MODEL:unassigned

Unassigned metabolic reactions

KpATCC43816 - Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome

All pathways Protein ranking
Reactions 1290
Proteins 542
Metabolites 1656
Chokepoints 125

Pathway map

Reaction-to-metabolite flow reconstructed from the imported SBML participants.

Chokepoint reaction Metabolite ⇌ Reversible reaction Currency metabolites hidden
Computing layout…

Graph capped for readability; 1245 additional reactions are listed below.

Connected pathways

Other pathways in this genome that share reactions with this one.

KEGG Purine metabolism 209 shared KEGG Pyrimidine metabolism 91 shared KEGG Glycolysis / Gluconeogenesis 91 shared KEGG Cysteine and methionine metabolism 69 shared KEGG Glycine, serine and threonine metabolism 65 shared KEGG Pentose phosphate pathway 65 shared KEGG Citrate cycle (TCA cycle) 53 shared KEGG Valine, leucine and isoleucine degradation 52 shared KEGG Fructose and mannose metabolism 50 shared KEGG Amino sugar and nucleotide sugar metabolism 48 shared KEGG Porphyrin metabolism 42 shared KEGG Alanine, aspartate and glutamate metabolism 41 shared KEGG Pentose and glucuronate interconversions 40 shared KEGG Phenylalanine, tyrosine and tryptophan biosynthesis 40 shared KEGG Arginine biosynthesis 40 shared KEGG Nicotinate and nicotinamide metabolism 39 shared KEGG Phenylalanine metabolism 38 shared KEGG Glyoxylate and dicarboxylate metabolism 37 shared KEGG Pyruvate metabolism 34 shared KEGG Glycerophospholipid metabolism 34 shared KEGG Starch and sucrose metabolism 32 shared KEGG Propanoate metabolism 31 shared KEGG Glycerolipid metabolism 29 shared KEGG Galactose metabolism 24 shared KEGG Fatty acid biosynthesis 23 shared KEGG Benzoate degradation 23 shared KEGG Biosynthesis of various nucleotide sugars 23 shared KEGG Arginine and proline metabolism 23 shared KEGG Fatty acid degradation 22 shared KEGG Thiamine metabolism 21 shared KEGG Valine, leucine and isoleucine biosynthesis 20 shared KEGG Folate biosynthesis 19 shared KEGG Riboflavin metabolism 19 shared KEGG Glutathione metabolism 18 shared KEGG Sulfur metabolism 17 shared KEGG Lysine biosynthesis 17 shared KEGG Peptidoglycan biosynthesis 16 shared KEGG Lipopolysaccharide biosynthesis 15 shared KEGG Terpenoid backbone biosynthesis 14 shared KEGG Aminoacyl-tRNA biosynthesis 14 shared KEGG Nitrogen metabolism 13 shared KEGG Histidine metabolism 13 shared KEGG Phosphonate and phosphinate metabolism 12 shared KEGG Methane metabolism 12 shared KEGG Pantothenate and CoA biosynthesis 12 shared KEGG Tyrosine metabolism 12 shared KEGG D-Amino acid metabolism 12 shared KEGG Selenocompound metabolism 11 shared KEGG Taurine and hypotaurine metabolism 10 shared KEGG Ubiquinone and other terpenoid-quinone biosynthesis 10 shared KEGG Fatty acid elongation 10 shared KEGG One carbon pool by folate 10 shared KEGG Carbon fixation by Calvin cycle 10 shared KEGG Lysine degradation 9 shared KEGG Butanoate metabolism 7 shared KEGG Aminobenzoate degradation 7 shared KEGG beta-Alanine metabolism 6 shared KEGG Glucosinolate biosynthesis 5 shared KEGG Biotin metabolism 5 shared KEGG Vitamin B6 metabolism 5 shared KEGG Carbapenem biosynthesis 5 shared KEGG Toluene degradation 3 shared KEGG Inositol phosphate metabolism 3 shared KEGG Lipoic acid metabolism 3 shared KEGG Tropane, piperidine and pyridine alkaloid biosynthesis 3 shared KEGG Zeatin biosynthesis 2 shared KEGG Mycolic acid biosynthesis 2 shared KEGG Monobactam biosynthesis 2 shared KEGG Tryptophan metabolism 1 shared KEGG Ethylbenzene degradation 1 shared KEGG Phenylpropanoid biosynthesis 1 shared KEGG Biosynthesis of siderophore group nonribosomal peptides 1 shared KEGG Ascorbate and aldarate metabolism 1 shared KEGG Atrazine degradation 1 shared KEGG Fluorobenzoate degradation 1 shared

Reaction table

Catalyzed reactions, mapped genes, and SBML substrates/products.

1.2.1.25-RXN

EC 1.2.1.25 · R01210 · 1.2.1.25-RXN · not reversible

3-methyl-2-oxobutanoate NAD+ coenzyme A
→
isobutanoyl-CoA CO2 NADH
No mapped protein

1.2.2.3-RXN

EC 1.17.2.3 · R03215 · 1.2.2.3-RXN · not reversible

a reduced cytochrome c-553 CO2 H+
→
an oxidized cytochrome c-553 formate
No mapped protein

1.2.4.4-RXN

EC 1.2.4.4 · R01701 · 1.2.4.4-RXN · reversible

3-methyl-2-oxobutanoate a [BCAA dehydrogenase E2 protein] N6-lipoyl-L-lysine H+
⇌
an [apo BCAA dehydrogenase E2 protein] N6-S-[2-methylpropanoyl]dihydrolipoyl-L-lysine CO2
No mapped protein

1.5.1.34-RXN

EC 1.5.1.34 · R07355 · 1.5.1.34-RXN · not reversible

6,7-dihydrobiopterin NAD(P)H H+
→
5,6,7,8-tetrahydrobiopterin NAD(P)+
VK055_1987

1.8.1.4-RXN

EC 1.8.1.4 · R01698 · 1.8.1.4-RXN · not reversible

a [lipoyl-carrier protein]-N6-[(R)-dihydrolipoyl]-L-lysine NAD+
→
a [lipoyl-carrier protein]-N6-[(R)-lipoyl]-L-lysine H+ NADH
VK055_2296 VK055_2450

1PFRUCTPHOSN-RXN

EC 2.7.1.56 · R02071 · 1PFRUCTPHOSN-RXN · not reversible

beta-D-fructofuranose 1-phosphate ATP
→
beta-D-fructofuranose 1,6-bisphosphate ADP H+
VK055_4923

2.1.1.64-RXN

EC 2.1.1.64 · R07235 · 2.1.1.64-RXN · not reversible

3-demethylubiquinol-9 S-adenosyl-L-methionine
→
S-adenosyl-L-homocysteine ubiquinol-9 H+
VK055_4874

2.1.1.77-RXN

EC 2.1.1.77 · R04190 · 2.1.1.77-RXN · not reversible

S-adenosyl-L-methionine a [protein]-L-beta-isoaspartate
→
S-adenosyl-L-homocysteine a protein L-beta-isoaspartate alpha-methyl ester
VK055_4411

2.3.1.118-RXN

EC 2.3.1.118 · R08386 · 2.3.1.118-RXN · not reversible

acetyl-CoA an N-hydroxy-arylamine
→
an N-acetoxyarylamine coenzyme A
VK055_0599

2.3.1.128-RXN

EC 2.3.1.266 · R04316 · 2.3.1.128-RXN · not reversible

acetyl-CoA an N-terminal L-alanyl-[bS18 protein of 30S ribosome]
→
an N-terminal N-acetyl-L-alanyl-[bS18 protein of 30S ribosome] H+ coenzyme A
VK055_1388 VK055_2602

2.3.1.49-RXN

EC 2.3.1.49 · 2.3.1.49-RXN · not reversible

S-acetyl phosphopantetheine a holo [citrate lyase acyl-carrier protein]
→
4'-phosphopantetheine an acetyl-holo [citrate lyase acyl-carrier protein]
No mapped protein

2.4.1.36-RXN

EC 2.4.1.36 · R02168 · 2.4.1.36-RXN · not reversible

D-glucopyranose 6-phosphate GDP-alpha-D-glucose
→
alpha,alpha-trehalose 6-phosphate GDP H+
VK055_0055

2.5.1.39-RXN

EC 2.5.1.39 · R07273 · 2.5.1.39-RXN · not reversible

4-hydroxybenzoate all-trans-nonaprenyl diphosphate
→
4-hydroxy-3-(all-trans-nonaprenyl)benzoate diphosphate
VK055_3045

2.7.10.1-RXN

EC 2.7.10.2 · R02584 · 2.7.10.1-RXN · not reversible

a [protein]-L-tyrosine ATP
→
a [protein]-L-tyrosine phosphate ADP H+
VK055_5017

2.7.3.9-RXN

EC 2.7.3.9 · R02628 · 2.7.3.9-RXN · not reversible

an [HPr]-L-histidine phosphoenolpyruvate
→
an [HPr protein]-Npi-phospho-L-histidine pyruvate
VK055_4287

2.7.7.61-RXN

EC 2.7.7.61 · 2.7.7.61-RXN · not reversible

2'-(5''-triphospho-alpha-D-ribosyl)-3'-dephospho-CoA an apo [citrate-lyase acyl-carrier protein]
→
a holo [citrate lyase acyl-carrier protein] diphosphate
VK055_2518

2-OCTAPRENYL-6-METHOXYPHENOL-HYDROX-RXN

EC 1.14.13.- · 2-OCTAPRENYL-6-METHOXYPHENOL-HYDROX-RXN · not reversible

2-methoxy-6-(all-trans-octaprenyl)phenol H+ NADPH dioxygen
→
2-methoxy-6-(all trans-octaprenyl)benzene-1,4-diol H2O NADP+
VK055_4140

2OXOGLUTDECARB-RXN

EC 1.2.4.2 · 2OXOGLUTDECARB-RXN · not reversible

both
2-oxoglutarate a [2-oxoglutarate dehydrogenase E2 protein] N6-lipoyl-L-lysine H+
→
a [2-oxoglutarate dehydrogenase E2 protein] N6-S-succinyldihydrolipoyl-L-lysine CO2
VK055_1796

3.2.1.26-RXN

EC 3.2.1.26 · 3.2.1.26-RXN · not reversible

consuming
sucrose 6G-phosphate H2O
→
beta-D-fructofuranose beta-D-glucose 6-phosphate
VK055_2036 VK055_4263

3.2.1.47-RXN

EC 3.2.1.22 · 3.2.1.47-RXN · not reversible

a globotriosylceramide H2O
→
D-galactopyranose a lactosylceramide
VK055_3274

3.2.1.52-RXN

EC 3.2.1.52 · 3.2.1.52-RXN · not reversible

an N-acetyl-beta-D-hexosaminide H2O
→
an N-acetyl-beta-D-hexosamine an alcohol
VK055_1361

3.5.1.81-RXN

EC 3.5.1.81 · R02192 · 3.5.1.81-RXN · not reversible

an N-acylated-D-amino acid H2O
→
a D-amino acid a carboxylate
VK055_2644

3.5.1.88-RXN

EC 3.5.1.88 · R05635 · 3.5.1.88-RXN · not reversible

a [protein] N-terminal-formyl-L-methionine H2O
→
an N-terminal L-methionyl-[protein] formate
VK055_3786

5.1.3.9-RXN

EC 5.1.3.9 · R02770 · 5.1.3.9-RXN · reversible

an N-acyl-D-glucosamine 6-phosphate
⇌
an N-acyl-alpha-D-mannosamine 6-phosphate
VK055_3851

ACETOOHBUTREDUCTOISOM-RXN

EC 1.1.1.86 · ACETOOHBUTREDUCTOISOM-RXN · not reversible

(S)-2-aceto-2-hydroxybutanoate H+ NADPH
→
(R)-2,3-dihydroxy-3-methylpentanoate NADP+
VK055_3202

ALDOSE1EPIM-RXN

EC 5.1.3.3 · ALDOSE1EPIM-RXN · not reversible

consuming
beta-D-galactopyranose
→
alpha-D-galactopyranose
VK055_1766

AMYLOMALT-RXN

EC 2.4.1.25 · AMYLOMALT-RXN · reversible

D-glucopyranose maltotetraose
⇌
maltose maltotriose
VK055_3685

BIOTINLIG-RXN

EC 6.3.4.15 · BIOTINLIG-RXN · not reversible

a [biotin carboxyl-carrier protein]-L-lysine biotin ATP
→
a [biotin carboxyl-carrier protein]-N6-biotinyl-L-lysine AMP H+ diphosphate
No mapped protein

BUTYRYL-COA-DEHYDROGENASE-RXN

EC 1.3.8.1 · R01178 · BUTYRYL-COA-DEHYDROGENASE-RXN · reversible

an oxidized electron-transfer flavoprotein butanoyl-CoA H+
⇌
a reduced electron-transfer flavoprotein crotonyl-CoA
No mapped protein

CITC-RXN

EC 6.2.1.22 · R04449 · CITC-RXN · not reversible

a holo [citrate lyase acyl-carrier protein] acetate ATP
→
an acetyl-holo [citrate lyase acyl-carrier protein] AMP diphosphate
VK055_2541

CITRATE-PRO-3S-LYASE-THIOLESTERASE-RXN

EC 3.1.2.16 · CITRATE-PRO-3S-LYASE-THIOLESTERASE-RXN · not reversible

an acetyl-holo [citrate lyase acyl-carrier protein] H2O
→
a holo [citrate lyase acyl-carrier protein] acetate H+
No mapped protein

CITRYLY-RXN

EC 4.1.3.34 · CITRYLY-RXN · not reversible

consuming
a citryl-holo [citrate lyase acyl-carrier protein]
→
an acetyl-holo [citrate lyase acyl-carrier protein] oxaloacetate H+
VK055_2539 VK055_2540

CITTRANS-RXN

EC 2.8.3.10 · CITTRANS-RXN · not reversible

producing
an acetyl-holo [citrate lyase acyl-carrier protein] citrate H+
→
a citryl-holo [citrate lyase acyl-carrier protein] acetate
VK055_2538 VK055_2539 VK055_2540

COBALAMIN5PSYN-RXN

EC 2.7.8.26 · R11174 · COBALAMIN5PSYN-RXN · not reversible

adenosylcobinamide-GDP alpha-ribazole 5'-phosphate
→
adenosylcobalamin 5'-phosphate GMP H+
VK055_5056

DARABALDOL-RXN

EC 4.1.2.17 · DARABALDOL-RXN · reversible

D-ribulose 1-phosphate
⇌
glycerone phosphate glycolaldehyde
VK055_4360

DARABKIN-RXN

EC 2.7.1.51 · DARABKIN-RXN · not reversible

D-ribulose ATP
→
D-ribulose 1-phosphate ADP H+
VK055_4357

DHHB-METHYLTRANSFER-RXN

EC 2.1.1.64 · DHHB-METHYLTRANSFER-RXN · not reversible

3-demethylubiquinol-8 S-adenosyl-L-methionine
→
S-adenosyl-L-homocysteine ubiquinol-8 H+
VK055_4874

DIHYDLIPACETRANS-RXN

EC 2.3.1.12 · DIHYDLIPACETRANS-RXN · not reversible

acetyl-CoA dihydrolipoamide
→
S-acetyldihydrolipoamide coenzyme A
VK055_2451

FERRIC-CHELATE-REDUCTASE-RXN

EC - · R00092 · FERRIC-CHELATE-REDUCTASE-RXN · not reversible

a siderophore-bound Fe(III) NADH
→
a siderophore-bound Fe(II) H+ NAD+
No mapped protein

FUC4NACTRANS-RXN

EC 2.4.1.325 · FUC4NACTRANS-RXN · not reversible

consuming
beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-PP-Und dTDP-4-acetamido-alpha-D-fucose
→
alpha-D-Fuc4NAc-(1->4)-beta-D-ManNAcA-(1->4)-GlcNAc-PP-Und dTDP H+
VK055_3182

GDPPYPHOSKIN-RXN

EC 2.7.6.5 · GDPPYPHOSKIN-RXN · not reversible

ATP GDP
→
ppGpp AMP H+
No mapped protein

GLCNACPTRANS-RXN

EC 2.7.8.33 · R08856 · GLCNACPTRANS-RXN · not reversible

producing
UDP-N-acetyl-alpha-D-glucosamine di-trans,octa-cis-undecaprenyl phosphate
→
alpha-D-GlcNAc-PP-Und UMP
VK055_3191

HYDROG-RXN

EC 1.12.7.2 · R00019 · HYDROG-RXN · reversible

H2 an oxidized ferredoxin [iron-sulfur] cluster
⇌
a reduced ferredoxin [iron-sulfur] cluster H+
VK055_4458

LEUCYLTRANSFERASE-RXN

EC 2.3.2.6 · R03813 · LEUCYLTRANSFERASE-RXN · not reversible

an L-leucyl-[tRNALeu] an N-terminal L-lysyl-[protein]
→
a [protein] N-terminal L-leucyl-L-lysine a tRNALeu H+
VK055_1569

MALTACETYLTRAN-RXN

EC 2.3.1.79 · R01556 · MALTACETYLTRAN-RXN · not reversible

acetyl-CoA maltose
→
6-O-acetyl-alpha-D-glucopyranosyl-(1->4)-D-glucose coenzyme A
VK055_2110

MERCAPYSTRANS-RXN

EC 2.8.1.2 · R03106 · MERCAPYSTRANS-RXN · not reversible

2-oxo-3-sulfanylpropanoate a reduced thioredoxin
→
an oxidized thioredoxin hydrogen sulfide pyruvate
VK055_4649

PRODISULFREDUCT-A-RXN

EC - · PRODISULFREDUCT-A-RXN · not reversible

an oxidized glutaredoxin glutathione
→
a reduced glutaredoxin glutathione disulfide
No mapped protein

PSERPHOSPHA-RXN

EC 3.1.3.3 · PSERPHOSPHA-RXN · not reversible

L(or D)-O-phosphoserine H+ H2O
→
D-or-L-serine phosphate
VK055_2588

PYROGLUTAMYL-PEPTIDASE-I-RXN

EC 3.4.19.3 · PYROGLUTAMYL-PEPTIDASE-I-RXN · not reversible

consuming
a [protein] with an N-terminal 5-oxo-L-proline H2O
→
5-oxo-L-proline a peptide
VK055_1804

RXN0-1132

EC 1.8.1.4 · RXN0-1132 · not reversible

a [pyruvate dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine NAD+
→
a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine H+ NADH
VK055_2296 VK055_2450

RXN0-1134

EC 1.2.4.1 · R01699 · RXN0-1134 · not reversible

a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine pyruvate H+
→
a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine CO2
VK055_2452

RXN0-1141

EC 6.3.1.20 · RXN0-1141 · not reversible

(R)-lipoate [glycine cleavage system lipoyl-carrier protein]-L-lysine ATP
→
a [glycine-cleavage complex H protein] N6-[(R)-lipoyl]-L-lysine AMP H+ diphosphate
VK055_2590 VK055_5062

RXN0-1321

EC 2.4.2.29 · R10209 · RXN0-1321 · not reversible

both
a guanine34 in tRNA preQ1
→
a 7-aminomethyl-7-deazaguanosine34 in tRNA guanine
VK055_2197

RXN0-1342

EC 2.4.99.17 · RXN0-1342 · not reversible

both
S-adenosyl-L-methionine a 7-aminomethyl-7-deazaguanosine34 in tRNA
→
L-methionine adenine an epoxyqueuosine34 in tRNA H+
VK055_2198

RXN0-1661

EC 3.1.1.- · RXN0-1661 · not reversible

enterobactin H2O
→
N-(2,3-dihydroxybenzoyl)-L-serine H+
VK055_1933

RXN0-2001[CCO-CYTOSOL]-CPD0-1189/KDO2-LIPID-A//L-ARA4N-MODIFIED-KDO2-LIPID-A/CPD-9646.76.

