Metabolic network

VK055_4789

acetyl-CoA C-acyltransferase FadI

Back to protein
Network centrality 0.1176 top 97.8%
Chokepoint Yes

Attractive metabolic target: catalyzes a producing chokepoint reaction in Benzoate degradation, more central than 97.8% of genes in this genome.

Pathways

KEGG pathways this gene's reaction(s) belong to.

Benzoate degradation Butanoate metabolism Ethylbenzene degradation Fatty acid degradation Fatty acid elongation Glyoxylate and dicarboxylate metabolism Lysine degradation Other carbon fixation pathways Pyruvate metabolism Terpenoid backbone biosynthesis Tryptophan metabolism Valine, leucine and isoleucine degradation

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

Click a node in the network above, or a row in the table below, to inspect it here.

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EC
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Pathway
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Genes
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Role
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Isoenzymes
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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

RXN-17782

EC 2.3.1.16 · RXN-17782 · reversible · 3 isoenzymes

(5Z)-tetradecenoyl-CoA acetyl-CoA
⇌
3-oxo-(7Z)-hexadecenoyl-CoA coenzyme A

RXN-12565

EC 2.3.1.16, 2.3.1.9 · RXN-12565 · reversible · 3 isoenzymes

butanoyl-CoA acetyl-CoA
⇌
3-oxohexanoyl-CoA coenzyme A

RXN-13617

EC 2.3.1.16, 2.3.1.9 · RXN-13617 · reversible · 3 isoenzymes

octanoyl-CoA acetyl-CoA
⇌
3-oxodecanoyl-CoA coenzyme A

RXN-2006

EC 2.3.1.16 · RXN-2006 · reversible · 2 isoenzymes

benzoyl-CoA acetyl-CoA
⇌
3-oxo-3-phenylpropanoyl-CoA coenzyme A

RXN-20150

EC - · RXN-20150 · not reversible · 2 isoenzymes

Producing chokepoint
a 3-oxoacyl-CoA a [protein]-L-cysteine
→
a [protein] S-acyl-L-cysteine acetyl-CoA

RXN-20152

EC - · RXN-20152 · not reversible · 2 isoenzymes

Consuming chokepoint
a [protein] S-acyl-L-cysteine coenzyme A
→
a [protein]-L-cysteine an acyl-CoA

RXN-20154

EC - · RXN-20154 · reversible · 3 isoenzymes

acetyl-CoA a [protein]-L-cysteine
⇌
a [protein] S-acetyl-L-cysteine coenzyme A

RXN-20155

EC - · RXN-20155 · reversible · 3 isoenzymes

a [protein] S-acetyl-L-cysteine acetyl-CoA
⇌
acetoacetyl-CoA a [protein]-L-cysteine

RXN-14274

EC 2.3.1.16, 2.3.1.9 · RXN-14274 · reversible · 3 isoenzymes

decanoyl-CoA acetyl-CoA
⇌
3-oxododecanoyl-CoA coenzyme A

RXN-14277

EC 2.3.1.16, 2.3.1.9 · RXN-14277 · reversible · 3 isoenzymes

hexanoyl-CoA acetyl-CoA
⇌
3-oxooctanoyl-CoA coenzyme A

RXN-14394

EC 2.3.1.16 · RXN-14394 · reversible · 3 isoenzymes

(3Z)-dodec-3-enoyl-CoA acetyl-CoA
⇌
3-oxo-(5Z)-tetradecenoyl-CoA coenzyme A

RXN-17778

EC 2.3.1.16 · RXN-17778 · reversible · 3 isoenzymes

(7Z)-hexadecenoyl-CoA acetyl-CoA
⇌
3-oxo-(9Z)-octadecenoyl-CoA coenzyme A

Imported from KpATCC43816.sbml · 2026-07-09