Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 / 5842 proteins

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Rows
# Protein Description Gene Structure EC GO Metabolism Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
601 KP13_06718 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.46 No Hit 0.0% —
602 KP13_06711 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.667 No Hit 0.0% —
603 KP13_06708 putative inner membrane protein AlphaFold DB model + ColabFold model – – No map 0.59 No Hit 0.0% —
604 KP13_06704 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.141 No Hit 0.0% —
605 KP13_06703 Carbepenem-hydrolyzing beta-lactamase KPC2 Experimental + ColabFold model
3.5.2.6
GO:0008800Catalysis of the reaction: a beta-lactam + H2O = a substituted beta-amino acid. GO:0017001The chemical reactions and pathways resulting in the breakdown of antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms. GO:0046677Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms. +25 total
No map 0.994 No Hit 0.0% —
606 KP13_06702 putative transposase AlphaFold DB model + ColabFold model –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0004803Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element. GO:0006313A type of transposition in which a transposable element (transposon) is moved to another part of a genome, either by a cut-and-paste mechanism or a replicative mechanism.
No map 0.157 No Hit 0.0% —
607 KP13_06701 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.317 No Hit 0.0% —
608 KP13_06700 Antirestriction protein klcA klcA AlphaFold DB model + ColabFold model – – No map 0.275 No Hit 0.0% —
609 KP13_06699 putative replication protein AlphaFold DB model + ColabFold model –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0043565Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
No map 0.39 No Hit 0.0% —
610 KP13_06698 transposase for insertion sequence-like element IS431mec AlphaFold DB model + ColabFold model –
GO:0003676Binding to a nucleic acid. GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
No map 0.584 No Hit 0.0% —
611 KP13_06696 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.395 No Hit 0.0% —
612 KP13_06695 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.755 No Hit 0.0% —
613 KP13_06694 conjugal transfer TraG-like protein AlphaFold DB model + ColabFold model – – No map 0.6 No Hit 0.0% —
614 KP13_06693 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.628 No Hit 0.0% —
615 KP13_06690 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.07 No Hit 0.0% —
616 KP13_06689 hypothetical protein ColabFold model – – No map 0.542 No Hit 0.0% —
617 KP13_06688 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.822 No Hit 0.0% —
618 KP13_06687 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.505 No Hit 0.0% —
619 KP13_06686 Phosphatidylinositol-specific phospholipase C ColabFold model – – No map 0.677 No Hit 0.0% —
620 KP13_06685 DSBA-like thioredoxin domain-containing protein AlphaFold DB model + ColabFold model –
GO:0016853Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5. GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
No map 0.827 No Hit 0.0% —
621 KP13_06681 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.998 No Hit 0.0% —
622 KP13_06680 hypothetical protein ColabFold model – – No map 0.659 No Hit 0.0% —
623 KP13_06679 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.362 No Hit 0.0% —
624 KP13_06678 hypothetical protein ColabFold model – – No map 0.403 No Hit 0.0% —
625 KP13_06677 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.796 No Hit 0.0% —
Page of 234 · 5842 total proteins