EC 2.4.2.43 · RXN0-2001[CCO-CYTOSOL]-CPD0-1189/KDO2-LIPID-A//L-ARA4N-MODIFIED-KDO2-LIPID-A/CPD-9646.76. · not reversible

4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate alpha-D-Kdo-(2->4)-alpha-D-Kdo-(2->6)-lipid A (E. coli)
→
alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-[P4'-alpha-L-ara4N]-lipid A (E. coli) di-trans,octa-cis-undecaprenyl phosphate
No mapped protein

RXN0-2001[CCO-PERI-BAC]-CPD0-1189/KDO2-LIPID-A//L-ARA4N-MODIFIED-KDO2-LIPID-A/CPD-9646.77.

EC 2.4.2.43 · RXN0-2001[CCO-PERI-BAC]-CPD0-1189/KDO2-LIPID-A//L-ARA4N-MODIFIED-KDO2-LIPID-A/CPD-9646.77. · not reversible

4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate alpha-D-Kdo-(2->4)-alpha-D-Kdo-(2->6)-lipid A (E. coli)
→
alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-[P4'-alpha-L-ara4N]-lipid A (E. coli) di-trans,octa-cis-undecaprenyl phosphate
No mapped protein

RXN0-2023

EC 2.8.1.13 · RXN0-2023 · not reversible

a [tRNA-uridine 2-sulfurtransferase]-S-sulfanyl-L-cysteine a reduced two electron carrier a uridine34 in tRNA ATP
→
a 2-thiouridine34 in tRNA a [tRNA-uridine 2-sulfurtransferase]-L-cysteine an oxidized electron carrier AMP H+ diphosphate
No mapped protein

RXN0-2281

EC 2.9.1.3 · RXN0-2281 · not reversible

a 5-[(methylamino)methyl]-2-thiouridine34 in tRNA geranyl diphosphate selenophosphate H2O
→
(2E)-3,7-dimethylocta-2,6-diene-1-thiol a 5-methylaminomethyl-2-selenouridine34 in tRNA diphosphate phosphate
VK055_2071

RXN0-2361

EC 6.3.2.45 · R10901 · RXN0-2361 · not reversible

L-alanyl-gamma-D-glutamyl-meso-diaminopimelate UDP-N-acetyl-alpha-D-muramate ATP
→
UDP-MurNAc-L-Ala-gamma-D-Glu-meso-DAP ADP H+ phosphate
No mapped protein

RXN0-2441

EC 2.1.1.144 · R05763 · RXN0-2441 · not reversible

S-adenosyl-L-methionine trans-aconitate
→
(E)-3-(methoxycarbonyl)pent-2-enedioate S-adenosyl-L-homocysteine
VK055_0843

RXN0-268

EC 2.8.3.27 · RXN0-268 · reversible

propanoyl-CoA succinate
⇌
propanoate succinyl-CoA
No mapped protein

RXN0-313

EC 4.1.2.- · RXN0-313 · reversible

beta-D-fructofuranose 6-phosphate
⇌
D-glyceraldehyde 3-phosphate dihydroxyacetone
VK055_3234

RXN0-4121

EC 3.9.1.- · RXN0-4121 · reversible

GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester) 5'-phosphoramidate H2O
⇌
N-alpha-acetyl lysine methyl ester GMP
VK055_1365

RXN0-4621

EC 2.7.1.170 · R09640 · RXN0-4621 · not reversible

consuming
1,6-anhydro-N-acetyl-beta-D-muramate ATP H2O
→
N-acetyl-D-muramate 6-phosphate ADP H+
VK055_0499

RXN0-5055

EC 2.1.3.15 · RXN0-5055 · not reversible

consuming
a [carboxyl-carrier protein dimer]-N6-carboxybiotinyl-L-lysine acetyl-CoA
→
a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine malonyl-CoA
VK055_2367 VK055_3811 VK055_3812 VK055_4807

RXN0-5063

EC 2.8.4.3 · RXN0-5063 · not reversible

consuming
N6-(3-methylbut-2-en-1-yl)-adenine37 in tRNA S-adenosyl-L-methionine a [3Fe-4S] iron-sulfur cluster a reduced two electron carrier
→
2-(methylsulfanyl)-N6-prenyladenosine37 in tRNA 5'-deoxyadenosine L-methionine S-adenosyl-L-homocysteine a [3Fe-3S] iron-sulfur cluster an oxidized electron carrier H+
VK055_1799 VK055_1845

RXN0-5098

EC 6.3.1.20 · RXN0-5098 · not reversible

a [lipoyl-carrier protein]-L-lysine octanoate ATP
→
a [lipoyl-carrier protein] N6-octanoyl-L-lysine AMP H+ diphosphate
VK055_2590 VK055_5062

RXN0-5122

EC 2.4.99.25 · RXN0-5122 · not reversible

ADP-L-glycero-beta-D-manno-heptose glucosyl-(heptosyl)2-Kdo2-lipid A-phosphate
→
glucosyl-(heptosyl)3-Kdo2-lipid A-phosphate (E. coli) ADP H+
VK055_3501

RXN0-5141

EC 1.1.1.91 · RXN0-5141 · not reversible

4-nitrobenzaldehyde H+ NADPH
→
4-nitrobenzyl alcohol NADP+
VK055_2345

RXN0-5144

EC 2.1.1.61 · R00601 · RXN0-5144 · not reversible

both
S-adenosyl-L-methionine a 5-(aminomethyl)-2-thiouridine34 in tRNA
→
S-adenosyl-L-homocysteine a 5-[(methylamino)methyl]-2-thiouridine34 in tRNA H+
VK055_1321

RXN0-5223

EC 2.7.1.- · RXN0-5223 · not reversible

a phosphatidylglycerol ATP
→
a phosphatidylglycerophosphate ADP H+
VK055_4993

RXN0-5225

EC 3.5.1.28 · RXN0-5225 · not reversible

producing
GlcNAc-1,6-anhMurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala H2O
→
L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine N-acetyl-beta-D-glucosamine-1,6-anhydro-N-acetyl-beta-D-muramate
VK055_1266 VK055_2459 VK055_4300 VK055_4733

RXN0-5226

EC 3.2.1.52 · RXN0-5226 · not reversible

N-acetyl-beta-D-glucosamine-1,6-anhydro-N-acetyl-beta-D-muramate H2O
→
1,6-anhydro-N-acetyl-beta-D-muramate N-acetyl-D-glucosamine
VK055_1361

RXN0-5229

EC 1.1.1.414 · RXN0-5229 · not reversible

L-galactonate NAD+
→
D-tagaturonate H+ NADH
VK055_2634

RXN0-5231

EC 2.3.1.- · RXN0-5231 · not reversible

acetyl-CoA an N-terminal-L-seryl-[ribosomal protein L12]
→
an N-terminal Nalpha-acetyl-L-seryl-[ribosomal protein L7] H+ coenzyme A
VK055_0536

RXN0-5305

EC - · RXN0-5305 · reversible

beta-D-ribofuranose
⇌
aldehydo-D-ribose
No mapped protein

RXN0-5306

EC 5.1.3.32 · R10819 · RXN0-5306 · not reversible

producing
alpha-L-rhamnopyranose
→
beta-L-rhamnopyranose
VK055_3272

RXN0-5364

EC 1.1.3.- · RXN0-5364 · not reversible

(S)-2-hydroxyglutarate dioxygen
→
2-oxoglutarate hydrogen peroxide
VK055_2309

RXN0-5390

EC 3.1.2.- · RXN0-5390 · not reversible

(3E,5Z)-tetradeca-3,5-dienoyl-CoA H2O
→
(3E,5Z)-tetradeca-3,5-dienoate H+ coenzyme A
VK055_1214 VK055_2137

RXN0-5391

EC 5.3.3.8 · RXN0-5391 · reversible

(2E,5Z)-tetradec-2,5-enoyl-CoA
⇌
(3E,5Z)-tetradeca-3,5-dienoyl-CoA
No mapped protein

RXN0-5414

EC 3.5.1.- · RXN0-5414 · not reversible

poly-beta-1,6-N-acetyl-D-glucosamine H2O
→
a partially deacetylated poly-beta-1,6-N-acetyl-D-glucosamine acetate
VK055_2949

RXN0-5418

EC 2.3.1.193 · RXN0-5418 · not reversible

a cytidine34 in [elongator tRNAmet] acetyl-CoA ATP H2O
→
an N4-acetylcytidine34 in [elongator tRNAmet] ADP H+ coenzyme A phosphate
VK055_4703

RXN0-5461

EC 2.7.1.189 · R11183 · RXN0-5461 · not reversible

producing
(4S)-4,5-dihydroxypentane-2,3-dione ATP
→
(2S)-2-hydroxy-3,4-dioxopentyl phosphate ADP H+
VK055_3959

RXN0-5515

EC 2.7.7.41 · RXN0-5515 · not reversible

a 2,3,4-saturated 1,2-diacyl-sn-glycerol 3-phosphate CTP H+
→
a CDP-2,3,4-saturated-diacylglycerol diphosphate
VK055_0972

RXN0-6259

EC 1.3.5.3 · RXN0-6259 · not reversible

a menaquinone protoporphyrinogen IX
→
a menaquinol protoporphyrin IX
No mapped protein

RXN0-6368

EC - · RXN0-6368 · not reversible

7,8-dihydromonapterin triphosphate H2O
→
7,8-dihydromonapterin H+ phosphate
No mapped protein

RXN0-6427

EC 3.1.7.2 · RXN0-6427 · not reversible

pppGpp H2O
→
GTP diphosphate
VK055_3470

RXN0-6720

EC - · RXN0-6720 · reversible

3-hydroxy-2,4-dioxopentyl phosphate H2O
⇌
3,4,4-trihydroxy-5-phosphooxypentan-2-one
VK055_3966

RXN0-6721

EC - · RXN0-6721 · not reversible

L-methionine hydrogen peroxide
→
L-methionine S-oxide H2O
No mapped protein

RXN0-6734

EC 4.7.1.1 · RXN0-6734 · not reversible

consuming
S-adenosyl-L-methionine a reduced two electron carrier alpha-D-ribose-1-methylphosphonate 5-phosphate
→
5'-deoxyadenosine 5-phospho-alpha-D-ribose 1,2-cyclic phosphate L-methionine an oxidized electron carrier methane H+
VK055_2970

RXN0-6948

EC 2.3.1.1 · RXN0-6948 · not reversible

L-methionine acetyl-CoA
→
N-acetyl-L-methionine H+ coenzyme A
VK055_4299

RXN0-6973

EC 1.14.14.5 · RXN0-6973 · not reversible

producing
1-butanesulfonate FMNH2 dioxygen
→
1-butanal FMN sulfite H+ H2O
VK055_1516 VK055_4365

RXN0-6998

EC 2.1.1.266 · RXN0-6998 · not reversible

S-adenosyl-L-methionine adenine2030 in 23S rRNA
→
S-adenosyl-L-homocysteine an N6-methyladenine2030 in 23S rRNA H+
VK055_3888

RXN0-6999

EC 6.3.2.- · RXN0-6999 · not reversible

(R)-beta-lysine a [protein chain elongation factor P]-L-lysine34 ATP
→
[a protein chain elongation factor EF-P]-N-(beta-L-lysyl)-L-lysine34 AMP H+ diphosphate
VK055_2911

RXN0-7012

EC 2.7.8.41 · RXN0-7012 · not reversible

a phosphatidylethanolamine a phosphatidylglycerol
→
a cardiolipin ethanolamine
VK055_0265 VK055_1714

RXN0-7014

EC 2.3.1.280 · RXN0-7014 · not reversible

(aminomethyl)phosphonate acetyl-CoA
→
(acetamidomethyl)phosphonate coenzyme A
No mapped protein

RXN0-7066

EC - · RXN0-7066 · not reversible

S-adenosyl-L-methionine prephenate
→
3-phenyl-2-oxopropanoate S-adenosyl-S-carboxymethyl-L-homocysteine H2O
No mapped protein

RXN0-7067

EC - · RXN0-7067 · not reversible

S-adenosyl-S-carboxymethyl-L-homocysteine a 5-hydroxyuridine34 in tRNA
→
S-adenosyl-L-homocysteine a 5-(carboxymethoxy)uridine34 in tRNA H+
No mapped protein

RXN0-7080

EC - · RXN0-7080 · not reversible

hydroxyl radical CTP
→
5-hydroxy-CTP H2O
No mapped protein

RXN0-7081

EC - · RXN0-7081 · not reversible

a 5-carboxymethylaminomethyl-2-thiouridine34 in tRNA an oxidized electron carrier H2O
→
a 5-(aminomethyl)-2-thiouridine34 in tRNA a reduced two electron carrier glyoxylate
No mapped protein

RXN0-7167

EC 2.1.1.- · RXN0-7167 · not reversible

both
S-adenosyl-L-methionine a 5-(carboxymethoxy)uridine34 in tRNA
→
S-adenosyl-L-homocysteine a 5-(methoxycarbonylmethoxy)uridine34 in tRNA
VK055_0063

RXN0-7168

EC 2.1.1.- · RXN0-7168 · not reversible

S-adenosyl-L-methionine a 5-(methoxycarbonylmethoxy)uridine34 in tRNA
→
S-adenosyl-L-homocysteine a 5-(methoxycarbonylmethoxy)-2'-O-methyluridine34 in tRNA H+
No mapped protein

RXN0-7169

EC - · RXN0-7169 · not reversible

an [HPr protein]-Npi-phospho-L-histidine dihydroxyacetone
→
an [HPr]-L-histidine glycerone phosphate
No mapped protein

RXN0-7187

EC - · RXN0-7187 · not reversible

L-methionine hydrogen peroxide
→
L-methionine-(S)-S-oxide H2O
No mapped protein

RXN0-7188

EC - · RXN0-7188 · not reversible

L-methionine hydrogen peroxide
→
L-methionine-(R)-S-oxide H2O
No mapped protein

RXN0-723

EC 1.1.98.6 · RXN0-723 · not reversible

formate CTP H+
→
dCTP CO2 H2O
VK055_2818

RXN0-724

EC 1.1.98.6 · RXN0-724 · not reversible

formate H+ UTP
→
dUTP CO2 H2O
VK055_2818

RXN0-7317

EC 2.6.1.82 · RXN0-7317 · reversible

2-oxoglutarate cadaverine
⇌
5-aminopentanal L-glutamate
VK055_3967

RXN0-7318

EC 1.2.1.19 · RXN0-7318 · not reversible

5-aminopentanal H2O NAD+
→
5-aminopentanoate H+ NADH
VK055_0557

RXN0-7349

EC - · RXN0-7349 · not reversible

a uridine34 in tRNA dioxygen
→
a 5-hydroxyuridine34 in tRNA
No mapped protein

RXN0-7389

EC - · RXN0-7389 · reversible

aceneuramate
⇌
N-acetyl-beta-neuraminate
No mapped protein

RXN0-7390

EC 4.1.3.3 · RXN0-7390 · reversible

aceneuramate
⇌
N-acetyl-D-mannosamine pyruvate
No mapped protein

RXN0-7437

EC 2.8.1.- · RXN0-7437 · not reversible

a [SufE sulfur-carrier protein]-L-cysteine a [SufS L-cysteine desulfurase]-S-sulfanyl-L-cysteine
→
a [SufE sulfur-carrier protein]-S-sulfanyl-L-cysteine a [SufS]-L-cysteine
VK055_0323 VK055_4349 VK055_4350 VK055_4639

RXN0-7440

EC - · RXN0-7440 · not reversible

both
L-selenocysteine a [selenocysteine lyase]-L-cysteine
→
L-alanine a [selenocysteine lyase]-S-selenopersulfide
VK055_0323

RXN0-7441

EC - · RXN0-7441 · not reversible

a [selenium-carrier protein]-L-cysteine a [selenocysteine lyase]-S-selenopersulfide
→
a [selenium-carrier protein]-S-selenopersulfide a [selenocysteine lyase]-L-cysteine
VK055_0323

RXN0-7442

EC 4.4.1.16 · RXN0-7442 · not reversible

L-selenocysteine a [selenium-carrier protein]-L-cysteine
→
L-alanine a [selenium-carrier protein]-S-selenopersulfide
VK055_0323

RXN0-745

EC 1.1.98.6 · RXN0-745 · not reversible

formate ATP H+
→
dATP CO2 H2O
VK055_2818

RXN0-746

EC 1.1.98.6 · RXN0-746 · not reversible

formate GTP H+
→
dGTP CO2 H2O
VK055_2818

RXN0-7485

EC 4.2.1.32 · RXN0-7485 · reversible

meso-tartrate
⇌
oxaloacetate H2O
VK055_3838

RXN0-7489[CCO-CYTOSOL]-A-DONOR-PG-WITH-MESODAP-TETRAPEPTIDE/AN-ACCEPTOR-PG-WITH-MESODAP-TETRAPEPTIDE//CPD-17947/D-ALANINE.112.

EC - · RXN0-7489[CCO-CYTOSOL]-A-DONOR-PG-WITH-MESODAP-TETRAPEPTIDE/AN-ACCEPTOR-PG-WITH-MESODAP-TETRAPEPTIDE//CPD-17947/D-ALANINE.112. · not reversible

a donor peptidoglycan with (L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide an acceptor peptidoglycan with (L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide
→
D-alanine a peptidoglycan with L,D cross links (meso-diaminopimelate containing)
VK055_0325 VK055_1353 VK055_1531 VK055_1678 VK055_2329 VK055_5141

RXN0-7489[CCO-PERI-BAC]-A-DONOR-PG-WITH-MESODAP-TETRAPEPTIDE/AN-ACCEPTOR-PG-WITH-MESODAP-TETRAPEPTIDE//CPD-17947/D-ALANINE.113.

