Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 proteins

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# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
5751 KP13_32148 hypothetical protein ColabFold – – 0.56 No Hit 0.0% —
5752 KP13_32149 hypothetical protein ColabFold – – 0.918 No Hit 0.0% —
5753 KP13_32150 Transcriptional regulator AcoK AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0005515Binding to a protein. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.899 No Hit 0.0% —
5754 KP13_32151 hypothetical protein ColabFold – – 0.443 No Hit 0.0% —
5755 KP13_32152 Quinoprotein glucose dehydrogenase gcd AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0016614Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. GO:0030288The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall. +36 total
1 No Hit 0.0% —
5756 KP13_32153 putative lipoprotein AlphaFold + ColabFold – – 0.303 No Hit 0.0% —
5757 KP13_32155 hypothetical protein ColabFold – – 0.693 No Hit 0.0% —
5758 KP13_32158 hypothetical protein ColabFold – – 0.536 No Hit 0.0% —
5759 KP13_32159 tRNA/rRNA methyltransferase LasT AlphaFold + ColabFold
2.1.1.200
GO:0008173Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule. GO:0006396Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. GO:0003723Binding to an RNA molecule or a portion thereof. +47 total
0.508 No Hit 0.0% —
5760 KP13_32161 hypothetical protein ColabFold – – 0.244 No Hit 0.0% —
5761 KP13_32162 p-hydroxybenzoate hydroxylase pobA AlphaFold + ColabFold
1.14.13.2
GO:0043639The chemical reactions and pathways resulting in the breakdown of benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid. GO:0071949Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. GO:0018659Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = protocatechuate + NADP+ + H2O. +14 total
0.611 No Hit 0.0% —
5762 KP13_32163 maltose-inducible porin Maltoporin AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0034219The process in which a carbohydrate is transported across a membrane. GO:0015288Enables the transfer of substances, sized less than 1000 Da, from one side of a membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.
0.632 No Hit 0.0% —
5763 KP13_32164 transposase insH for insertion sequence element IS5H AlphaFold + ColabFold –
GO:0004803Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element. GO:0006313A type of transposition in which a transposable element (transposon) is moved to another part of a genome, either by a cut-and-paste mechanism or a replicative mechanism. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.5 No Hit 0.0% —
5764 KP13_32165 Spermidine/putrescine ABC transporter, permease protein ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
0.464 No Hit 0.0% —
5765 KP13_32167 Insertion element IS3 family ColabFold – – 0.344 No Hit 0.0% —
5766 KP13_32168 hypothetical protein AlphaFold + ColabFold – – 0.266 No Hit 0.0% —
5767 KP13_32171 hypothetical protein ColabFold – – 0.603 No Hit 0.0% —
5768 KP13_32172 hypothetical protein ColabFold – – 0.04 No Hit 0.0% —
5769 KP13_32173 hypothetical protein ColabFold – – 0.373 No Hit 0.0% —
5770 KP13_32174 PRD domain-containing protein ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
0.763 No Hit 0.0% —
5771 KP13_32175 Peptidase PmbA pmbA AlphaFold + ColabFold –
GO:0006508The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. GO:0008237Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
0.435 No Hit 0.0% —
5772 KP13_32176 hypothetical protein ColabFold – – No pocket No Hit 0.0% —
5773 KP13_32177 hypothetical protein ColabFold – – No pocket No Hit 0.0% —
5774 KP13_32178 hypothetical protein ColabFold – – 0.6 No Hit 0.0% —
5775 KP13_32179 ABC transporter periplasmic-binding protein AlphaFold + ColabFold –
GO:0030313An envelope that surrounds a bacterial cell and includes the cytoplasmic membrane and everything external, encompassing the periplasmic space, cell wall, and outer membrane if present. GO:0030246Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
0.102 No Hit 0.0% —
Page of 234 · 5842 total proteins