Metabolic network

VK055_2294

acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta

Network centrality 0.02063 top 92.7%
Chokepoint Yes

Attractive metabolic target: catalyzes a consuming chokepoint reaction in Citrate cycle (TCA cycle), more central than 92.7% of genes in this genome.

Pathways

KEGG pathways this gene's reaction(s) belong to.

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

Click a node in the network above, or a row in the table below, to inspect it here.

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EC
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Pathway
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Genes
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Role
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Isoenzymes
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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

RXN-22436

EC - · RXN-22436 · not reversible · no isoenzyme backup

coenzyme A an [acetoin dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine
acetyl-CoA an [acetoin dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine

RXN-22435

EC - · RXN-22435 · not reversible · no isoenzyme backup

acetoin an [acetoin dehydrogenase E2 protein] N6-lipoyl-L-lysine
an [acetoin dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine acetaldehyde

RXN-22437

EC - · RXN-22437 · not reversible · 3 isoenzymes

an [acetoin dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine NAD+
an [acetoin dehydrogenase E2 protein] N6-lipoyl-L-lysine NADH H+

RXN-9718

EC 2.3.1.190 · RXN-9718 · not reversible · no isoenzyme backup

acetoin coenzyme A NAD+
acetaldehyde acetyl-CoA NADH H+

RXN-12508

EC - · RXN-12508 · not reversible · 2 isoenzymes

Consuming chokepoint
2-(alpha-hydroxyethyl)thiamine diphosphate a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine
a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine thiamine diphosphate

RXN-12583

EC - · RXN-12583 · not reversible · 2 isoenzymes

Producing & consuming chokepoint
H+ pyruvate thiamine diphosphate
2-(alpha-hydroxyethyl)thiamine diphosphate CO2

Imported from KpATCC43816.sbml · 2026-07-09