EC - · RXN0-7489[CCO-PERI-BAC]-A-DONOR-PG-WITH-MESODAP-TETRAPEPTIDE/AN-ACCEPTOR-PG-WITH-MESODAP-TETRAPEPTIDE//CPD-17947/D-ALANINE.113. · not reversible

a donor peptidoglycan with (L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide an acceptor peptidoglycan with (L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide
→
D-alanine a peptidoglycan with L,D cross links (meso-diaminopimelate containing)
VK055_0325 VK055_1353 VK055_1531 VK055_1678 VK055_2329 VK055_5141

RXN0-947

EC 2.3.1.181 · R07766 · RXN0-947 · not reversible

a [lipoyl-carrier protein]-L-lysine an octanoyl-[acp]
→
a [lipoyl-carrier protein] N6-octanoyl-L-lysine a soluble [acyl-carrier protein] H+
VK055_1870

RXN-10

EC 6.3.4.5 · RXN-10 · not reversible

L-aspartate O-ureido-L-homoserine ATP
→
canavaninosuccinate AMP H+ diphosphate
VK055_3898

RXN-10015

EC - · RXN-10015 · not reversible

(4S)-4,5-dihydroxypentane-2,3-dione
→
(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one
No mapped protein

RXN-10016

EC - · RXN-10016 · not reversible

(4S)-4,5-dihydroxypentane-2,3-dione
→
(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one
No mapped protein

RXN-10017

EC - · RXN-10017 · not reversible

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one H2O
→
autoinducer 2
No mapped protein

RXN-10018

EC - · RXN-10018 · not reversible

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one H2O
→
(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran
No mapped protein

RXN-10085

EC 2.8.3.6 · RXN-10085 · reversible

4-methyl-3-oxoadipate succinyl-CoA
⇌
4-methyl-3-oxoadipyl-CoA succinate
VK055_0964 VK055_0965

RXN-10086

EC 2.3.1.174 · RXN-10086 · reversible

(2S)-methylsuccinyl-CoA acetyl-CoA
⇌
4-methyl-3-oxoadipyl-CoA coenzyme A
VK055_0963 VK055_1032

RXN-10381

EC 4.2.1.80 · RXN-10381 · not reversible

(3E)-5-chloro-2-oxopent-3-enoate H2O
→
5-chloro-4-hydroxy-2-oxopentanoate
VK055_0342

RXN-10442

EC 1.14.12.13 · RXN-10442 · not reversible

2-fluorobenzoate H+ NADH dioxygen
→
catechol fluoride CO2 NAD+
VK055_0611

RXN-10443

EC 1.14.12.13 · RXN-10443 · not reversible

2-bromobenzoate H+ NADH dioxygen
→
bromide catechol CO2 NAD+
VK055_0611

RXN-10444

EC 1.14.12.13 · RXN-10444 · not reversible

2-iodobenzoate H+ NADH dioxygen
→
catechol iodide CO2 NAD+
VK055_0611

RXN-10462

EC 2.3.1.15 · R09380 · RXN-10462 · not reversible

an acyl-[acyl-carrier protein] sn-glycerol 3-phosphate
→
a 2-lysophosphatidate a soluble [acyl-carrier protein]
VK055_3044

RXN-10674

EC 2.7.8.7 · RXN-10674 · reversible

an apo-AsbD acyl-carrier protein coenzyme A
⇌
a holo-[AsbD acyl-carrier protein] adenosine 3',5'-bisphosphate H+
VK055_2518 VK055_4613

RXN-10851

EC - · RXN-10851 · reversible

S-sulfanylglutathione a reduced two electron carrier
⇌
an oxidized electron carrier bisorganyltrisulfane hydrogen sulfide
No mapped protein

RXN-10857

EC 4.1.2.25 · RXN-10857 · not reversible

7,8-dihydromonapterin
→
6-(hydroxymethyl)-7,8-dihydropterin glycolaldehyde
VK055_4010

RXN-11028

EC 2.7.8.13 · RXN-11028 · not reversible

UDP-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Ala trans,octacis-decaprenyl phosphate
→
Dec-PP-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Ala UMP
VK055_2481

RXN-11029

EC 2.4.1.227 · RXN-11029 · reversible

Dec-PP-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Ala UDP-N-acetyl-alpha-D-glucosamine
⇌
Dec-PP-[beta-D-GlcNAc-(1->4)]-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Ala H+ UDP
VK055_2477

RXN-11115

EC - · RXN-11115 · not reversible

producing
L-cysteine ATP H+
→
(L-cysteinyl)adenylate diphosphate
VK055_2065

RXN-11176

EC 1.21.98.4 · RXN-11176 · not reversible

S-adenosyl-L-methionine a PqqA peptide with an E-X-X-X-Y motif
→
5'-deoxyadenosine L-methionine a PqqA peptide with linked Glu-Tyr residues H+
No mapped protein

RXN-11178

EC - · RXN-11178 · not reversible

2-amino-4-[5-(2-amino-2-carboxylatoethyl)-2-hydroxyphenyl]pentanedioate
→
2-amino-4-[3-(2-amino-2-carboxylatoethyl)-6-oxocyclohexa-1,4-dien-1-yl]pentanedioate
No mapped protein

RXN-11179

EC - · RXN-11179 · not reversible

2-amino-4-[3-(2-amino-2-carboxylatoethyl)-6-oxocyclohexa-1,4-dien-1-yl]pentanedioate
→
6-(2-amino-2-carboxylatoethyl)-1,2,3,4-tetrahydroquinoline-2,4-dicarboxylate H+ H2O
No mapped protein

RXN-11180

EC - · RXN-11180 · not reversible

6-(2-amino-2-carboxylatoethyl)-1,2,3,4-tetrahydroquinoline-2,4-dicarboxylate dioxygen
→
6-(2-amino-2-carboxylatoethyl)-7-hydroxy-8-oxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate
No mapped protein

RXN-11181

EC 1.3.3.11 · R07353 · RXN-11181 · not reversible

consuming
6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline 2,4-dicarboxylate dioxygen
→
pyrroloquinoline quinone H+ H2O hydrogen peroxide
VK055_0678

RXN-11346

EC 2.4.1.227 · RXN-11346 · reversible

UDP-N-acetyl-alpha-D-glucosamine Und-PP-MurNAc-L-Ala-gamma-D-Glu-L-Lys-D-Ala
⇌
Und-PP-beta-D-GlcNAc-(1->4)-MurNAc-L-Ala-gamma-D-Glu-L-Lys-D-Ala H+ UDP
VK055_2477

RXN-11347

EC 2.7.8.13 · RXN-11347 · reversible

UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanine di-trans,octa-cis-undecaprenyl phosphate
⇌
Und-PP-MurNAc-L-Ala-gamma-D-Glu-L-Lys-D-Ala UMP
VK055_2481

RXN-11361

EC 2.7.7.80 · RXN-11361 · not reversible

a molybdopterin synthase sulfur carrier subunit ATP H+
→
a carboxy-adenylated [molybdopterin-synthase sulfur-carrier protein subunit] diphosphate
No mapped protein

RXN-11397

EC 3.6.1.55 · RXN-11397 · not reversible

consuming
8-oxo-GTP H2O
→
8-oxo-GMP H+ diphosphate
VK055_2468

RXN-11409

EC - · RXN-11409 · not reversible

hydroxyl radical GTP
→
8-oxo-GTP H2O
No mapped protein

RXN-11410

EC - · RXN-11410 · not reversible

dGTP hydroxyl radical
→
8-oxo-dGTP H2O
No mapped protein

RXN-11459

EC 4.2.2.- · RXN-11459 · not reversible

consuming
alpha-D-galacturonosyl-(1->4)-alpha-D-galacturonate
→
4-deoxy-L-threo-hex-4-enopyranuronate D-galactopyranuronate
VK055_4256

RXN-11573

EC 2.1.1.187 · RXN-11573 · not reversible

S-adenosyl-L-methionine a guanine745 in 23S rRNA
→
S-adenosyl-L-homocysteine an N1-methylguanine745 in 23S rRNA H+
VK055_0112

RXN-11574

EC 2.1.1.173 · RXN-11574 · not reversible

S-adenosyl-L-methionine a guanine2445 in 23S rRNA
→
S-adenosyl-L-homocysteine an N2-methylguanine2445 in 23S rRNA H+
VK055_1510

RXN-11576

EC 2.1.1.172 · RXN-11576 · not reversible

S-adenosyl-L-methionine a guanine1207 in 16S rRNA
→
S-adenosyl-L-homocysteine an N2-methylguanine1207 in 16S rRNA H+
VK055_2604

RXN-11578

EC 2.1.1.170 · RXN-11578 · not reversible

S-adenosyl-L-methionine a guanine527 in 16S rRNA
→
S-adenosyl-L-homocysteine an N7-methylguanine527 in 16S rRNA
VK055_3328

RXN-11588

EC 2.1.1.185 · RXN-11588 · not reversible

S-adenosyl-L-methionine guanosine2251 in 23S rRNA
→
2-O-methylguanosine2251 in 23S rRNA S-adenosyl-L-homocysteine H+
VK055_2884

RXN-11589

EC 2.1.1.186 · RXN-11589 · not reversible

S-adenosyl-L-methionine a cytidine2498 in 23S rRNA
→
S-adenosyl-L-homocysteine a 2-O-methylcytidine2498 in 23S rRNA H+
VK055_4354

RXN-11591

EC 2.1.1.176 · RXN-11591 · not reversible

S-adenosyl-L-methionine a cytosine967 in 16S rRNA
→
S-adenosyl-L-homocysteine a 5-methylcytosine967 in 16S rRNA H+
VK055_3784

RXN-11592

EC 2.1.1.177 · RXN-11592 · not reversible

S-adenosyl-L-methionine a pseudouridine1915 in 23S rRNA
→
S-adenosyl-L-homocysteine an N3-methylpseudouridine1915 in 23S rRNA H+
VK055_1864

RXN-11593

EC 2.1.1.178 · RXN-11593 · not reversible

S-adenosyl-L-methionine a cytosine1407 in 16S rRNA
→
S-adenosyl-L-homocysteine a 5-methylcytosine1407 in 16S rRNA H+
VK055_0098

RXN-11596

EC 2.1.1.181 · R07232 · RXN-11596 · not reversible

S-adenosyl-L-methionine adenine1618 in 23S rRNA
→
S-adenosyl-L-homocysteine an N6-methyladenine1618 in 23S rRNA H+
VK055_1693

RXN-11598

EC 2.1.1.193 · RXN-11598 · not reversible

S-adenosyl-L-methionine a uracil1498 in 16S rRNA
→
S-adenosyl-L-homocysteine an N3-methyluracil1498 in 16S rRNA H+
VK055_4100

RXN-11600

EC 2.1.1.189 · RXN-11600 · not reversible

S-adenosyl-L-methionine a uracil747 in 23S rRNA
→
S-adenosyl-L-homocysteine a 5-methyluracil747 in 23S rRNA H+
VK055_1599

RXN-11601

EC 2.1.1.190 · RXN-11601 · not reversible

S-adenosyl-L-methionine a uracil1939 in 23S rRNA
→
S-adenosyl-L-homocysteine a 5-methyluracil1939 in 23S rRNA H+
VK055_4387

RXN-11635

EC 2.1.1.174 · R07234 · RXN-11635 · not reversible

S-adenosyl-L-methionine a guanine1835 in 23S rRNA
→
S-adenosyl-L-homocysteine an N2-methylguanine1835 in 23S rRNA H+
VK055_3957

RXN-11637

EC 2.1.1.198 · RXN-11637 · not reversible

S-adenosyl-L-methionine a cytidine1402 in 16S rRNA
→
S-adenosyl-L-homocysteine a 2'-O-methylcytidine1402 in 16S rRNA H+
VK055_3925

RXN-11791

EC 2.7.8.31 · RXN-11791 · not reversible

UDP-alpha-D-glucose di-trans,octa-cis-undecaprenyl phosphate
→
alpha-D-Glc-PP-Und UMP
VK055_5025

RXN-11811

EC - · RXN-11811 · reversible

H+ ammonia
⇌
ammonium
No mapped protein

RXN-11833

EC 5.4.99.19 · RXN-11833 · reversible

a uridine516 in 16S rRNA
⇌
a 16S rRNA pseudouridine516
VK055_4905

RXN-11834

EC 5.4.99.20 · RXN-11834 · not reversible

uridine2457 in 23S rRNA
→
a pseudouridine2457 in 23S rRNA
VK055_1319

RXN-11835

EC 5.4.99.21 · RXN-11835 · not reversible

a uridine2604 in 23S rRNA
→
a pseudouridine2604 in 23S rRNA
VK055_3064

RXN-11836

EC 5.4.99.22 · RXN-11836 · not reversible

uridine2605 in 23S rRNA
→
a pseudouridine2605 in 23S rRNA
VK055_1188

RXN-11842

EC 5.4.99.28 · RXN-11842 · not reversible

a uridine32 in tRNA
→
a pseudouridine32 in tRNA
VK055_2517

RXN-11845

EC 2.1.1.166 · RXN-11845 · not reversible

S-adenosyl-L-methionine uridine2552 in 23S rRNA
→
S-adenosyl-L-homocysteine a 2'-O-methyluridine2552 in 23S rRNA H+
VK055_3888

RXN-11860

EC 2.1.1.207 · RXN-11860 · not reversible

S-adenosyl-L-methionine a cytidine34 in tRNA
→
S-adenosyl-L-homocysteine a 2'-O-methylcytidine34 in tRNA H+
VK055_3520

RXN-11865

EC 2.1.1.207 · RXN-11865 · not reversible

S-adenosyl-L-methionine a 5-carboxymethylaminomethyluridine34 in tRNALeu
→
S-adenosyl-L-homocysteine a 5-carboxymethylaminomethyl-2'-O-methyluridine34 in tRNALeu H+
VK055_3520

RXN-11866

EC 2.1.1.200, 2.1.1.205 · RXN-11866 · not reversible

S-adenosyl-L-methionine a cytidine 32 in tRNA
→
S-adenosyl-L-homocysteine a 2'-O-methylcytidine32 in tRNA H+
VK055_4637

RXN-11867

EC 2.1.1.200 · RXN-11867 · not reversible

S-adenosyl-L-methionine a uridine32 in tRNA
→
S-adenosyl-L-homocysteine a 2'-O-methyluridine32 in tRNA H+
VK055_4637

RXN-12074

EC 4.1.3.17 · RXN-12074 · reversible

(R)-4-hydroxy-4-methyl-2-oxoglutarate
⇌
pyruvate
VK055_3417

RXN-12088

EC 3.2.1.22 · RXN-12088 · not reversible

an alpha-D-galactoside H2O
→
a non galactosylated galactose acceptor alpha-D-galactopyranose
VK055_3274

RXN-12104

EC 1.17.99.6 · RXN-12104 · not reversible

a reduced two electron carrier an epoxyqueuosine34 in tRNA
→
a queuosine in tRNA an oxidized electron carrier H2O
No mapped protein

RXN-12158

EC 1.1.1.378 · RXN-12158 · not reversible

L-rhamnofuranose NAD(P)+
→
L-rhamnono-1,4-lactone NAD(P)H H+
No mapped protein

RXN-12303

EC 1.6.5.2 · RXN-12303 · reversible

NAD(P)H a plastoquinone H+
⇌
NAD(P)+ a plastoquinol
VK055_1448

RXN-12458

EC 2.1.1.228 · R00597 · RXN-12458 · not reversible

S-adenosyl-L-methionine a guanine37 in tRNA
→
S-adenosyl-L-homocysteine an N1-methylguanine37 in tRNA H+
VK055_4570

RXN-12473

EC 2.8.1.11 · RXN-12473 · not reversible

both
a [molybdopterin synthase sulfurtransferase]-S-sulfanyl-L-cysteine a carboxy-adenylated [molybdopterin-synthase sulfur-carrier protein subunit] a reduced two electron carrier
→
a [molybdopterin synthase sulfurtransferase]-L-cysteine a thiocarboxylated [molybdopterin-synthase sulfur-carrier protein subunit] an oxidized electron carrier AMP H+
VK055_1668

RXN-12540

EC - · RXN-12540 · not reversible

Fe2+ hydrogen peroxide
→
Fe3+ OH- hydroxyl radical
No mapped protein

RXN-12541

EC - · RXN-12541 · not reversible

Fe2+ dioxygen
→
Fe3+ superoxide
No mapped protein

RXN-12611

EC 2.5.1.3 · R11312 · RXN-12611 · not reversible

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine H+
→
thiamine phosphate CO2 diphosphate
VK055_3099

RXN-12626

EC 3.2.1.52 · RXN-12626 · not reversible

producing
N,N',N''-triacetylchitotriose H2O
→
N,N'-diacetylchitobiose N-acetyl-D-glucosamine
VK055_1361

RXN-12721

EC 1.8.4.9 · RXN-12721 · not reversible

adenosine 5'-phosphoselenate glutathione
→
glutathione disulfide selenite AMP H+
No mapped protein

RXN-12753

EC - · RXN-12753 · not reversible

H2O NADH
→
(S)-NADHX
No mapped protein

RXN-12754

EC - · RXN-12754 · not reversible

H2O NADH
→
(R)-NADHX
No mapped protein

RXN-12865

EC 1.8.1.- · RXN-12865 · not reversible

selenodiglutathione H+ NADPH
→
glutathione glutathioselenol NADP+
No mapped protein

RXN-12867

EC 1.8.1.- · RXN-12867 · not reversible

glutathioselenol H+ NADPH
→
glutathione hydrogen selenide NADP+
No mapped protein

RXN-13031

EC 3.5.1.138 · RXN-13031 · not reversible

a [lipoyl-carrier protein]-N6-[(R)-lipoyl]-L-lysine H2O
→
(R)-lipoate a [lipoyl-carrier protein]-L-lysine
No mapped protein

RXN-13032

EC 2.3.1.200 · RXN-13032 · not reversible

a [glycine-cleavage complex H protein] N6-[(R)-lipoyl]-L-lysine a [lipoyl-carrier protein]-L-lysine
→
[glycine cleavage system lipoyl-carrier protein]-L-lysine a [lipoyl-carrier protein]-N6-[(R)-lipoyl]-L-lysine
No mapped protein

RXN-13039

EC - · RXN-13039 · not reversible

[(R)-lipoyl]adenylate [glycine cleavage system lipoyl-carrier protein]-L-lysine
→
a [glycine-cleavage complex H protein] N6-[(R)-lipoyl]-L-lysine AMP H+
VK055_2590 VK055_5062

RXN-13329

EC - · R10245 · RXN-13329 · not reversible

2-iminoacetate H+ H2O
→
glyoxylate ammonium
No mapped protein

RXN-13459

EC 5.3.2.6 · RXN-13459 · reversible

(2Z)-2-hydroxypenta-2,4-dienoate
⇌
(3E)-2-oxopent-3-enoate
No mapped protein

RXN-13460

EC - · RXN-13460 · not reversible

(S)-4-hydroxy-2-oxopentanoate
→
(2Z)-2,4-dihydroxypent-2-enoate
No mapped protein

RXN-13615

EC 1.3.8.7 · RXN-13615 · reversible

an oxidized electron-transfer flavoprotein decanoyl-CoA H+
⇌
(2E)-dec-2-enoyl-CoA a reduced electron-transfer flavoprotein
No mapped protein

RXN-13671

EC 1.2.1.10 · RXN-13671 · reversible

isobutanal NAD+ coenzyme A
⇌
isobutanoyl-CoA H+ NADH
VK055_0343

RXN-13747

EC 5.2.1.- · RXN-13747 · not reversible

(1Z,3Z)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate
→
(1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate
No mapped protein

RXN-13824

EC - · RXN-13824 · not reversible

producing
S-adenosyl-L-methionine precorrin-6B H+
→
S-adenosyl-L-homocysteine precorrin-7 CO2
VK055_4330 VK055_4331

RXN-13826

EC - · RXN-13826 · not reversible

consuming
S-adenosyl-L-methionine precorrin-7
→
S-adenosyl-L-homocysteine precorrin-8x H+
VK055_4330 VK055_4331

RXN-13870

EC 2.3.1.5 · RXN-13870 · not reversible

3-amino-4-hydroxybenzoate acetyl-CoA
→
3-acetylamino-4-hydroxybenzoate coenzyme A
VK055_0599

RXN-13871

EC 2.3.1.5 · RXN-13871 · not reversible

3-amino-4-hydroxybenzaldehyde acetyl-CoA
→
3-acetylamino-4-hydroxybenzaldehyde H+ coenzyme A
VK055_0599

RXN-14056

EC - · R11028 · RXN-14056 · reversible

(R)-methylmalonate-semialdehyde
⇌
(S)-methylmalonate-semialdehyde
No mapped protein

RXN-14129

EC 3.5.4.1 · RXN-14129 · reversible

5-fluorocytosine H+ H2O
⇌
5-fluorouracil ammonium
VK055_4618

RXN-14188

EC 3.6.1.- · RXN-14188 · not reversible

5-hydroxy-CTP H2O
→
5-hydroxy-CMP H+ diphosphate
No mapped protein

RXN-14206

EC 4.2.1.96 · RXN-14206 · not reversible

a 4a-hydroxytetrahydrobiopterin
→
6,7-dihydrobiopterin H2O
No mapped protein

RXN-14249

EC 1.1.1.103 · RXN-14249 · not reversible

L-threonine NAD+
→
aminoacetone CO2 NADH
VK055_3510

RXN-14260

EC 2.4.1.25 · RXN-14260 · reversible

D-glucopyranose maltopentaose
⇌
maltose maltotetraose
VK055_3685

RXN-14261

EC 2.4.1.25 · RXN-14261 · reversible

D-glucopyranose maltohexaose
⇌
maltopentaose maltose
VK055_3685

RXN-14290

EC - · RXN-14290 · not reversible

dATP hydroxyl radical
→
2-hydroxy-dATP H2O
No mapped protein

RXN-14291

EC 2.5.1.39 · RXN-14291 · reversible

4-aminobenzoate all-trans-hexaprenyl diphosphate
⇌
4-amino-3-(all trans-hexaprenyl)benzoate diphosphate
VK055_3045

RXN-14362

EC 5.1.2.7 · RXN-14362 · not reversible

D-tagaturonate
→
D-fructuronate
No mapped protein

RXN-14393

EC 1.1.1.211, 1.1.1.35 · RXN-14393 · reversible

(S)-3-hydroxy-(5Z)-tetradecenoyl-CoA NAD+
⇌
3-oxo-(5Z)-tetradecenoyl-CoA H+ NADH
No mapped protein

RXN-14408

EC - · RXN-14408 · reversible

aldehydo-D-glucose
⇌
D-glucopyranose
No mapped protein

RXN-14408-CPD-15374//GLC.15.

