
5532 KP13_31835 HTH-type transcriptional regulator AscG AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. +14 total
0.783 No Hit 0.0% —
5533 KP13_31838 putative transposase AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
0.228 No Hit 0.0% —
5534 KP13_31839 hypothetical protein AlphaFold + ColabFold – – 0.78 No Hit 0.0% —
5535 KP13_31840 hypothetical protein AlphaFold + ColabFold – – 0.344 No Hit 0.0% —
5536 KP13_31841 hypothetical protein AlphaFold + ColabFold – – 0.38 No Hit 0.0% —
5537 KP13_31842 hypothetical protein AlphaFold + ColabFold – – 0.687 No Hit 0.0% —
5538 KP13_31843 hypothetical protein AlphaFold + ColabFold – – 0.551 No Hit 0.0% —
5539 KP13_31844 hypothetical protein AlphaFold + ColabFold – – 0.41 No Hit 0.0% —
5540 KP13_31847 putative acyl-CoA N-acyltransferase Experimental + ColabFold –
GO:0016747Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
0.557 No Hit 0.0% —
5541 KP13_31848 putative RecF protein AlphaFold + ColabFold –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. GO:0000731Synthesis of DNA that proceeds from the broken 3' single-strand DNA end and uses the homologous intact duplex as the template. +14 total
0.331 No Hit 0.0% —
5542 KP13_31849 Beta-lactamase SHV 110 Experimental + ColabFold –
GO:0008800Catalysis of the reaction: a beta-lactam + H2O = a substituted beta-amino acid. GO:0017001The chemical reactions and pathways resulting in the breakdown of antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms. GO:0046677Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms. +14 total
0.996 No Hit 0.0% —
5543 KP13_31850 hypothetical protein ColabFold – – 0.491 No Hit 0.0% —
5544 KP13_31851 hypothetical protein AlphaFold + ColabFold – – 0.305 No Hit 0.0% —
5545 KP13_31852 hypothetical protein AlphaFold + ColabFold – – 0.312 No Hit 0.0% —
5546 KP13_31853 hypothetical protein AlphaFold + ColabFold – – 0.414 No Hit 0.0% —
5547 KP13_31854 putative dithiobiotin synthetase AlphaFold + ColabFold
6.3.3.3
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0009102The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid. GO:0000287Binding to a magnesium (Mg) ion. +36 total
0.127 No Hit 0.0% —
5548 KP13_31855 GCN5-like N-acetyltransferase AlphaFold + ColabFold –
GO:0016747Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
0.212 No Hit 0.0% —
5549 KP13_31857 hypothetical protein ColabFold – – 0.219 No Hit 0.0% —
5550 KP13_31860 hypothetical protein AlphaFold + ColabFold – – 0.133 No Hit 0.0% —
Page of 234 · 5842 total proteins