Metabolic network

VK055_2591

purine nucleoside phosphorylase

Back to protein
Network centrality 0.13817 top 98.2%
Chokepoint Yes

Attractive metabolic target: catalyzes a consuming chokepoint reaction in Cysteine and methionine metabolism, no isoenzyme backup detected, more central than 98.2% of genes in this genome, no human homolog detected.

Pathways

KEGG pathways this gene's reaction(s) belong to.

Cysteine and methionine metabolism Purine metabolism

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

Click a node in the network above, or a row in the table below, to inspect it here.

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EC
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Pathway
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Genes
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Role
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Isoenzymes
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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

RXN0-5199

EC 2.4.2.1, 2.4.2.15 · RXN0-5199 · reversible · no isoenzyme backup

guanosine phosphate
⇌
guanine alpha-D-ribose-1-phosphate

RXN-12241

EC 2.4.2.44 · RXN-12241 · not reversible · no isoenzyme backup

Consuming chokepoint
S-methyl-5'-thioinosine phosphate
→
hypoxanthine S-methyl-5-thio-alpha-D-ribose 1-phosphate

Imported from KpATCC43816.sbml · 2026-07-09