EC - · RXN-14408-CPD-15374//GLC.15. · reversible

aldehydo-D-glucose
⇌
beta-D-glucopyranose
No mapped protein

RXN-14409

EC - · RXN-14409 · reversible

aldehydo-D-galactose
⇌
D-galactopyranose
No mapped protein

RXN-14477

EC 3.1.1.107 · RXN-14477 · not reversible

producing
enterobactin H2O
→
N-(2,3-dihydroxybenzoyl)-L-serine trimer H+
VK055_1933

RXN-14478

EC 3.1.1.- · RXN-14478 · not reversible

both
N-(2,3-dihydroxybenzoyl)-L-serine trimer H2O
→
N-(2,3-dihydroxybenzoyl)-L-serine N-(2,3-dihydroxybenzoyl)-L-serine dimer H+
VK055_1933

RXN-14479

EC 3.1.1.- · RXN-14479 · not reversible

consuming
N-(2,3-dihydroxybenzoyl)-L-serine dimer H2O
→
N-(2,3-dihydroxybenzoyl)-L-serine H+
VK055_1933

RXN-14517

EC 2.1.1.228 · RXN-14517 · not reversible

S-adenosyl-L-methionine guanine37 in tRNAPhe
→
S-adenosyl-L-homocysteine an N1-methylguanine37 in tRNAPhe H+
VK055_4570

RXN-14693

EC - · RXN-14693 · reversible

D-glucopyranuronate
⇌
aldehydo-D-glucuronate
No mapped protein

RXN-14724

EC 2.8.3.13 · RXN-14724 · not reversible

glutarate succinyl-CoA
→
glutaryl-CoA succinate
No mapped protein

RXN-14753

EC - · RXN-14753 · reversible

D-galactopyranuronate
⇌
aldehydo-D-galacturonate
No mapped protein

RXN-14806

EC - · RXN-14806 · reversible

D-arabinopyranose
⇌
aldehydo-D-arabinose
No mapped protein

RXN-14807

EC - · RXN-14807 · reversible

D-arabinofuranose
⇌
D-arabinopyranose
No mapped protein

RXN-14808

EC - · RXN-14808 · reversible

aldehydo-L-arabinose
⇌
L-arabinopyranose
No mapped protein

RXN-14809

EC - · RXN-14809 · reversible

L-arabinofuranose
⇌
L-arabinopyranose
No mapped protein

RXN-14812

EC - · RXN-14812 · reversible

keto-D-fructose 6-phosphate
⇌
beta-D-fructofuranose 6-phosphate
No mapped protein

RXN-14812-FRUCTOSE-6P//FRUCTOSE-6P.25.

EC - · RXN-14812-FRUCTOSE-6P//FRUCTOSE-6P.25. · reversible

beta-D-fructofuranose 6-phosphate
⇌
beta-D-fructofuranose 6-phosphate
No mapped protein

RXN-14814

EC 2.7.7.- · RXN-14814 · not reversible

producing
L-aspartate ATP H+
→
(L-aspartyl)adenylate diphosphate
VK055_0067

RXN-14815

EC 5.1.3.- · RXN-14815 · reversible

alpha-D-mannopyranose 6-phosphate
⇌
beta-D-mannopyranose 6-phosphate
No mapped protein

RXN-14850

EC - · RXN-14850 · reversible

D-altropyranose
⇌
aldehydo-D-altrose
No mapped protein

RXN-14882

EC - · RXN-14882 · reversible

aldehydo-D-ribose
⇌
D-ribofuranose
No mapped protein

RXN-14883

EC - · RXN-14883 · reversible

aldehydo-D-ribose
⇌
D-ribopyranose
No mapped protein

RXN-14904

EC - · RXN-14904 · reversible

alpha-D-ribofuranose
⇌
beta-D-ribofuranose
No mapped protein

RXN-14960

EC - · RXN-14960 · not reversible

a siderophore-bound Fe(II) H+
→
Fe2+ a siderophore
No mapped protein

RXN-14969

EC 5.3.1.3 · RXN-14969 · reversible

D-altropyranose
⇌
keto-D-psicose
VK055_4358

RXN-14997

EC - · RXN-14997 · not reversible

alpha-D-ribose 5-phosphate
→
aldehydo-D-ribose 5-phosphate
No mapped protein

RXN-15121

EC - · R11101 · RXN-15121 · not reversible

(Z)-2-aminobutenoate
→
2-iminobutanoate
No mapped protein

RXN-15122

EC - · RXN-15122 · not reversible

producing
L-threonine
→
(Z)-2-aminobutenoate H2O
VK055_3203

RXN-15123

EC 3.5.99.10 · R11098 · RXN-15123 · not reversible

2-iminobutanoate H2O
→
2-oxobutanoate ammonium
No mapped protein

RXN-15124

EC - · R11100 · RXN-15124 · not reversible

2-aminoprop-2-enoate
→
2-iminopropanoate
No mapped protein

RXN-15127

EC 3.5.99.10 · R11099 · RXN-15127 · not reversible

2-iminopropanoate H2O
→
pyruvate ammonium
No mapped protein

RXN-15139

EC - · RXN-15139 · not reversible

adenine hydroxyl radical
→
isoguanine H2O
No mapped protein

RXN-15140

EC - · RXN-15140 · not reversible

2'-deoxyadenosine hydroxyl radical
→
2-oxo-2'-deoxyadenosine H2O
No mapped protein

RXN-15216

EC 5.3.1.32 · R10939 · RXN-15216 · not reversible

(2S)-2-hydroxy-3,4-dioxopentyl phosphate
→
3-hydroxy-2,4-dioxopentyl phosphate
No mapped protein

RXN-15261

EC 3.5.4.3 · RXN-15261 · reversible

7,8-dihydropterin H+ H2O
⇌
7,8-dihydrolumazine ammonium
VK055_0697

RXN-15308

EC 1.14.13.- · RXN-15308 · not reversible

2-(all-trans-nonaprenyl)phenol H+ NADPH dioxygen
→
2-(all-trans-nonaprenyl)benzene-1,4-diol H2O NADP+
VK055_3145

RXN-15341

EC 1.14.14.5 · RXN-15341 · not reversible

3-(N-morpholino)propanesulfonate FMNH2 dioxygen
→
3-(N-morpholino)propanal FMN sulfite H+ H2O
VK055_1516 VK055_4365

RXN-15345

EC - · RXN-15345 · not reversible

alpha-D-ribose 5-phosphate
→
beta-D-ribose 5-phosphate
No mapped protein

RXN-15346

EC - · RXN-15346 · not reversible

beta-D-ribose 5-phosphate
→
aldehydo-D-ribose 5-phosphate
No mapped protein

RXN-15348

EC - · RXN-15348 · reversible

S-sulfanylglutathione glutathione
⇌
glutathione disulfide hydrogen sulfide
No mapped protein

RXN-15356

EC - · RXN-15356 · not reversible

keto-L-rhamnulose
→
L-rhamnulofuranose
No mapped protein

RXN-15446

EC 1.1.99.- · RXN-15446 · not reversible

6-(2-amino-2-carboxylatoethyl)-7-hydroxy-8-oxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate an oxidized electron carrier
→
6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline 2,4-dicarboxylate a reduced two electron carrier
No mapped protein

RXN-15510

EC - · RXN-15510 · reversible

2-phospho-D-glycerate a [protein]-Npi-phospho-L-histidine
⇌
2,3-diphospho-D-glycerate a [protein]-L-histidine
VK055_2580

RXN-15511

EC - · RXN-15511 · reversible

2,3-diphospho-D-glycerate a [protein]-L-histidine
⇌
3-phospho-D-glycerate a [protein]-Npi-phospho-L-histidine
VK055_2580

RXN-15513

EC 5.4.2.11 · RXN-15513 · reversible

2-phospho-D-glycerate
⇌
3-phospho-D-glycerate
VK055_2580

RXN-15635

EC 2.1.2.11 · RXN-15635 · reversible

3-methyl-2-oxobutanoate 5,10-methylene-tetrahydromethanopterin H2O
⇌
2-dehydropantoate tetrahydromethanopterin
VK055_2427

RXN-15650

EC 2.6.1.117 · RXN-15650 · reversible

4-(methylsulfanyl)-2-oxobutanoate L-glutamine
⇌
2-oxoglutaramate L-methionine
No mapped protein

RXN-15651

EC - · RXN-15651 · not reversible

2-oxoglutaramate
→
2-hydroxy-5-oxoproline
No mapped protein

RXN-15727

EC 2.8.3.8 · RXN-15727 · not reversible

acetate pentanoyl-CoA
→
acetyl-CoA pentanoate
VK055_4879

RXN-15733

EC 2.7.6.3 · RXN-15733 · not reversible

6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin ATP
→
[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate AMP H+
VK055_2426

RXN-15742

EC 4.3.2.- · RXN-15742 · reversible

4-(beta-D-ribofuranosyl)-N-succinylaminobenzene 5'-phosphate
⇌
4-(beta-D-ribofuranosyl)aminobenzene-5'-phosphate fumarate
VK055_1323

RXN-15943

EC 2.3.1.245 · R11182 · RXN-15943 · not reversible

3-hydroxy-2,4-dioxopentyl phosphate coenzyme A
→
acetyl-CoA glycerone phosphate
No mapped protein

RXN-16002

EC - · R06830 · RXN-16002 · not reversible

3-oxo-L-alanine H+
→
2-aminoacetaldehyde CO2
No mapped protein

RXN-16165

EC 6.1.1.10 · RXN-16165 · not reversible

L-methionine initiator tRNAMet ATP
→
an L-methionyl-[initiator tRNAMet] AMP diphosphate
VK055_4963

RXN-16659[CCO-CYTOSOL]-A-DONOR-PG-WITH-MESODAP-PENTAPEPTIDE/AN-ACCEPTOR-PG-WITH-MESODAP-TETRAPEPTIDE//CPD0-2718/D-ALANINE.112.

EC - · RXN-16659[CCO-CYTOSOL]-A-DONOR-PG-WITH-MESODAP-PENTAPEPTIDE/AN-ACCEPTOR-PG-WITH-MESODAP-TETRAPEPTIDE//CPD0-2718/D-ALANINE.112. · not reversible

a donor peptidoglycan with (L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide an acceptor peptidoglycan with (L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide
→
D-alanine a peptidoglycan with D,D cross-links (meso-diaminoepimelate containing)
VK055_0673 VK055_1655 VK055_1865 VK055_1868 VK055_3885 VK055_4951 VK055_5052

RXN-16659[CCO-PERI-BAC]-A-DONOR-PG-WITH-MESODAP-PENTAPEPTIDE/AN-ACCEPTOR-PG-WITH-MESODAP-TETRAPEPTIDE//CPD0-2718/D-ALANINE.113.

EC - · RXN-16659[CCO-PERI-BAC]-A-DONOR-PG-WITH-MESODAP-PENTAPEPTIDE/AN-ACCEPTOR-PG-WITH-MESODAP-TETRAPEPTIDE//CPD0-2718/D-ALANINE.113. · not reversible

a donor peptidoglycan with (L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide an acceptor peptidoglycan with (L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide
→
D-alanine a peptidoglycan with D,D cross-links (meso-diaminoepimelate containing)
VK055_0673 VK055_1655 VK055_1865 VK055_1868 VK055_3885 VK055_4951 VK055_5052

RXN-16664[CCO-CYTOSOL]-CPD-17926/WATER//CPD-17968/D-ALANINE.50.

EC - · RXN-16664[CCO-CYTOSOL]-CPD-17926/WATER//CPD-17968/D-ALANINE.50. · not reversible

a nascent peptidoglycan with (L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide H2O
→
D-alanine a nascent peptidoglycan with (L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimelate) tripeptide
VK055_0146

RXN-16664[CCO-PERI-BAC]-CPD-17926/WATER//CPD-17968/D-ALANINE.51.

EC - · RXN-16664[CCO-PERI-BAC]-CPD-17926/WATER//CPD-17968/D-ALANINE.51. · not reversible

a nascent peptidoglycan with (L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide H2O
→
D-alanine a nascent peptidoglycan with (L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimelate) tripeptide
VK055_0146

RXN-16665[CCO-PERI-BAC]-A-DONOR-PG-WITH-MESODAP-TETRAPEPTIDE/GLY//CPD-17969/D-ALANINE.76.

EC - · RXN-16665[CCO-PERI-BAC]-A-DONOR-PG-WITH-MESODAP-TETRAPEPTIDE/GLY//CPD-17969/D-ALANINE.76. · not reversible

a donor peptidoglycan with (L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide glycine
→
D-alanine a nascent peptidoglycan with (L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-glycine) tetrapeptide
VK055_0325 VK055_1353 VK055_1531 VK055_1678 VK055_2329 VK055_5141

RXN-16765

EC - · RXN-16765 · not reversible

NADPH
→
1,2-dihydro-beta-NADP
No mapped protein

RXN-16804

EC - · RXN-16804 · reversible

aldehydo-D-arabinose 5-phosphate
⇌
D-arabinofuranose 5-phosphate
No mapped protein

RXN-16938

EC 3.5.1.28 · RXN-16938 · not reversible

H2O peptidoglycan dimer with pentapeptide stems (meso-diaminopimelate containing)
→
L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine peptidoglycan dimer with a single pentapeptide stem (meso-diaminopimelate containing)
No mapped protein

RXN-16953

EC 1.1.1.90 · RXN-16953 · reversible

5-(hydroxymethyl)-2-methylphenol NAD+
⇌
3-hydroxy-4-methylbenzaldehyde H+ NADH
VK055_0533

RXN-16954

EC 1.1.1.90 · RXN-16954 · reversible

3-(hydroxymethyl)-5-methylphenol NAD+
⇌
3-hydroxy-5-methylbenzaldehyde H+ NADH
VK055_0533

RXN-17127

EC 6.3.1.20 · RXN-17127 · not reversible

(R)-lipoate a [lipoyl-carrier protein]-L-lysine ATP
→
a [lipoyl-carrier protein]-N6-[(R)-lipoyl]-L-lysine AMP H+ diphosphate
VK055_2590 VK055_5062

RXN-17131

EC 3.9.1.3 · RXN-17131 · not reversible

a [protein]-Npi-phospho-L-histidine H2O
→
a [protein]-L-histidine phosphate
VK055_4791

RXN-17132

EC 3.9.1.3 · RXN-17132 · not reversible

a [protein]-Ntau-phospho-L-histidine H2O
→
a [protein]-L-histidine phosphate
VK055_4791

RXN-17354

EC - · RXN-17354 · not reversible

both
a [PTS enzyme I]-L-histidine phosphoenolpyruvate
→
a [PTS enzyme I]-Npi-phospho-L-histidine pyruvate
VK055_4287

RXN-17355

EC - · RXN-17355 · not reversible

a [PTS enzyme I]-Npi-phospho-L-histidine an [HPr]-L-histidine
→
a [PTS enzyme I]-L-histidine an [HPr protein]-Npi-phospho-L-histidine
VK055_4287

RXN-17392[CCO-CYTOSOL]-CPD-18804//CPD-17986/CPD-18805.44.

EC - · RXN-17392[CCO-CYTOSOL]-CPD-18804//CPD-17986/CPD-18805.44. · not reversible

a peptidoglycan internal segment (with L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine tetrapeptide)
→
a peptidoglycan (meso-DAP containing) with GlcNAc non-reducing terminus a peptidoglycan (meso-DAP containing) with GlcNAc-1,6-anhydro-MurNAc terminus
VK055_0147 VK055_4480

RXN-17392[CCO-PERI-BAC]-CPD-18804//CPD-17986/CPD-18805.45.

EC - · RXN-17392[CCO-PERI-BAC]-CPD-18804//CPD-17986/CPD-18805.45. · not reversible

a peptidoglycan internal segment (with L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine tetrapeptide)
→
a peptidoglycan (meso-DAP containing) with GlcNAc non-reducing terminus a peptidoglycan (meso-DAP containing) with GlcNAc-1,6-anhydro-MurNAc terminus
VK055_0147 VK055_4480

RXN-17473

EC - · RXN-17473 · not reversible

consuming
4,5-secobiotin S-adenosyl-L-methionine
→
5'-deoxyadenosine L-methionine biotin H+
VK055_1731

RXN-17633

EC - · RXN-17633 · not reversible

a [protein]-L-cysteine methylglyoxal
→
an S-(1-hydroxy-2-oxopropyl)-[protein]-L-cysteine
No mapped protein

RXN-17752

EC - · RXN-17752 · not reversible

3-oxo-5,6-didehydrosuberyl-CoA semialdehyde
→
2-hydroxycyclohepta-1,4,6-triene-1-carboxyl-CoA H2O
No mapped protein

RXN-17753

EC - · RXN-17753 · not reversible

carbamoyl phosphate
→
cyanate H+ phosphate
No mapped protein

RXN-17754

EC - · RXN-17754 · not reversible

melibionate H2O
→
D-gluconate alpha-D-galactopyranose
VK055_3274

RXN-17775

EC 1.3.8.8 · RXN-17775 · reversible

an oxidized electron-transfer flavoprotein oleoyl-CoA H+
⇌
(2E,9Z)-octadec-2,9-enoyl-CoA a reduced electron-transfer flavoprotein
No mapped protein

RXN-17777

EC 1.1.1.35 · RXN-17777 · reversible

(S)-3-hydroxy-(9Z)-octadecenoyl-CoA NAD+
⇌
3-oxo-(9Z)-octadecenoyl-CoA H+ NADH
No mapped protein

RXN-17779

EC 1.3.8.8 · RXN-17779 · reversible

(7Z)-hexadecenoyl-CoA an oxidized electron-transfer flavoprotein H+
⇌
(2E,7Z)-hexadec-2,7-dienoyl-CoA a reduced electron-transfer flavoprotein
No mapped protein

RXN-17781

EC 1.1.1.35 · RXN-17781 · reversible

(S)-3-hydroxy-(7Z)-hexadecenoyl-CoA NAD+
⇌
3-oxo-(7Z)-hexadecenoyl-CoA H+ NADH
No mapped protein

RXN-17783

EC 1.3.8.8 · RXN-17783 · reversible

(5Z)-tetradecenoyl-CoA an oxidized electron-transfer flavoprotein H+
⇌
(2E,5Z)-tetradec-2,5-enoyl-CoA a reduced electron-transfer flavoprotein
No mapped protein

RXN-17809

EC 4.6.1.17 · RXN-17809 · not reversible

(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate
→
cyclic pyranopterin phosphate diphosphate
No mapped protein

RXN-17830

EC 3.2.1.22 · RXN-17830 · not reversible

4-nitrophenyl-alpha-D-galactopyranoside H2O
→
4-nitrophenol D-galactopyranose H+
VK055_3274

RXN-17846

EC 2.3.2.6 · RXN-17846 · not reversible

an L-leucyl-[tRNALeu] an N-terminal arginyl-[protein]
→
a [protein] N-terminal L-leucyl-L-arginine a tRNALeu H+
VK055_1569

RXN-17880

EC - · RXN-17880 · not reversible

a [protein]-L-cysteine nitric oxide dioxygen
→
a [protein] 3-nitrosothio-L-alanine superoxide H+
No mapped protein

RXN-17881

EC - · RXN-17881 · not reversible

an N-terminal L-cysteinyl-[protein] hydrogen peroxide
→
an N-terminal 3-sulfeno-L-alanyl-[protein] H2O
No mapped protein

RXN-17882

EC - · RXN-17882 · not reversible

an N-terminal 3-sulfeno-L-alanyl-[protein] hydrogen peroxide
→
an N-terminal 3-sulfino-L-alanyl-[protein] H2O
No mapped protein

RXN-17883

EC - · RXN-17883 · not reversible

an N-terminal 3-sulfino-L-alanyl-[protein] hydrogen peroxide
→
an N-terminal 3-sulfo-L-alanyl-[protein] H+ H2O
No mapped protein

