KEGG:map00270

Cysteine and methionine metabolism

KpATCC43816 - Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome

All pathways Protein ranking
Reactions 31
Proteins 29
Metabolites 66
Chokepoints 11

Pathway map

Reaction-to-metabolite flow reconstructed from the imported SBML participants.

Chokepoint reaction Metabolite ⇌ Reversible reaction Currency metabolites hidden
Computing layout…

Connected pathways

Other pathways in this genome that share reactions with this one.

MODEL Unassigned metabolic reactions 69 shared KEGG Purine metabolism 12 shared KEGG Citrate cycle (TCA cycle) 4 shared KEGG Arginine and proline metabolism 4 shared KEGG Valine, leucine and isoleucine degradation 3 shared KEGG Glycine, serine and threonine metabolism 2 shared KEGG Taurine and hypotaurine metabolism 2 shared KEGG Pyrimidine metabolism 2 shared KEGG Sulfur metabolism 2 shared KEGG Glyoxylate and dicarboxylate metabolism 2 shared KEGG Methane metabolism 2 shared KEGG Lysine biosynthesis 2 shared KEGG Alanine, aspartate and glutamate metabolism 2 shared KEGG Benzoate degradation 2 shared KEGG Phenylalanine metabolism 1 shared

Reaction table

Catalyzed reactions, mapped genes, and SBML substrates/products.

3.1.3.77-RXN

EC 3.1.3.77 · R07395 · 3.1.3.77-RXN · not reversible

5-(methylsulfanyl)-2,3-dioxopentyl 1-phosphate H2O
→
1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one H+ phosphate
VK055_1889

5.3.1.23-RXN

EC 5.3.1.23 · R04420 · 5.3.1.23-RXN · reversible

S-methyl-5-thio-alpha-D-ribose 1-phosphate
⇌
S-methyl-5-thio-D-ribulose 1-phosphate
VK055_1907

CYSTEINE-AMINOTRANSFERASE-RXN

EC 2.6.1.3 · R00895 · CYSTEINE-AMINOTRANSFERASE-RXN · reversible

2-oxoglutarate L-cysteine
⇌
2-oxo-3-sulfanylpropanoate L-glutamate
No mapped protein

HOMSUCTRAN-RXN

EC 2.3.1.46 · R01777 · HOMSUCTRAN-RXN · not reversible

L-homoserine succinyl-CoA
→
O-succinyl-L-homoserine coenzyme A
VK055_3080

PGLYCDEHYDROG-RXN

EC 1.1.1.95 · R01513 · PGLYCDEHYDROG-RXN · reversible

3-phospho-D-glycerate NAD+
⇌
3-phosphooxypyruvate H+ NADH
No mapped protein

R146-RXN

EC 1.13.11.53 · R07363 · R146-RXN · not reversible

1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one dioxygen
→
3-(methylsulfanyl)propanoate carbon monoxide formate H+
VK055_1890

R147-RXN

EC 1.13.11.54 · R07364 · R147-RXN · not reversible

1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one dioxygen
→
4-(methylsulfanyl)-2-oxobutanoate formate H+
VK055_1890

R82-RXN

EC 5.3.2.5 · R07393 · R82-RXN · not reversible

producing
5-(methylsulfanyl)-2,3-dioxopentyl 1-phosphate
→
2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl 1-phosphate H+
VK055_1889

R83-RXN

EC 3.1.3.87 · R07394 · R83-RXN · not reversible

consuming
2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl 1-phosphate H2O
→
1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one phosphate
VK055_1889

RXN-10035

EC 3.5.4.31 · R09660 · RXN-10035 · not reversible

S-methyl-5'-thioadenosine H+ H2O
→
S-methyl-5'-thioinosine ammonium
No mapped protein

RXN-12241

EC 2.4.2.44 · R09668 · RXN-12241 · not reversible

consuming
S-methyl-5'-thioinosine phosphate
→
S-methyl-5-thio-alpha-D-ribose 1-phosphate hypoxanthine
VK055_2591

RXN-9384

EC 2.5.1.48 · R01288 · RXN-9384 · reversible

O-succinyl-L-homoserine hydrogen sulfide
⇌
L-homocysteine succinate H+
VK055_3243

SAMDECARB-RXN

EC 4.1.1.50 · R00178 · SAMDECARB-RXN · not reversible

producing
S-adenosyl-L-methionine H+
→
S-adenosyl 3-(methylsulfanyl)propylamine CO2
VK055_2443

SPERMIDINESYN-RXN

EC 2.5.1.16 · R01920 · SPERMIDINESYN-RXN · not reversible

both
S-adenosyl 3-(methylsulfanyl)propylamine putrescine
→
S-methyl-5'-thioadenosine spermidine H+
VK055_2442

SULFOCYS-RXN

EC 2.5.1.144 · R03132 · SULFOCYS-RXN · reversible

O-acetyl-L-serine thiosulfate
⇌
S-sulfo-L-cysteine acetate H+
VK055_4743