2.3.1.168-RXN
EC 2.3.1.168 · R02662 · 2.3.1.168-RXN · reversible
KEGG:map00785
Lipoic acid metabolism
KpATCC43816 - Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Reactions
8
Proteins
10
Metabolites
27
Chokepoints
4
Pathway map
Reaction-to-metabolite flow reconstructed from the imported SBML participants.
Chokepoint reaction
Metabolite
⇌ Reversible reaction
Currency metabolites hidden
Computing layout…
Connected pathways
Other pathways in this genome that share reactions with this one.
Reaction table
Catalyzed reactions, mapped genes, and SBML substrates/products.
a [glycine-cleavage complex H protein] N6-[(R)-lipoyl]-L-lysine
glycine
H+
⇌
a [glycine-cleavage complex H protein] N6-aminomethyldihydrolipoyl-L-lysine
CO2
a [glycine-cleavage complex H protein] N6-aminomethyldihydrolipoyl-L-lysine
a tetrahydrofolate
⇌
a 5,10-methylenetetrahydrofolate
a [glycine-cleavage complex H protein] N6-dihydrolipoyl-L-lysine
ammonium
a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine
coenzyme A
→
a [pyruvate dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine
acetyl-CoA
a [2-oxoglutarate dehydrogenase E2 protein] N6-S-succinyldihydrolipoyl-L-lysine
coenzyme A
→
a [2-oxoglutarate dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine
succinyl-CoA
2-(alpha-hydroxyethyl)thiamine diphosphate
a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine
→
a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine
thiamine diphosphate
pyruvate
thiamine diphosphate
H+
→
2-(alpha-hydroxyethyl)thiamine diphosphate
CO2
(R)-lipoate
ATP
H+
→
[(R)-lipoyl]adenylate
diphosphate