RXN-17884

EC 1.1.1.284 · RXN-17884 · not reversible

producing
S-nitrosoglutathione H+ NADH
→
S-(hydroxysulfenamide)glutathione NAD+
VK055_0526

RXN-17886

EC - · RXN-17886 · not reversible

S-(hydroxysulfenamide)glutathione glutathione
→
glutathione disulfide hydroxylamine
No mapped protein

RXN-17887

EC - · RXN-17887 · reversible

a [protein] 3-nitrosothio-L-alanine glutathione
⇌
S-nitrosoglutathione a [protein]-L-cysteine
No mapped protein

RXN-17900

EC - · RXN-17900 · not reversible

phosphoribulosylformimino-AICAR-phosphate ammonia
→
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide D-erythro-1-(imidazol-4-yl)-glycerol 3-phosphate H2O
VK055_5039 VK055_5041

RXN-17920

EC - · RXN-17920 · not reversible

both
a [DNA ligase]-L-lysine NAD+
→
a [DNA ligase]-N6-(5'-adenylyl)-L-lysine beta-nicotinamide D-ribonucleotide H+
VK055_3473 VK055_4754

RXN-17954

EC 2.7.8.37 · RXN-17954 · not reversible

both
(acetamidomethyl)phosphonate ATP
→
adenine alpha-D-ribose 1-(acetamidomethylphosphonate) 5-triphosphate
VK055_2967 VK055_2968 VK055_2972

RXN-17955

EC 3.6.1.63 · RXN-17955 · not reversible

alpha-D-ribose 1-(acetamidomethylphosphonate) 5-triphosphate H2O
→
alpha-D-ribose-1-(2-N-acetamidomethylphosphonate) 5-phosphate H+ diphosphate
No mapped protein

RXN-17956

EC 4.7.1.1 · RXN-17956 · not reversible

S-adenosyl-L-methionine a reduced two electron carrier alpha-D-ribose-1-(2-N-acetamidomethylphosphonate) 5-phosphate
→
5'-deoxyadenosine 5-phospho-alpha-D-ribose 1,2-cyclic phosphate L-methionine N-methylacetamide an oxidized electron carrier H+
VK055_2970

RXN-17958

EC 3.6.1.63 · RXN-17958 · not reversible

alpha-D-ribose-1-[N-(phosphonomethyl)glycine] 5-triphosphate H2O
→
alpha-D-ribose-1-[N-(phosphonomethyl)glycine] 5-phosphate H+ diphosphate
No mapped protein

RXN-17959

EC 4.7.1.1 · RXN-17959 · not reversible

S-adenosyl-L-methionine a reduced two electron carrier alpha-D-ribose-1-[N-(phosphonomethyl)glycine] 5-phosphate
→
5'-deoxyadenosine 5-phospho-alpha-D-ribose 1,2-cyclic phosphate L-methionine an oxidized electron carrier sarcosine
No mapped protein

RXN-18031

EC - · RXN-18031 · reversible

carbonic acid
⇌
hydrogen carbonate H+
No mapped protein

RXN-18032

EC - · RXN-18032 · reversible

hydrogen carbonate
⇌
carbonate H+
No mapped protein

RXN-18157

EC - · RXN-18157 · reversible

isocyanurate
⇌
cyanuric acid
No mapped protein

RXN-18200

EC - · RXN-18200 · reversible

3-[(7'-methylsulfanyl)heptyl]malate NAD+
⇌
3-carboxy-10-(methylsulfanyl)-2-oxodecanoate H+ NADH
VK055_2494 VK055_4376

RXN-18201

EC - · RXN-18201 · not reversible

3-carboxy-10-(methylsulfanyl)-2-oxodecanoate H+
→
10-(methylsulfanyl)-2-oxodecanoate CO2
No mapped protein

RXN-18202

EC - · RXN-18202 · reversible

3-[(6'-methylsulfanyl)hexyl]malate NAD+
⇌
3-carboxy-9-(methylsulfanyl)-2-oxononanoate H+ NADH
VK055_2494 VK055_4376

RXN-18203

EC - · RXN-18203 · not reversible

3-carboxy-9-(methylsulfanyl)-2-oxononanoate H+
→
9-(methylsulfanyl)-2-oxononanoate CO2
No mapped protein

RXN-18204

EC - · RXN-18204 · reversible

3-[(5'-methylsulfanyl)pentyl]malate NAD+
⇌
3-carboxy-8-(methylsulfanyl)-2-oxooctanoate H+ NADH
VK055_2494 VK055_4376

RXN-18205

EC - · RXN-18205 · not reversible

3-carboxy-8-(methylsulfanyl)-2-oxooctanoate H+
→
8-(methylsulfanyl)-2-oxooctanoate CO2
No mapped protein

RXN-18206

EC - · RXN-18206 · reversible

3-[(4'-methylsulfanyl)butyl]malate NAD+
⇌
3-carboxy-7-(methylsulfanyl)-2-oxoheptanoate H+ NADH
VK055_2494 VK055_4376

RXN-18207

EC - · RXN-18207 · not reversible

3-carboxy-7-(methylsulfanyl)-2-oxoheptanoate H+
→
7-(methylsulfanyl)-2-oxoheptanoate CO2
No mapped protein

RXN-18208

EC - · RXN-18208 · reversible

3-[(3'-methylsulfanyl)propyl]malate NAD+
⇌
3-carboxy-6-(methylsulfanyl)-2-oxohexanoate H+ NADH
VK055_2494 VK055_4376

RXN-18209

EC - · RXN-18209 · not reversible

3-carboxy-6-(methylsulfanyl)-2-oxohexanoate H+
→
6-(methylsulfanyl)-2-oxohexanoate CO2
No mapped protein

RXN-18211

EC - · RXN-18211 · not reversible

3-ethyl-2-oxosuccinate H+
→
2-oxovalerate CO2
No mapped protein

RXN-18232

EC - · RXN-18232 · reversible

thiocyanate
⇌
isothiocyanate
No mapped protein

RXN-18356

EC - · RXN-18356 · not reversible

3-sulfino-L-alanine H2O NAD+
→
L-cysteate H+ NADH
No mapped protein

RXN-18392

EC - · RXN-18392 · reversible

2-dehydro-3-deoxy-D-octonate
⇌
3-deoxy-alpha-D-manno-2-octulosonate
No mapped protein

RXN-18434

EC 2.3.1.267 · RXN-18434 · not reversible

acetyl-CoA an N-terminal L-alanyl-[uS5 protein of 30S ribosome]
→
an N-terminal N-acetyl-L-alanyl-[uS5 protein of 30S ribosome] H+ coenzyme A
VK055_1388 VK055_2602

RXN-18446

EC 6.2.1.1 · RXN-18446 · not reversible

producing
3-methylbutanoate ATP coenzyme A
→
3-methylbutanoyl-CoA AMP diphosphate
VK055_2990

RXN-18447

EC 6.2.1.1 · RXN-18447 · not reversible

isobutanoate ATP coenzyme A
→
isobutanoyl-CoA AMP diphosphate
VK055_2990

RXN-18448

EC 6.2.1.1 · RXN-18448 · not reversible

2-methylbutanoate ATP coenzyme A
→
(2S)-2-methylbutanoyl-CoA AMP diphosphate
VK055_2990

RXN-18455

EC 2.7.7.- · RXN-18455 · not reversible

a TtuB sulfur-carrier protein ATP H+
→
a carboxyadenylated [TtuB sulfur-carrier protein] diphosphate
No mapped protein

RXN-18456

EC 2.8.1.- · RXN-18456 · not reversible

a [TtuD protein]-S-sulfanyl-L-cysteine a carboxyadenylated [TtuB sulfur-carrier protein] a reduced two electron carrier
→
a [TtuD protein]-L-cysteine a thiocarboxylated [TtuB sulfur-carrier protein] an oxidized electron carrier AMP H+
No mapped protein

RXN-18457

EC 2.8.1.15 · RXN-18457 · not reversible

a 5-methyluracil54 in tRNA a thiocarboxylated [TtuB sulfur-carrier protein] ATP H2O
→
a 5-methyl-2-thiouracil54 in tRNA a TtuB sulfur-carrier protein AMP H+ diphosphate
No mapped protein

RXN-18510

EC 2.7.1.26 · RXN-18510 · not reversible

roseoflavin ATP
→
roseoflavin 5'-phosphate ADP H+
VK055_2555

RXN-18513

EC - · RXN-18513 · not reversible

2-deoxy-D-glucono-1,5-lactone H2O
→
2-deoxy-D-gluconate H+
No mapped protein

RXN-18514

EC 1.1.3.4 · RXN-18514 · not reversible

2-deoxy-D-glucose dioxygen
→
2-deoxy-D-glucono-1,5-lactone hydrogen peroxide
No mapped protein

RXN-18586

EC - · RXN-18586 · not reversible

S-sulfo-L-cysteine a reduced glutaredoxin
→
L-cysteine an oxidized glutaredoxin sulfite H+
No mapped protein

RXN-18602

EC 2.5.1.48 · RXN-18602 · reversible

O-succinyl-L-homoserine methanethiol
⇌
L-methionine succinate H+
VK055_3243

RXN-18702

EC - · RXN-18702 · not reversible

2-oxo-3-sulfanylpropanoate a [3-mercaptopyruvate sulfurtransferase]-L-cysteine
→
a [3-mercaptopyruvate sulfurtransferase]-S-sulfanyl-L-cysteine pyruvate
VK055_4649

RXN-18705

EC 2.8.1.- · RXN-18705 · not reversible

a [3-mercaptopyruvate sulfurtransferase]-L-cysteine an [L-cysteine desulfurase]-S-sulfanyl-L-cysteine
→
a [3-mercaptopyruvate sulfurtransferase]-S-sulfanyl-L-cysteine an [L-cysteine desulfurase]-L-cysteine
VK055_4649

RXN-18707

EC - · RXN-18707 · not reversible

a [TusA]-L-cysteine an [L-cysteine desulfurase]-S-sulfanyl-L-cysteine
→
a [TusA sulfur-carrier protein]-S-sulfanyl-L-cysteine an [L-cysteine desulfurase]-L-cysteine
VK055_0323 VK055_4349 VK055_4350 VK055_4639

RXN-18708

EC 2.8.1.- · RXN-18708 · not reversible

a [TusD sulfur-carrier protein]-S-sulfanyl-L-cysteine a [TusE sulfur carrier protein]-L-cysteine
→
a [TusD]-L-cysteine a [TusE sulfur carrier protein]-S-sulfanylcysteine
No mapped protein

RXN-18709

EC 2.8.1.- · RXN-18709 · not reversible

a [TusA sulfur-carrier protein]-S-sulfanyl-L-cysteine a [TusD]-L-cysteine
→
a [TusA]-L-cysteine a [TusD sulfur-carrier protein]-S-sulfanyl-L-cysteine
No mapped protein

RXN-18710

EC - · RXN-18710 · not reversible

a 2-thiouridine34 in tRNA a 5,10-methylenetetrahydrofolate an oxidized electron carrier glycine GTP H2O
→
a 5-carboxymethylaminomethyl-2-thiouridine34 in tRNA a 7,8-dihydrofolate a reduced two electron carrier GDP H+ phosphate
No mapped protein

RXN-18770

EC - · RXN-18770 · not reversible

a [TtuD protein]-L-cysteine an [L-cysteine desulfurase]-S-sulfanyl-L-cysteine
→
a [TtuD protein]-S-sulfanyl-L-cysteine an [L-cysteine desulfurase]-L-cysteine
VK055_0323 VK055_4349 VK055_4350 VK055_4639

RXN-18804

EC - · RXN-18804 · not reversible

producing
L-glutamate ATP H+
→
(L-glutamyl)adenylate diphosphate
VK055_4762

RXN-18819

EC - · RXN-18819 · not reversible

D-ribose glycine
→
glycine norfuraneol H2O
No mapped protein

RXN-18951

EC 1.4.3.21 · RXN-18951 · not reversible

benzylamine H2O dioxygen
→
benzaldehyde ammonium hydrogen peroxide
VK055_1043

RXN-19022

EC - · RXN-19022 · not reversible

gamma-L-glutamyl 5-phosphate
→
5-oxo-L-proline H+ phosphate
No mapped protein

RXN-19024

EC 4.3.2.7 · RXN-19024 · not reversible

glutathione
→
5-oxo-L-proline L-cysteinylglycine
No mapped protein

RXN-19079

EC - · RXN-19079 · not reversible

producing
L-proline ATP H+
→
(L-prolyl)adenylate diphosphate
VK055_2358

RXN-19145

EC 2.3.2.5 · RXN-19145 · not reversible

a [protein] with an N-terminal L-glutamine
→
a [protein] with an N-terminal 5-oxo-L-proline ammonium
No mapped protein

RXN-19146

EC - · RXN-19146 · not reversible

a [protein] with an N-terminal L-glutamate
→
a [protein] with an N-terminal 5-oxo-L-proline H2O
No mapped protein

RXN-19250

EC 1.5.1.21 · RXN-19250 · not reversible

1-piperideine-2-carboxylate H+ NADPH
→
L-pipecolate NADP+
VK055_2646

RXN-19295

EC 2.4.2.21 · RXN-19295 · not reversible

adenine beta-nicotinate D-ribonucleotide
→
adenine ribotide phosphate nicotinate H+
VK055_4344 VK055_5057

RXN-19298

EC 2.4.2.21 · RXN-19298 · not reversible

producing
benzimidazole beta-nicotinate D-ribonucleotide
→
benzimidazole ribotide phosphate nicotinate H+
VK055_4344 VK055_5057

RXN-19299

EC 2.4.2.21 · RXN-19299 · not reversible

5-hydroxybenzimidazole beta-nicotinate D-ribonucleotide
→
5-hydroxybenzimidazole ribotide phosphate nicotinate H+
VK055_4344 VK055_5057

RXN-19300

EC 2.4.2.21 · RXN-19300 · not reversible

5-methoxybenzimidazole beta-nicotinate D-ribonucleotide
→
5-methoxybenzimidazole ribotide phosphate nicotinate H+
VK055_4344 VK055_5057

RXN-19301

EC 2.4.2.21 · RXN-19301 · not reversible

5-methoxy-6-methylbenzimidazole beta-nicotinate D-ribonucleotide
→
5-methoxy-6-methylbenzimidazole ribotide phosphate nicotinate H+
VK055_4344 VK055_5057

RXN-19302

EC 2.7.8.26 · RXN-19302 · not reversible

both
adenosylcobinamide-GDP benzimidazole ribotide phosphate
→
Coalpha-[alpha-(benzimidazolyl)]-Cobeta-adenosylcobamide 5'-phosphate GMP H+
VK055_5056

RXN-19305

EC 2.7.8.26 · RXN-19305 · not reversible

5-methoxy-6-methylbenzimidazole ribotide phosphate adenosylcobinamide-GDP
→
Coalpha-[alpha-(5-methoxy-6-methylbenzimidazolyl)]-Cobeta-adenosylcobamide 5'-phosphate GMP H+
VK055_5056

RXN-19306

EC 2.4.2.21 · RXN-19306 · not reversible

5-methylbenzimidazole beta-nicotinate D-ribonucleotide
→
5-methylbenzimidazole ribotide phosphate nicotinate H+
VK055_4344 VK055_5057

RXN-19307

EC 2.7.8.26 · RXN-19307 · not reversible

5-methylbenzimidazole ribotide phosphate adenosylcobinamide-GDP
→
Coalpha-[alpha-(5-methylbenzimidazolyl)]-Cobeta-adenosylcobamide 5'-phosphate GMP H+
VK055_5056

RXN-19308

EC 2.7.8.26 · RXN-19308 · not reversible

adenine ribotide phosphate adenosylcobinamide-GDP
→
Coalpha-[alpha-(adenin-9-yl)]-Cobeta-adenosylcobamide 5'-phosphate GMP H+
VK055_5056

RXN-19310

EC 3.1.3.73 · RXN-19310 · not reversible

Coalpha-[alpha-(adenin-9-yl)]-Cobeta-adenosylcobamide 5'-phosphate H2O
→
Coalpha-[alpha-(adenin-7-yl)]-Cobeta-adenosylcobamide phosphate
VK055_1862

RXN-19313

EC 3.1.3.73 · RXN-19313 · not reversible

both
5-hydroxybenzimidazole ribotide phosphate H2O
→
5-hydroxybenzimidazole ribotide phosphate
VK055_1862

RXN-19316

EC 2.4.2.21 · RXN-19316 · not reversible

2-methyladenine beta-nicotinate D-ribonucleotide
→
2-methyladenine ribotide phosphate nicotinate H+
VK055_4344 VK055_5057

RXN-19318

EC 2.7.8.26 · RXN-19318 · not reversible

2-methyladenine ribotide phosphate adenosylcobinamide-GDP
→
Coalpha-[alpha-(2-methyladenin-9-yl)]-Cobeta-adenosylcobamide 5'-phosphate GMP H+
VK055_5056

RXN-19319

EC 3.1.3.73 · RXN-19319 · not reversible

Coalpha-[alpha-(2-methyladenin-9-yl)]-Cobeta-adenosylcobamide 5'-phosphate H2O
→
Coalpha-[alpha-(2-methyladenin-7-yl)]-Cobeta-adenosylcobamide phosphate
VK055_1862

RXN-19322

EC 3.1.3.73 · RXN-19322 · not reversible

Coalpha-[alpha-(5-methoxy-6-methylbenzimidazolyl)]-Cobeta-adenosylcobamide 5'-phosphate H2O
→
Coalpha-[alpha-(5-methoxy-6-methyl-benzimidazolyl)]-Cobeta-adenosylcobamide phosphate
VK055_1862

RXN-19324

EC 3.1.3.73 · RXN-19324 · not reversible

Coalpha-[alpha-(5-methylbenzimidazolyl)]-Cobeta-adenosylcobamide 5'-phosphate H2O
→
Coalpha-[alpha-(5-methylbenzimidazolyl)]-Cobeta-adenosylcobamide phosphate
VK055_1862

RXN-19326

EC 3.1.3.73 · RXN-19326 · not reversible

Coalpha-[alpha-(benzimidazolyl)]-Cobeta-adenosylcobamide 5'-phosphate H2O
→
Coalpha-[alpha-(benzimidazolyl)]-Cobeta-adenosylcobamide phosphate
VK055_1862

RXN-19329

EC 1.5.1.3 · RXN-19329 · not reversible

7,8-dihydrofolate monoglutamate H+ NADPH
→
5,6,7,8-tetrahydrofolate NADP+
VK055_2529

RXN-19334

EC - · RXN-19334 · not reversible

a [reduced flavoprotein] cob(II)alamin-[corrinoid adenosyltranferase]
→
an [oxidized flavoprotein] cob(I)alamin-[corrinoid adenosyltranferase] H+
No mapped protein

RXN-19338

EC - · RXN-19338 · not reversible

[corrinoid adenosyltranferase]-cob(II)inamide a [reduced flavoprotein]
→
[corrinoid adenosyltranferase]-cob(I)inamide an [oxidized flavoprotein] H+
No mapped protein

RXN-19341

EC - · RXN-19341 · not reversible

an [oxidized flavoprotein] cob(I)alamin H+
→
a [reduced flavoprotein] cob(II)alamin
No mapped protein

RXN-19343

EC - · RXN-19343 · not reversible

consuming
[corrinoid adenosyltranferase]-cob(I)inamide ATP H+
→
a [corrinoid adenosyltransferase] adenosylcobinamide triphosphate
VK055_1187 VK055_3976 VK055_4310

RXN-19344

EC - · RXN-19344 · not reversible

producing
a [corrinoid adenosyltransferase] cob(II)yrinate a,c-diamide
→
cob(II)yrinate a,c-diamide-[corrinoid adenosyltranferase]
VK055_1187 VK055_3976 VK055_4310

RXN-19492

EC - · RXN-19492 · reversible

(2E)-2-hydroxypenta-2,4-dienoate
⇌
2-oxopent-4-enoate
VK055_0588

RXN-19498

EC - · RXN-19498 · not reversible

producing
L-arginine ATP H+
→
(L-arginyl)adenylate diphosphate
VK055_0059

RXN-19524

EC 2.3.1.5 · RXN-19524 · not reversible

5-aminosalicylate acetyl-CoA
→
N-acetyl-5-aminosalicylate coenzyme A
VK055_0599

RXN-19612

EC - · RXN-19612 · not reversible

S-(2-chlorocarboxymethyl)-glutathione H2O
→
chloride glutathione glyoxylate H+
No mapped protein

RXN-19659

EC - · RXN-19659 · reversible

carbamate H+ H2O
⇌
hydrogen carbonate ammonium
No mapped protein

RXN-19757

EC 3.2.1.55 · RXN-19757 · not reversible

consuming
an alpha(1,5)-L-arabinan with alpha(1,3) branching H2O
→
a (1,5)-alpha-L-arabinan alpha-L-arabinofuranose
VK055_2457

RXN-19758

EC 3.2.1.55 · RXN-19758 · not reversible

producing
an alpha(1,5)-L-arabinan with alpha(1,2) and alpha(1,3) branching H2O
→
alpha-L-arabinofuranose an alpha(1,5)-L-arabinan with alpha(1,3) branching
VK055_2457

RXN-19769

EC 3.2.1.55 · RXN-19769 · not reversible

p-nitrophenyl-alpha-L-arabinofuranoside H2O
→
4-nitrophenol alpha-L-arabinofuranose H+
VK055_2457

RXN1G-1435

EC 3.1.3.12 · RXN1G-1435 · not reversible

6-O-alpha-mycolyl-trehalose 6-phosphate H2O
→
alpha, alpha'-trehalose 6-alpha-mycolate phosphate
VK055_0054

RXN1G-1436

EC 3.1.3.12 · RXN1G-1436 · not reversible

6-O-cis-methoxy-mycolyl-trehalose 6-phosphate H2O
→
trehalose-cis-methoxy-mono-mycolate phosphate
VK055_0054

RXN1G-1437

EC 3.1.3.12 · RXN1G-1437 · not reversible

6-O-trans-methoxy-mycolyl-trehalose 6-phosphate H2O
→
trehalose-trans-methoxy-mono-mycolate phosphate
VK055_0054

RXN1G-1438

EC 3.1.3.12 · RXN1G-1438 · not reversible

6-O-cis-keto-mycolyl-trehalose 6-phosphate H2O
→
trehalose-cis-keto-mono-mycolate phosphate
VK055_0054

RXN1G-1439

EC 3.1.3.12 · RXN1G-1439 · not reversible

6-O-trans-keto-mycolyl-trehalose 6-phosphate H2O
→
trehalose-trans-keto-mono-mycolate phosphate
VK055_0054

RXN1YI0-14

EC 1.3.5.1 · RXN1YI0-14 · reversible

a plastoquinone succinate
⇌
a plastoquinol fumarate
VK055_0048

RXN1ZN3-10

EC - · RXN1ZN3-10 · not reversible

consuming
(7R,8S)-8-amino-7-(carboxyamino)nonanoate ATP
→
dethiobiotin ADP H+ phosphate
VK055_0924 VK055_1728

RXN1ZN3-9

EC - · RXN1ZN3-9 · not reversible

producing
(7R,8S)-diaminononanoate CO2
→
(7R,8S)-8-amino-7-(carboxyamino)nonanoate H+
VK055_0924 VK055_1728

RXN-2003

EC 1.1.1.35 · RXN-2003 · reversible

(S)-3-hydroxy-3-phenylpropanoyl-CoA NAD+
⇌
3-oxo-3-phenylpropanoyl-CoA H+ NADH
No mapped protein

RXN-20077

EC - · RXN-20077 · not reversible

3-hydroxypropanal
→
3-hydroxypropanal dimer
No mapped protein

RXN-20079

EC - · RXN-20079 · not reversible

3-hydroxypropanal H2O
→
3-hydroxypropanal hydrate
No mapped protein

RXN-20084

EC - · RXN-20084 · not reversible

2-oxoglutarate H+ NADPH ammonia
→
L-glutamate H2O NADP+
No mapped protein

RXN-20150

EC - · RXN-20150 · not reversible

producing
a 3-oxoacyl-CoA a [protein]-L-cysteine
→
a [protein] S-acyl-L-cysteine acetyl-CoA
VK055_3136 VK055_4789

RXN-20152

EC - · RXN-20152 · not reversible

consuming
a [protein] S-acyl-L-cysteine coenzyme A
→
a [protein]-L-cysteine an acyl-CoA
VK055_3136 VK055_4789

RXN-20165

EC 3.1.6.1 · RXN-20165 · not reversible

4-nitrocatecholsulfate H2O
→
4-nitrocatechol sulfate H+
VK055_2016

RXN-20178

EC 1.8.98.7 · RXN-20178 · not reversible

S-adenosyl-L-methionine a [sulfatase]-L-cysteine H2O
→
5'-deoxyadenosine L-methionine a [sulfatase]-3-oxo-L-alanine hydrogen sulfide H+
VK055_2015 VK055_4678

RXN-20400

EC 6.3.2.2 · RXN-20400 · not reversible

(S)-2-aminobutanoate L-glutamate ATP
→
gamma-L-glutamyl-(S)-2-aminobutanoate ADP H+ phosphate
VK055_4497

RXN-20401

EC 6.3.2.3 · RXN-20401 · not reversible

gamma-L-glutamyl-(S)-2-aminobutanoate glycine ATP
→
ophthalmate ADP H+ phosphate
VK055_4099

RXN-20406

EC 6.3.2.2 · RXN-20406 · not reversible

L-alanine L-glutamate ATP
→
gamma-L-glutamyl-D-alanine ADP H+ phosphate
VK055_4497

RXN-20407

EC 6.3.2.3 · RXN-20407 · not reversible

gamma-L-glutamyl-L-alanine glycine ATP
→
norophthalmate ADP H+ phosphate
VK055_4099

RXN-20456

EC - · RXN-20456 · not reversible

H2O NADPH
→
(R)-NADPHX
No mapped protein

RXN-20457

EC - · RXN-20457 · not reversible

H2O NADPH
→
(S)-NADPHX
No mapped protein

RXN-20459

EC - · RXN-20459 · reversible

S-adenosyl-L-methionine
⇌
(R)-S-adenosyl-L-methionine
No mapped protein

RXN-20524

EC 2.7.7.41 · RXN-20524 · not reversible

a 1-acyl-2-arachidonoyl-sn-glycerol 3-phosphate CTP H+
→
a CDP-1-acyl-2-arachidonoyl-glycerol diphosphate
VK055_0972

RXN-20556

EC 3.1.4.46 · RXN-20556 · not reversible

sn-glycero-3-phospho-N-(arachidonoyl)ethanolamine H2O
→
anandamide sn-glycerol 3-phosphate H+
VK055_3661 VK055_4870

RXN-20673

EC - · RXN-20673 · not reversible

producing
3-deoxy-D-arabino-heptulosonate 7-phosphate
→
3-deoxy-D-arabino-heptulopyranuronate 7-phosphate
VK055_3710

RXN-20674

EC - · RXN-20674 · not reversible

consuming
3-deoxy-D-arabino-heptulopyranuronate 7-phosphate
→
3-dehydroquinate phosphate
VK055_3710

RXN-20675

EC 4.2.1.74 · RXN-20675 · reversible

(S)-3-hydroxydodecanoyl-CoA
⇌
(2E)-dodec-2-enoyl-CoA H2O
No mapped protein

RXN-20676

EC 1.1.1.211, 1.1.1.35 · RXN-20676 · reversible

(S)-3-hydroxydodecanoyl-CoA NAD+
⇌
3-oxododecanoyl-CoA H+ NADH
No mapped protein

RXN-20678

EC 4.2.1.74 · RXN-20678 · reversible

(3S)-3-hydroxyoctanoyl-CoA
⇌
(2E)-oct-2-enoyl-CoA H2O
No mapped protein

RXN-20679

EC 1.1.1.35 · RXN-20679 · reversible

(3S)-3-hydroxyoctanoyl-CoA NAD+
⇌
3-oxooctanoyl-CoA H+ NADH
No mapped protein

RXN-20680

EC 1.1.1.- · RXN-20680 · not reversible

a D-guloside NAD+
→
a 3-dehydro-D-guloside H+ NADH
VK055_3441

RXN-20681

EC - · RXN-20681 · reversible

a 3-dehydro-D-guloside
⇌
a 3-dehydro-D-glucoside
No mapped protein

RXN-20682

EC 1.1.1.- · RXN-20682 · not reversible

a 3-dehydro-D-glucoside H+ NADH
→
a D-glucoside NAD+
No mapped protein

RXN-20690

EC 1.11.1.28 · RXN-20690 · not reversible

a [lipoyl-carrier protein]-N6-[(R)-dihydrolipoyl]-L-lysine an organic hydroperoxide
→
a [lipoyl-carrier protein]-N6-[(R)-lipoyl]-L-lysine an alcohol H2O
VK055_1883

RXN-20693

EC 1.11.1.27 · RXN-20693 · not reversible

an organic hydroperoxide glutathione
→
an alcohol glutathione disulfide H2O
VK055_1883

RXN-20694

EC - · RXN-20694 · not reversible

a [1-Cys-peroxiredoxin]-L-cysteine an organic hydroperoxide
→
a [1-Cys-peroxiredoxin]-S-hydroxy-L-cysteine an alcohol
VK055_1883

RXN-20695

EC - · RXN-20695 · not reversible

a [1-Cys-peroxiredoxin]-S-hydroxy-L-cysteine a [glutathione-S-transferase]-(glutathion-S-yl)-L-cysteine a reduced two electron carrier
→
a [1-Cys-peroxiredoxin]-(glutathion-S-yl)-L-cysteine a [glutathione-S-transferase]-L-cysteine an oxidized electron carrier H2O
VK055_1883

RXN-20696

EC - · RXN-20696 · not reversible

consuming
a [1-Cys-peroxiredoxin]-(glutathion-S-yl)-L-cysteine glutathione
→
a [1-Cys-peroxiredoxin]-L-cysteine glutathione disulfide
VK055_1883

RXN-20697

EC - · RXN-20697 · not reversible

both
a [glutathione-S-transferase]-L-cysteine an oxidized electron carrier glutathione
→
a [glutathione-S-transferase]-(glutathion-S-yl)-L-cysteine a reduced two electron carrier
VK055_1883

RXN-20755

EC - · RXN-20755 · not reversible

producing
a 5-[(methylamino)methyl]-2-thiouridine34 in tRNA geranyl diphosphate
→
a 5-methylaminomethyl-2-(S-geranyl)thiouridine34 in tRNA diphosphate
VK055_2071

RXN-20756

EC - · RXN-20756 · not reversible

both
a 5-methylaminomethyl-2-(S-geranyl)thiouridine34 in tRNA selenophosphate
→
(2E)-3,7-dimethylocta-2,6-diene-1-thiol a 5-methylaminomethyl-2-(Se-phospho)selenouridine34 in tRNA
VK055_2071

RXN-20757

EC - · RXN-20757 · not reversible

consuming
a 5-methylaminomethyl-2-(Se-phospho)selenouridine34 in tRNA H2O
→
a 5-methylaminomethyl-2-selenouridine34 in tRNA phosphate
VK055_2071

RXN-20762

EC 2.9.1.3 · RXN-20762 · not reversible

a 5-carboxymethylaminomethyl-2-thiouridine34 in tRNA geranyl diphosphate selenophosphate H2O
→
(2E)-3,7-dimethylocta-2,6-diene-1-thiol a 5-carboxymethylaminomethyl-2-selenouridine34 in tRNA diphosphate phosphate
VK055_2071

RXN-20764

EC 4.2.1.80 · RXN-20764 · not reversible

(2Z)-2-hydroxyhexa-2,5-dienoate H2O
→
(S)-4-hydroxy-2-oxohexanoate
VK055_0342

RXN-20784

EC 2.7.1.130 · RXN-20784 · not reversible

consuming
lipid A disaccharide (P. putida) ATP
→
lipid IVA (P. putida) ADP H+
VK055_1542

RXN-20785

EC 2.4.1.182 · RXN-20785 · not reversible

both
UDP-2-N-[(3R)-3-hydroxydodecanoyl]-3-O-[(3R)-3-hydroxydecanoyl]-alpha-D-glucosamine lipid X (P. putida)
→
lipid A disaccharide (P. putida) H+ UDP
VK055_2370

RXN-20786

EC 3.6.1.54 · RXN-20786 · not reversible

UDP-2-N-[(3R)-3-hydroxydodecanoyl]-3-O-[(3R)-3-hydroxydecanoyl]-alpha-D-glucosamine H2O
→
lipid X (P. putida) H+ UMP
VK055_2067

RXN-20898

EC - · RXN-20898 · not reversible

L-lysine aldehydo-D-glucose
→
N6-(1-deoxy-D-fructos-1-yl)-L-lysine H2O
No mapped protein

RXN-21019

EC - · RXN-21019 · not reversible

arsenous acid glutathione
→
arsenic triglutathione H2O
No mapped protein

RXN-21024

EC - · RXN-21024 · not reversible

an [arsenate reductase]-L-cysteine arsenate H+
→
thiarsahydroxy-[arsenate reductase] H2O
VK055_4217 VK055_4693

RXN-21025

EC - · RXN-21025 · not reversible

both
glutathione thiarsahydroxy-[arsenate reductase] H+
→
S-glutathionyl-thiarsahydroxy-[arsenate reductase] H2O
VK055_4217 VK055_4693

RXN-21027

EC - · RXN-21027 · not reversible

S-arsorososulfanethiol-[arsenate reductase] H2O
→
an [arsenate reductase]-L-cysteine arsenite H+
VK055_4217 VK055_4693

RXN-21080

EC - · RXN-21080 · not reversible

an [HPr]-L-histidine phosphoenolpyruvate
→
an [HPr protein]-Npi-phospho-L-histidine pyruvate
No mapped protein

RXN-21104

EC - · RXN-21104 · not reversible

producing
L-asparagine ATP H+
→
(L-asparaginyl)adenylate diphosphate
VK055_1526

RXN-21230

EC - · RXN-21230 · not reversible

6,7-dihydrobiopterin
→
a 7,8-dihydrobiopterin
No mapped protein

RXN-21315

EC 5.3.1.23 · RXN-21315 · reversible

5-deoxy-alpha-D-ribose 1-phosphate
⇌
5-deoxy-D-ribulose 1-phosphate
VK055_1907

RXN-21317

EC 2.7.1.100 · RXN-21317 · not reversible

5-deoxy-D-ribofuranose ATP
→
5-deoxy-alpha-D-ribose 1-phosphate ADP H+
VK055_1908

RXN-21432

EC 3.2.1.52 · RXN-21432 · not reversible

N-acetyl-beta-D-glucosaminyl-(1 -> 4)-N-acetyl-D-muramate H2O
→
N-acetyl-D-glucosamine N-acetyl-D-muramate
VK055_1361

RXN-21522

EC - · RXN-21522 · not reversible

an apo-[hydroxymethylbilane synthase]-L-cysteine preuroporphyrinogen
→
a [hydroxymethylbilane synthase] ES2 intermediate H2O
No mapped protein

RXN-21523

EC - · RXN-21523 · not reversible

a [hydroxymethylbilane synthase] ES2 intermediate porphobilinogen
→
a [hydroxymethylbilane synthase] ES3 intermediate ammonium
VK055_3171

RXN-21524

EC - · RXN-21524 · not reversible

a [hydroxymethylbilane synthase] ES3 intermediate porphobilinogen
→
a [hydroxymethylbilane synthase] ES4 intermediate ammonium
VK055_3171

RXN-21525

EC - · RXN-21525 · not reversible

both
a [hydroxymethylbilane synthase] ES4 intermediate H2O
→
a holo-[hydroxymethylbilane synthase] preuroporphyrinogen
VK055_3171

RXN-21526

EC - · RXN-21526 · not reversible

a holo-[hydroxymethylbilane synthase] porphobilinogen
→
a holo [hydroxymethylbilane synthase] ES intermediate ammonium
VK055_3171

RXN-21527

EC - · RXN-21527 · not reversible

consuming
a holo [hydroxymethylbilane synthase] ES intermediate porphobilinogen
→
a [hydroxymethylbilane synthase] ES2 intermediate ammonium
VK055_3171

RXN-21550

EC 2.8.1.- · RXN-21550 · not reversible

a [bis(guanylyl molybdopterin) cofactor chaperone]-S-sulfanyl-L-cysteine a [bis(guanylyl molybdopterin) cofactor chaperone]-bis(guanylyl molybdopterin) cofactor a reduced two electron carrier
→
a [bis(guanylyl molybdopterin) cofactor chaperone]-L-cysteine an oxidized electron carrier sulfo-bis(guanylyl molybdopterin) cofactor H2O
No mapped protein

RXN-21560

EC 2.8.1.7 · RXN-21560 · not reversible

consuming
L-cysteine a [cytidylyl molybdenum cofactor chaperone]-cytidylyl MoO2(OH)-molybdopterin cofactor a reduced two electron carrier
→
L-alanine a [cytidylyl molybdenum cofactor chaperone]-cytidylyl MoO2(S)-molybdenum cofactor an oxidized electron carrier H2O
VK055_0323 VK055_4349 VK055_4350 VK055_4639

RXN-21562

EC - · RXN-21562 · not reversible

a bis(guanylyl molybdopterin) cofactor chaperone bis(guanylyl molybdopterin) cofactor
→
a [bis(guanylyl molybdopterin) cofactor chaperone]-bis(guanylyl molybdopterin) cofactor
No mapped protein

RXN-21565

EC - · RXN-21565 · not reversible

a [bis(guanylyl molybdopterin) cofactor chaperone]-L-cysteine an [L-cysteine desulfurase]-S-sulfanyl-L-cysteine
→
a [bis(guanylyl molybdopterin) cofactor chaperone]-S-sulfanyl-L-cysteine an [L-cysteine desulfurase]-L-cysteine
VK055_0323 VK055_4349 VK055_4350 VK055_4639

RXN-21566

EC 2.8.1.7 · RXN-21566 · not reversible

L-cysteine a [bis(guanylyl molybdopterin) cofactor chaperone]-L-cysteine
→
L-alanine a [bis(guanylyl molybdopterin) cofactor chaperone]-S-sulfanyl-L-cysteine
VK055_0323 VK055_4349 VK055_4350 VK055_4639

RXN-22

EC 4.3.2.1 · RXN-22 · reversible

canavaninosuccinate
⇌
L-canavanine fumarate
VK055_3227

RXN-22002

EC - · RXN-22002 · not reversible

a [biotin carboxyl-carrier protein]-L-lysine biotinyl-5'-adenylate
→
a [biotin carboxyl-carrier protein]-N6-biotinyl-L-lysine AMP H+
No mapped protein

RXN-22064

EC 2.6.1.82 · RXN-22064 · reversible

2-oxoglutarate spermidine
⇌
L-glutamate N-(3-aminopropyl)-4-aminobutanal
VK055_3967

RXN-22237

EC 2.4.1.182 · RXN-22237 · not reversible

UDP-2-N-[(3R)-3-hydroxy-15-methylhexadecanoyl]-3-O-[(3R)-3-hydroxy-13-methyltetradecanoyl]-alpha-D-glucosamine lipid X (P. gingivalis)
→
lipid A disaccharide (P. gingivalis) H+ UDP
VK055_2370

RXN-22238

EC 2.7.1.130 · RXN-22238 · not reversible

both
lipid A disaccharide (P. gingivalis) ATP
→
lipid IVA (P. gingivalis) ADP H+
VK055_1542

RXN-22239

EC 3.6.1.54 · RXN-22239 · not reversible

both
UDP-2-N-[(3R)-3-hydroxy-16-methylhexadecanoyl]-3-O-[(3R)-3-hydroxyhexadecanoyl]-alpha-D-glucosamine H2O
→
lipid X (P. gingivalis) H+ UMP
VK055_2067

RXN-22247

EC 3.5.1.108 · RXN-22247 · not reversible

both
UDP-3-O-[(3R)-3-hydroxyhexanoyl]-N-acetyl-alpha-D-glucosamine H2O
→
UDP-3-O-[(3R)-3-hydroxy-hexadecanoyl]-alpha-D-glucosamine acetate
VK055_2471

RXN-22248

EC 2.4.99.12 · RXN-22248 · not reversible

both
CMP-3-deoxy-beta-D-manno-octulosonate lipid IVA (P. gingivalis)
→
alpha-Kdo-(2->6)-lipid IVA (P. gingivalis) CMP H+
VK055_3497

RXN-22249

EC 2.4.99.13 · RXN-22249 · not reversible

consuming
CMP-3-deoxy-beta-D-manno-octulosonate alpha-Kdo-(2->6)-lipid IVA (P. gingivalis)
→
alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (P. gingivalis) CMP H+
VK055_3497

RXN-22285

EC - · RXN-22285 · reversible

hydrogen selenide
⇌
selenide H+
No mapped protein

RXN-22286

EC - · RXN-22286 · reversible

hydrosulfide H+
⇌
hydrogen sulfide
No mapped protein

RXN-22287

EC - · RXN-22287 · reversible

hydrosulfide
⇌
S2- H+
No mapped protein

RXN-22315

EC - · RXN-22315 · reversible

arsenous acid
⇌
arsenite H+
No mapped protein

RXN-22316

EC - · RXN-22316 · reversible

arsenite
⇌
arsenite2- H+
No mapped protein

RXN-22317

EC - · RXN-22317 · reversible

arsenite2-
⇌
arsenite3- H+
No mapped protein

RXN-22319

EC - · RXN-22319 · reversible

acetic acid
⇌
acetate H+
No mapped protein

RXN-22388

EC - · RXN-22388 · reversible

dihydrogen phosphate
⇌
H+ phosphate
No mapped protein

RXN-22435

EC - · RXN-22435 · not reversible

acetoin an [acetoin dehydrogenase E2 protein] N6-lipoyl-L-lysine
→
acetaldehyde an [acetoin dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine
VK055_2293 VK055_2294

RXN-22436

EC - · RXN-22436 · not reversible

an [acetoin dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine coenzyme A
→
acetyl-CoA an [acetoin dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine
VK055_2293 VK055_2294

RXN-22438

EC 1.5.1.54 · RXN-22438 · reversible

a 5-methyltetrahydrofolate NAD+
⇌
a 5,10-methylenetetrahydrofolate H+ NADH
VK055_3237

RXN-22439

EC - · RXN-22439 · not reversible

(2S)-2-amino-4-deoxy-chorismate ammonia
→
4-amino-4-deoxychorismate ammonia
No mapped protein

RXN-22440

EC 2.6.1.123 · RXN-22440 · not reversible

L-glutamine chorismate H2O
→
4-amino-4-deoxychorismate L-glutamate H+ ammonia
No mapped protein

RXN-22462

EC 2.4.99.25 · RXN-22462 · not reversible

ADP-L-glycero-beta-D-manno-heptose alpha-Hep-(1->3)-4-O-phospho-alpha-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli)
→
(heptosyl)3-Kdo2-lipid A-phosphate (E. coli) ADP H+
VK055_3501

RXN-22497

EC 4.3.2.2 · RXN-22497 · not reversible

producing
2-amino-2'-deoxy-N6-[(2S)-succino]adenylate
→
dZMP fumarate
VK055_1323

RXN-22498

EC 2.7.4.8 · RXN-22498 · not reversible

consuming
dZMP ATP
→
dZDP ADP
VK055_3472

RXN-22585

EC 4.2.1.178 · RXN-22585 · not reversible

difructose anhydride III H2O
→
inulobiose
No mapped protein

RXN-22591

EC 3.2.1.52 · RXN-22591 · not reversible

a peptidoglycan H2O
→
a peptidoglycan with N-acetyl-beta-D-glucosamine at the reducing end a peptidoglycan with N-acetylmuramoyl-pentapeptide at the non-reducing end
VK055_1361

RXN-22603

EC - · RXN-22603 · reversible

(R)-lactic acid
⇌
(S)-lactic acid
No mapped protein

RXN-22604

EC - · RXN-22604 · reversible

(R)-lactate H+
⇌
(R)-lactic acid
No mapped protein

RXN-22605

EC - · RXN-22605 · not reversible

(S)-lactate H+
→
(S)-lactic acid
No mapped protein

RXN-22606

EC - · RXN-22606 · not reversible

L-cysteine fumarate
→
S-(2-succinyl)-L-cysteine
No mapped protein

RXN-22607

EC - · RXN-22607 · reversible

lactate H+
⇌
lactic acid
No mapped protein

RXN-22608

EC 6.3.2.10 · RXN-22608 · not reversible

producing
D-alanyl-D-lactate UDP-MurNAc-L-Ala-gamma-D-Glu-meso-DAP ATP
→
UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-lactate ADP H+ phosphate
VK055_2482

RXN-22610

EC 2.7.8.13 · RXN-22610 · not reversible

both
UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-lactate di-trans,octa-cis-undecaprenyl phosphate
→
Und-PP-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Lac UMP
VK055_2481

RXN-22611

EC 2.4.1.227 · RXN-22611 · not reversible

consuming
UDP-N-acetyl-alpha-D-glucosamine Und-PP-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Lac
→
Und-PP-[beta-D-GlcNAc-(1->4)]-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Lac H+ UDP
VK055_2477

RXN-22612

EC 3.2.1.52 · RXN-22612 · not reversible

a peptidoglycan (L. plantarum) H2O
→
a peptidoglycan with N-acetyl-beta-D-glucosamine at the reducing end (L. plantarum) a peptidoglycan with N-acetylmuramoyl-pentadepsipeptide at the non-reducing end (L. plantarum)
VK055_1361

RXN-22618

EC - · RXN-22618 · not reversible

a [1-Cys-peroxiredoxin]-L-cysteine hydrogen peroxide
→
a [1-Cys-peroxiredoxin]-S-hydroxy-L-cysteine H2O
VK055_1883

RXN-22623

EC 1.1.1.90 · RXN-22623 · reversible

benzyl alcohol NADP+
⇌
benzaldehyde H+ NADPH
VK055_0533

RXN-22643

EC - · RXN-22643 · not reversible

fumarate glutathione
→
S-(2-succinyl)-glutathione
No mapped protein

RXN-22697

EC - · RXN-22697 · not reversible

a [molybdopterin synthase sulfurtransferase]-L-cysteine an [L-cysteine desulfurase]-S-sulfanyl-L-cysteine
→
a [molybdopterin synthase sulfurtransferase]-S-sulfanyl-L-cysteine an [L-cysteine desulfurase]-L-cysteine
VK055_0323 VK055_4349 VK055_4350 VK055_4639

RXN-22698

EC 2.8.1.7 · RXN-22698 · not reversible

L-cysteine a [molybdopterin synthase sulfurtransferase]-L-cysteine
→
L-alanine a [molybdopterin synthase sulfurtransferase]-S-sulfanyl-L-cysteine
VK055_0323 VK055_4349 VK055_4350 VK055_4639

RXN-22699

EC 2.8.1.- · RXN-22699 · not reversible

a [TusE sulfur carrier protein]-S-sulfanylcysteine a [tRNA-uridine 2-sulfurtransferase]-L-cysteine
→
a [TusE sulfur carrier protein]-L-cysteine a [tRNA-uridine 2-sulfurtransferase]-S-sulfanyl-L-cysteine
No mapped protein

RXN-22709

EC 1.5.1.3 · RXN-22709 · not reversible

folate H+ NADPH
→
7,8-dihydrofolate monoglutamate NADP+
VK055_2529

RXN-22710

EC - · RXN-22710 · not reversible

L-glutamine H2O
→
L-glutamate H+ ammonia
No mapped protein

RXN-22711

EC - · RXN-22711 · not reversible

producing
chorismate H+ ammonia
→
(2S)-2-amino-4-deoxy-chorismate H2O
VK055_1193

RXN-22713

EC - · RXN-22713 · not reversible

chorismate H+ ammonia
→
4-amino-4-deoxychorismate H2O
VK055_0122

RXN-22729

EC - · RXN-22729 · not reversible

(2S)-2-amino-4-deoxy-chorismate
→
anthranilate pyruvate H+
VK055_1193

RXN-22734

EC - · RXN-22734 · not reversible

L-aspartate ATP ammonia
→
L-asparagine AMP diphosphate
VK055_1836

RXN-22735

EC 6.3.4.16 · RXN-22735 · not reversible

hydrogen carbonate ATP ammonia
→
carbamoyl phosphate ADP H+ phosphate
VK055_2533 VK055_2534

RXN-22738

EC 5.3.1.4 · RXN-22738 · reversible

alpha-D-galactopyranose
⇌
D-tagatopyranose
VK055_2513

RXN-22774

EC - · RXN-22774 · not reversible

L-leucine aldehydo-D-glucose
→
N-(1-deoxy-D-fructos-1-yl)-L-leucine H2O
No mapped protein

RXN-22775

EC - · RXN-22775 · not reversible

L-valine aldehydo-D-glucose
→
N-(1-deoxy-D-fructos-1-yl)-L-valine H2O
No mapped protein

RXN-22776

EC - · RXN-22776 · not reversible

aldehydo-D-glucose glycine
→
N-(1-deoxy-D-fructopyranos-1-yl)glycine H2O
No mapped protein

RXN-22777

EC - · RXN-22777 · not reversible

L-lysine aldehydo-D-glucose
→
N1-(1-deoxy-D-fructos-1-yl)-L-lysine H2O
No mapped protein

RXN-22778

EC - · RXN-22778 · not reversible

L-alanine aldehydo-D-glucose
→
N-(1-deoxy-D-fructos-1-yl)-L-alanine H2O
No mapped protein

RXN-22790

EC - · RXN-22790 · not reversible

L-glutamine aldehydo-D-glucose
→
N-(1-deoxy-D-fructos-1-yl)-L-glutamine H2O
No mapped protein

RXN-22914

EC - · RXN-22914 · not reversible

(R)-4'-phosphopantothenate CTP H+
→
(R)-4'-phosphopantothenoyl-cytidylate diphosphate
No mapped protein

RXN-22915

EC - · RXN-22915 · not reversible

(R)-4'-phosphopantothenoyl-cytidylate L-cysteine
→
(R)-4'-phosphopantothenoyl-L-cysteine CMP H+
No mapped protein

RXN-22975

EC 1.3.8.- · RXN-22975 · not reversible

(2E)-5-carboxy-2-pentenoyl-CoA FADH2
→
adipoyl-CoA FAD H+
No mapped protein

RXN-22997

EC 1.3.8.7 · RXN-22997 · reversible

adipoyl-CoA an oxidized electron-transfer flavoprotein H+
⇌
(2E)-5-carboxy-2-pentenoyl-CoA a reduced electron-transfer flavoprotein
No mapped protein

RXN-23219

EC 2.4.1.182 · RXN-23219 · not reversible

UDP-2-N-[(3R)-3-hydroxytetradecanoyl]-3-O-[(3R)-3-hydroxydodecanoyl]-alpha-D-glucosamine lipid X (Vibrio cholerae serogroup O1 El Tor)
→
lipid A disaccharide (Vibrio cholerae serogroup O1 El Tor) H+ UDP
VK055_2370

RXN-23220

EC 3.6.1.54 · RXN-23220 · not reversible

producing
UDP-2-N-[(3R)-3-hydroxytetradecanoyl]-3-O-[(3R)-3-hydroxydodecanoyl]-alpha-D-glucosamine H2O
→
lipid X (Vibrio cholerae serogroup O1 El Tor) H+ UMP
VK055_2067

RXN-23276

EC - · RXN-23276 · not reversible

nitric oxide superoxide
→
peroxynitrite
No mapped protein

RXN-23528

EC - · RXN-23528 · not reversible

L-asparagine aldehydo-D-glucose
→
N-(1-deoxy-D-fructos-1-yl)-L-asparagine H2O
No mapped protein

RXN-23888

EC - · RXN-23888 · not reversible

producing
L-histidine ATP H+
→
(L-histidyl)adenylate diphosphate
VK055_4656

RXN-23889

EC - · RXN-23889 · not reversible

L-isoleucine ATP H+
→
(L-isoleucyl)adenylate diphosphate
VK055_2554

RXN-23890

EC - · RXN-23890 · not reversible

L-leucine ATP H+
→
(L-leucyl)adenylate diphosphate
VK055_1858

RXN-23891

EC - · RXN-23891 · not reversible

producing
L-methionine ATP H+
→
(L-methionyl)adenylate diphosphate
VK055_4963

RXN-23894

EC - · RXN-23894 · not reversible

producing
L-glutamine ATP H+
→
(L-glutaminyl)adenylate diphosphate
VK055_1830

RXN-23929

EC - · RXN-23929 · not reversible

D-aspartate ATP H+
→
(D-aspartyl)adenylate diphosphate
VK055_0067

RXN-23934

EC - · RXN-23934 · not reversible

D-tyrosine ATP H+
→
(D-tyrosyl)adenylate diphosphate
VK055_0502

RXN-23949

EC - · RXN-23949 · not reversible

producing
L-norvaline ATP H+
→
(L-norvalyl)adenylate diphosphate
VK055_1858

RXN-23965

EC 2.7.1.50 · RXN-23965 · not reversible

5-(2-hydroxyethyl)-4-methyl-1,3-thiazole-2-carboxylate ATP
→
2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate ADP H+
VK055_4975

RXN-24006

EC 1.8.4.16 · RXN-24006 · not reversible

a [protein]-disulfide a reduced thioredoxin
→
a [protein]-dithiol an oxidized thioredoxin
No mapped protein

RXN-24036

EC - · RXN-24036 · not reversible

(octanoyl)adenylate a [lipoyl-carrier protein]-L-lysine
→
a [lipoyl-carrier protein] N6-octanoyl-L-lysine AMP H+
VK055_2590 VK055_5062

RXN-24043

EC 1.17.7.4 · RXN-24043 · not reversible

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate a reduced flavodoxin
→
an oxidized flavodoxin prenyl diphosphate H2O
VK055_2551

RXN-24044

EC 1.17.7.4 · RXN-24044 · not reversible

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate a reduced flavodoxin
→
an oxidized flavodoxin isopentenyl diphosphate H2O
VK055_2551

RXN-24046

EC - · RXN-24046 · not reversible

(1R,2S,5S,6S)-2-succinyl-5-enolpyruvyl-6-hydroxycyclohex-3-ene-1-carboxylate
→
(1R,5S,6S)-2-succinyl-5-enolpyruvyl-6-hydroxycyclohex-2-ene-1-carboxylate
No mapped protein

RXN-24090

EC - · RXN-24090 · not reversible

a 5-carboxymethylaminomethyl-2-thiouridine34 in tRNA geranyl diphosphate
→
a 5-carboxymethylaminomethyl-2-(S-geranyl)thiouridine34 in tRNA diphosphate
VK055_2071

RXN-24091

EC - · RXN-24091 · not reversible

a 5-carboxymethylaminomethyl-2-(S-geranyl)thiouridine34 in tRNA selenophosphate
→
(2E)-3,7-dimethylocta-2,6-diene-1-thiol a 5-carboxymethylaminomethyl-2-(Se-phospho)selenouridine34 in tRNA
VK055_2071

RXN-24092

EC - · RXN-24092 · not reversible

a 5-carboxymethylaminomethyl-2-(Se-phospho)selenouridine34 in tRNA H2O
→
a 5-carboxymethylaminomethyl-2-selenouridine34 in tRNA phosphate
VK055_2071

RXN-24129

EC - · RXN-24129 · not reversible

glutathione methylglyoxal
→
S-lactoylglutathione hemithioacetal
No mapped protein

RXN-24481

EC 1.1.1.27 · RXN-24481 · reversible

(S)-3-(phenyl)lactate NAD+
⇌
3-phenyl-2-oxopropanoate H+ NADH
VK055_0858

RXN-24553

EC - · RXN-24553 · reversible

a reduced two electron carrier cysteinopantetheine
⇌
L-cysteine an oxidized electron carrier pantetheine
No mapped protein

RXN-24769

EC - · RXN-24769 · not reversible

a [protein] S-acetyl-L-cysteine an acyl-CoA
→
a 3-oxoacyl-CoA a [protein]-L-cysteine
VK055_4877

RXN-24786

EC - · RXN-24786 · not reversible

4-aminobutanoate CO2
→
4-(carboxyamino)butanoate H+
No mapped protein

RXN-25009

EC - · RXN-25009 · not reversible

a [4Fe-4S] iron-sulfur cluster linked by 3 L-cysteine residues an [L-cysteine desulfurase]-S-sulfanyl-L-cysteine
→
a [4Fe-5S] iron-sulfur cluster linked by 3 L-cysteine residues an [L-cysteine desulfurase]-L-cysteine
VK055_0323 VK055_4349 VK055_4350 VK055_4639

RXN-25010

EC 2.8.1.7 · RXN-25010 · not reversible

L-cysteine a [4Fe-4S] iron-sulfur cluster linked by 3 L-cysteine residues
→
L-alanine a [4Fe-5S] iron-sulfur cluster linked by 3 L-cysteine residues
VK055_0323 VK055_4349 VK055_4350 VK055_4639

RXN-25163

EC 6.3.1.20 · RXN-25163 · not reversible

an [LbpA protein]-L-lysine octanoate ATP
→
an [LbpA protein] N6-octanoyl-L-lysine AMP H+ diphosphate
VK055_2590 VK055_5062

RXN-25164

EC - · RXN-25164 · not reversible

(octanoyl)adenylate an [LbpA protein]-L-lysine
→
an [LbpA protein] N6-octanoyl-L-lysine AMP H+
VK055_2590 VK055_5062

RXN-25212

EC 2.3.1.5 · RXN-25212 · not reversible

4-aminosalicylate acetyl-CoA
→
N-acetyl-4-aminosalicylate coenzyme A
VK055_0599

RXN-25217

EC 2.4.2.3 · RXN-25217 · not reversible

capecitabine phosphate
→
2-deoxy-alpha-D-ribose 1-phosphate deglycocapecitabine
VK055_3149

RXN-25225

EC 2.4.2.2 · RXN-25225 · not reversible

doxifluridine phosphate
→
2-deoxy-alpha-D-ribose 1-phosphate 5-fluorouracil
VK055_2593 VK055_3149

RXN-25236

EC 3.5.4.5 · RXN-25236 · not reversible

gemcitabine H+ H2O
→
2', 2'-difluorodeoxyuridine ammonium
VK055_4939

RXN-25247

EC 2.4.2.2 · RXN-25247 · not reversible

trifluridine phosphate
→
2-deoxy-alpha-D-ribose 1-phosphate trifluorothymine
VK055_2593 VK055_3149

RXN-25248

EC 2.3.1.5 · RXN-25248 · not reversible

acetyl-CoA isoniazid
→
N'-acetylisoniazid coenzyme A
VK055_0599

RXN-25249

EC 2.3.1.5 · RXN-25249 · not reversible

acetyl-CoA hydralazine
→
N'-acetylhydralazine coenzyme A
VK055_0599

RXN-25310

EC - · RXN-25310 · not reversible

S-adenosyl-L-methionine a reduced flavodoxin a sulfurated [sulfur carrier] dethiobiotin
→
4,5-secobiotin 5'-deoxyadenosine L-methionine an oxidized flavodoxin an unsulfurated [sulfur carrier] H+
VK055_1731

RXN-25314

EC 2.4.2.21 · RXN-25314 · not reversible

5-hydroxybenzimidazole beta-nicotinate D-ribonucleotide
→
6-hydroxybenzimidazole ribotide phosphate nicotinate H+
VK055_4344 VK055_5057

RXN-25319

EC 2.7.8.26 · RXN-25319 · not reversible

consuming
5-hydroxybenzimidazole ribotide adenosylcobinamide-GDP
→
Coalpha-[alpha-(5-hydroxybenzimidazolyl)]-Cobeta-adenosylcobamide GMP H+
VK055_5056

RXN-25425

EC - · RXN-25425 · not reversible

5-aminopentanal
→
1-piperideine H+ H2O
No mapped protein

RXN-25427

EC - · RXN-25427 · reversible

1-piperideine H+
⇌
2-piperideine
No mapped protein

RXN-25428

EC - · RXN-25428 · not reversible

2-piperideine
→
(2R,3'R)-tetrahydroanabasine H+
No mapped protein

RXN-25434

EC - · RXN-25434 · not reversible

1-piperideine H+
→
(2R,3'R)-tetrahydroanabasine
No mapped protein

RXN-25448

EC - · RXN-25448 · not reversible

a 3-oxododecanoyl-[acp] malonyl-CoA H+
→
3,5-dioxotetradecanoyl-[acp] CO2 coenzyme A
No mapped protein

RXN-25449

EC 1.3.1.9 · RXN-25449 · reversible

5-oxotetradecanoyl-[acp] NAD+
⇌
(2E)-5-oxotetradec-2-enoyl-[acp] H+ NADH
No mapped protein

RXN-25450

EC 1.2.1.80 · RXN-25450 · not reversible

5-oxotetradecanoyl-[acp] H+ NADPH
→
5-oxotetradecanal a soluble [acyl-carrier protein] NADP+
No mapped protein

RXN-25451

EC 2.6.1.- · RXN-25451 · reversible

5-oxotetradecanal L-alanine
⇌
1-aminotetradecan-5-one pyruvate
No mapped protein

RXN-25452

EC - · RXN-25452 · not reversible

1-aminotetradecan-5-one
→
koreenceine B H2O
No mapped protein

RXN-25455

EC 1.1.1.100 · RXN-25455 · not reversible

both
3,5-dioxotetradecanoyl-[acp] H+ NADPH
→
3R-hydroxy-5-oxotetradecanoyl-[acp] NADP+
VK055_0788 VK055_1374

RXN-25456

EC 4.2.1.59 · RXN-25456 · not reversible

consuming
3R-hydroxy-5-oxotetradecanoyl-[acp]
→
(2E)-5-oxotetradec-2-enoyl-[acp] H2O
VK055_1504 VK055_2372

RXN-25472

EC 2.7.1.15 · RXN-25472 · not reversible

producing
alpha-D-ribofuranose ATP
→
alpha-D-ribose 5-phosphate ADP H+
VK055_3316

RXN-25627

EC 3.2.1.22 · RXN-25627 · not reversible

melibiose
→
D-glucopyranose manninotriose
VK055_3274

RXN-25628

EC 3.2.1.22 · RXN-25628 · not reversible

consuming
manninotriose melibiose
→
D-glucopyranose verbascotetraose
VK055_3274

RXN-25629

EC 3.2.1.22 · RXN-25629 · not reversible

lactulose melibiose
→
D-glucopyranose alpha-D-Gal-(1->6)-beta-D-Gal-(1->4)-D-Fruf
VK055_3274

RXN-25638

EC - · RXN-25638 · not reversible

Mn2+ superoxide H+
→
Mn3+ hydrogen peroxide
No mapped protein

RXN-25639

EC - · RXN-25639 · not reversible

Mn3+ superoxide
→
Mn2+ dioxygen
No mapped protein

RXN-2881

EC - · R09093 · RXN-2881 · not reversible

a tetrahydrofolate formaldehyde
→
a 5,10-methylenetetrahydrofolate H2O
No mapped protein

RXN2B4Q-51

EC 3.6.1.54 · RXN2B4Q-51 · not reversible

UDP-2-N-[(3R)-3-hydroxydodecanoyl]-3-N-[(3R)-3-hydroxyhexanoyl]-alpha-3-amino-3-deoxy-D-glucosamine H2O
→
lipid X (Brucella) H+ UMP
VK055_2067

RXN2B4Q-52

EC 2.4.1.182 · RXN2B4Q-52 · not reversible

UDP-2-N-[(3R)-3-hydroxydodecanoyl]-3-N-[(3R)-3-hydroxyhexanoyl]-alpha-3-amino-3-deoxy-D-glucosamine lipid X (Brucella)
→
dephospho-lipid IVA (Brucella) H+ UDP
VK055_2370

RXN2B4Q-53

EC 2.7.1.130 · RXN2B4Q-53 · not reversible

dephospho-lipid IVA (Brucella) ATP
→
lipid IVA (Brucella) ADP H+
VK055_1542

RXN2DDB-4

EC 1.3.1.- · RXN2DDB-4 · not reversible

4-vinylcatechol H+ NADH
→
4-ethylcatechol NAD+
No mapped protein

RXN2DNV-1

EC 3.6.1.54 · RXN2DNV-1 · not reversible

UDP-2-N-[(3R)-3-hydroxyoctadecanoyl]-3-O-[(3R)-3-hydroxyhexadecanoyl]-alpha-D-glucosamine H2O
→
lipid X (H. pylori) H+ UMP
VK055_2067

RXN2DNV-2

EC 2.4.1.182 · RXN2DNV-2 · not reversible

UDP-2-N-[(3R)-3-hydroxyoctadecanoyl]-3-O-[(3R)-3-hydroxyhexadecanoyl]-alpha-D-glucosamine lipid X (H. pylori)
→
lipid A disaccharide (H. pylori) H+ UDP
VK055_2370

RXN2DNV-3

EC 2.7.1.130 · RXN2DNV-3 · not reversible

lipid A disaccharide (H. pylori) ATP
→
lipid IVA (H. pylori) ADP H+
VK055_1542

RXN2DNV-4

EC 2.4.99.12 · RXN2DNV-4 · not reversible

CMP-3-deoxy-beta-D-manno-octulosonate lipid IVA (H. pylori)
→
alpha-Kdo-(2->6)-lipid IVA (H. pylori) CMP H+
VK055_3497

RXN2DNV-5

EC 2.4.99.13 · RXN2DNV-5 · not reversible

CMP-3-deoxy-beta-D-manno-octulosonate alpha-Kdo-(2->6)-lipid IVA (H. pylori)
→
alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (H. pylori) CMP H+
VK055_3497

RXN2G6Z-1

EC 2.7.1.130 · RXN2G6Z-1 · not reversible

lipid A disaccharide (Vibrio cholerae serogroup O1 El Tor) ATP
→
lipid IVA (Vibrio cholerae serogroup O1 El Tor) ADP H+
VK055_1542

RXN2PN3-45

EC - · RXN2PN3-45 · not reversible

consuming
S-lactoylglutathione hemithioacetal
→
(R)-S-lactoylglutathione
VK055_0487

RXN-3482

EC - · RXN-3482 · not reversible

hydroxylamine pyruvate
→
pyruvic oxime H2O
No mapped protein

RXN3O-12

EC 1.14.13.- · RXN3O-12 · not reversible

2-methoxy-6-(all-trans-hexaprenyl)phenol H+ NADPH dioxygen
→
2-methoxy-6-(all trans-hexaprenyl)benzene-1,4-diol H2O NADP+
VK055_4140

RXN-6081

EC - · RXN-6081 · not reversible

(S)-2-acetolactate an oxidized electron carrier H+
→
a reduced two electron carrier diacetyl CO2
No mapped protein

RXN-6268

EC - · RXN-6268 · reversible

betaine aldehyde hydrate
⇌
betaine aldehyde H2O
No mapped protein

RXN-6423

EC - · R07408 · RXN-6423 · reversible

4-aminobutanal
⇌
1-pyrroline H2O
No mapped protein

RXN-6424

EC - · RXN-6424 · not reversible

N-(3-aminopropyl)-4-aminobutanal
→
1-(3-aminopropyl)-pyrrolinium H2O
No mapped protein

RXN-6425

EC - · RXN-6425 · not reversible

1-(3-aminopropyl)-pyrrolinium
→
1,5-diazabicyclononane H+
No mapped protein

RXN-7101

EC - · RXN-7101 · not reversible

a [biotin carboxyl-carrier protein]-N6-biotinyl-L-lysine
→
a [biotin carboxyl-carrier-protein dimer]-N6-biotinyl-L-lysine
No mapped protein

RXN-7282

EC 5.3.2.- · RXN-7282 · reversible

2-oxopent-4-enoate
⇌
(2Z)-2-hydroxypenta-2,4-dienoate
No mapped protein

RXN-7561

EC 2.3.1.109 · RXN-7561 · not reversible

L-ornithine succinyl-CoA
→
N2-succinyl-L-ornithine H+ coenzyme A
VK055_1015 VK055_1236

RXN-7566

EC 1.21.4.2 · R07226 · RXN-7566 · not reversible

a reduced thioredoxin glycine H+ phosphate
→
acetyl phosphate an oxidized thioredoxin H2O ammonium
No mapped protein

RXN-7592

EC - · RXN-7592 · not reversible

formyl-L-isoglutamine H2O
→
L-isoglutamine formate
No mapped protein

RXN-7593

EC - · RXN-7593 · not reversible

4-imidazolone-5-propanoate a reduced two electron carrier H2O dioxygen
→
4-oxoglutaramate an oxidized electron carrier formate ammonium
No mapped protein

RXN-761

EC 2.4.1.347 · RXN-761 · not reversible

ADP-alpha-D-glucose D-glucopyranose 6-phosphate
→
alpha,alpha-trehalose 6-phosphate ADP H+
VK055_0055

RXN-7657

EC 1.1.1.1 · RXN-7657 · reversible

isobutanol NAD+
⇌
isobutanal H+ NADH
VK055_0526

RXN-7694

EC 1.1.1.1 · RXN-7694 · reversible

2-methylbutanol NAD+
⇌
2-methylbutanal H+ NADH
VK055_0526

RXN-7706

EC 1.1.1.1 · RXN-7706 · reversible

methionol NAD+
⇌
3-(methylsulfanyl)propanal H+ NADH
VK055_0526

RXN-7708

EC 2.6.1.28 · RXN-7708 · reversible

3-phenyl-2-oxopropanoate L-methionine
⇌
4-(methylsulfanyl)-2-oxobutanoate L-phenylalanine
VK055_1888

RXN-7716

EC 1.8.1.4 · RXN-7716 · not reversible

a [2-oxoglutarate dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine NAD+
→
a [2-oxoglutarate dehydrogenase E2 protein] N6-lipoyl-L-lysine H+ NADH
VK055_2296 VK055_2450

RXN-7719

EC 1.8.1.4 · RXN-7719 · reversible

an [apo BCAA dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine NAD+
⇌
a [BCAA dehydrogenase E2 protein] N6-lipoyl-L-lysine H+ NADH
VK055_2296 VK055_2450

RXN-7919

EC 3.1.2.6 · R04090 · RXN-7919 · not reversible

S-(2-hydroxyacyl)glutathione H2O
→
a 2-hydroxy carboxylate glutathione H+
VK055_2339

RXN-7931

EC 5.3.3.8 · R04100 · RXN-7931 · reversible

(3Z)-dodec-3-enoyl-CoA
⇌
(2E)-dodec-2-enoyl-CoA
No mapped protein

RXN-8182

EC 1.2.1.20 · R10982 · RXN-8182 · not reversible

glutarate semialdehyde H2O NADP+
→
glutarate H+ NADPH
No mapped protein

RXN-8315

EC - · RXN-8315 · reversible

sulfite H+
⇌
hydrogensulfite
No mapped protein

RXN-8342

EC 2.8.1.12 · RXN-8342 · not reversible

both
a thiocarboxylated [molybdopterin-synthase sulfur-carrier protein subunit] cyclic pyranopterin phosphate H2O
→
a molybdopterin synthase sulfur carrier subunit molybdopterin H+
VK055_1717

RXN-8505

EC 1.14.14.9 · RXN-8505 · not reversible

producing
(4-hydroxyphenyl)acetate FADH2 dioxygen
→
(3,4-dihydroxyphenyl)acetate FAD H+ H2O
VK055_2659 VK055_2660

RXN-8629

EC 1.8.1.4 · RXN-8629 · reversible

a [glycine-cleavage complex H protein] N6-dihydrolipoyl-L-lysine NAD+
⇌
a [glycine-cleavage complex H protein] N6-[(R)-lipoyl]-L-lysine H+ NADH
VK055_2296 VK055_2450 VK055_4143

RXN-8655

EC - · R07771 · RXN-8655 · not reversible

[(R)-lipoyl]adenylate a [lipoyl-carrier protein]-L-lysine
→
a [lipoyl-carrier protein]-N6-[(R)-lipoyl]-L-lysine AMP H+
VK055_2590 VK055_5062

RXN-8899

EC - · R08698 · RXN-8899 · not reversible

2-aminoprop-2-enoate H2O
→
pyruvate ammonium
No mapped protein

RXN8J2-155

EC 3.5.1.28 · RXN8J2-155 · not reversible

Und-PP-[beta-D-GlcNAc-(1->4)]-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Ala H2O
→
L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramate
VK055_1266 VK055_2459 VK055_4300 VK055_4733

RXN8J2-192

EC - · RXN8J2-192 · not reversible

a [tRNA-uridine 2-sulfurtransferase]-L-cysteine an [L-cysteine desulfurase]-S-sulfanyl-L-cysteine
→
a [tRNA-uridine 2-sulfurtransferase]-S-sulfanyl-L-cysteine an [L-cysteine desulfurase]-L-cysteine
VK055_0323 VK055_4349 VK055_4350 VK055_4639

RXN-9003

EC 2.5.1.39 · R05616 · RXN-9003 · not reversible

4-hydroxybenzoate all-trans-hexaprenyl diphosphate
→
4-hydroxy-3-(all-trans-hexaprenyl)benzoate diphosphate
VK055_3045

RXN-9101

EC 2.7.7.66 · RXN-9101 · not reversible

2'-(5''-triphospho-alpha-D-ribosyl)-3'-dephospho-CoA [an apo malonate decarboxylase acyl-carrier protein]
→
[a holo malonate decarboxylase acyl-carrier-protein] diphosphate
VK055_0945

RXN-9222

EC 2.5.1.39 · RXN-9222 · not reversible

4-hydroxybenzoate all-trans-heptaprenyl diphosphate
→
4-hydroxy-3-(all-trans-heptaprenyl)benzoate diphosphate
VK055_3045

RXN-9223

EC 4.1.1.98 · RXN-9223 · reversible

4-hydroxy-3-(all-trans-heptaprenyl)benzoate H+
⇌
2-(all-trans-heptaprenyl)phenol CO2
VK055_3138

RXN-9224

EC 1.14.13.240 · RXN-9224 · not reversible

2-(all-trans-heptaprenyl)phenol H+ NADPH dioxygen
→
3-(all-trans-heptaprenyl)benzene-1,2-diol H2O NADP+
VK055_3145

RXN-9226

EC 1.14.13.- · RXN-9226 · not reversible

2-methoxy-6-(all-trans-heptaprenyl)phenol H+ NADPH dioxygen
→
2-methoxy-6-(all trans-heptaprenyl)benzene-1,4-diol H2O NADP+
VK055_4140

RXN-9229

EC 2.1.1.64 · RXN-9229 · not reversible

3-demethylubiquinol-7 S-adenosyl-L-methionine
→
S-adenosyl-L-homocysteine ubiquinol-7 H+
VK055_4874

RXN-9230

EC 2.5.1.39 · RXN-9230 · not reversible

4-hydroxybenzoate all-trans-decaprenyl diphosphate
→
4-hydroxy-3-(all-trans-decaprenyl)benzoate diphosphate
VK055_3045

RXN-9231

EC 4.1.1.98 · RXN-9231 · reversible

4-hydroxy-3-(all-trans-decaprenyl)benzoate H+
⇌
2-(all-trans-decaprenyl)phenol CO2
VK055_3138

RXN-9232

EC 1.14.13.240 · RXN-9232 · not reversible

2-(all-trans-decaprenyl)phenol H+ NADPH dioxygen
→
3-(all-trans-decaprenyl)benzene-1,2-diol H2O NADP+
VK055_3145

RXN-9234

EC 1.14.13.- · RXN-9234 · not reversible

2-methoxy-6-(all-trans-decaprenyl)phenol H+ NADPH dioxygen
→
2-methoxy-6-(all-trans-decaprenyl)benzene-1,4-diol H2O NADP+
VK055_4140

RXN-9237

EC 2.1.1.64 · RXN-9237 · not reversible

3-demethylubiquinol-10 S-adenosyl-L-methionine
→
S-adenosyl-L-homocysteine ubiquinol-10 H+
VK055_4874

RXN-9238

EC 4.1.1.98 · RXN-9238 · reversible

4-hydroxy-3-(all-trans-nonaprenyl)benzoate H+
⇌
2-(all-trans-nonaprenyl)phenol CO2
VK055_3138

RXN-9239

EC 1.14.13.240 · RXN-9239 · not reversible

2-(all-trans-nonaprenyl)phenol H+ NADPH dioxygen
→
3-(all-trans-nonaprenyl)benzene-1,2-diol H2O NADP+
VK055_3145

RXN-9241

EC 1.14.13.- · RXN-9241 · not reversible

2-methoxy-6-(all-trans-nonaprenyl)phenol H+ NADPH dioxygen
→
2-methoxy-6-(all trans-nonaprenyl)benzene-1,4-diol H2O NADP+
VK055_4140

RXN-9376

EC - · RXN-9376 · reversible

glycine ATP
⇌
(glycyl)adenylate diphosphate
VK055_4487

RXN-9559

EC - · RXN-9559 · not reversible

formaldehyde norfuraneol
→
4-hydroxy-5-methyl-2-methylene-3(2H)-furanone H2O
No mapped protein

RXN-9560

EC - · RXN-9560 · not reversible

acetaldehyde norfuraneol
→
(2E)-2-ethylidene-4-hydroxy-5-methyl-3(2H)-furanone H2O
No mapped protein

RXN-9561

EC - · RXN-9561 · not reversible

1-propanal norfuraneol
→
(2E)-4-hydroxy-5-methyl-2-propylidene-3(2H)-furanone H2O
No mapped protein

RXN-9562

EC - · RXN-9562 · not reversible

1-butanal norfuraneol
→
(2E)-2-butylidene-4-hydroxy-5-methyl-3(2H)-furanone H2O
No mapped protein

RXN-9590

EC 2.3.1.274 · RXN-9590 · reversible

a fatty acyl-[acyl-carrier protein] phosphate
⇌
a soluble [acyl-carrier protein] an acyl phosphate
No mapped protein

RXN-9591

EC 2.3.1.275 · RXN-9591 · not reversible

an acyl phosphate sn-glycerol 3-phosphate
→
a 2-lysophosphatidate phosphate
VK055_4009

RXN-9644

EC 6.2.1.3 · RXN-9644 · not reversible

oleate ATP coenzyme A
→
oleoyl-CoA AMP diphosphate
No mapped protein

RXN-9652

EC 2.3.1.41 · RXN-9652 · not reversible

producing
a decanoyl-[acp] malonyl-CoA H+
→
a 3-oxododecanoyl-[acp] CO2 coenzyme A
VK055_4800

RXN-9758

EC 1.2.1.8 · RXN-9758 · not reversible

dimethyl(3-oxopropyl)sulfanium H2O NAD+
→
dimethylsulfoniopropanoate H+ NADH
VK055_1952

RXN-9771

EC - · RXN-9771 · not reversible

2-iminosuccinate H+ H2O
→
oxaloacetate ammonium
No mapped protein

RXN-9772

EC 1.5.98.- · RXN-9772 · not reversible

L-aspartate fumarate
→
2-iminosuccinate succinate H+
VK055_4601

RXN-9788

EC 2.8.1.- · RXN-9788 · not reversible

a [ThiI sulfur-carrier protein]-S-sulfanyl-L-cysteine a carboxy-adenylated-[ThiS sulfur-carrier protein] a reduced ferredoxin [iron-sulfur] cluster
→
a [ThiI sulfur-carrier protein]-L-cysteine a thiocarboxylated-[ThiS sulfur-carrier protein] an oxidized ferredoxin [iron-sulfur] cluster AMP
No mapped protein

RXN-982

EC 1.20.4.1 · R05747 · RXN-982 · not reversible

a reduced glutaredoxin arsenate glutathione H+
→
a [glutaredoxin]-glutathione disulfide arsenous acid H2O
VK055_4217 VK055_4693

RXN-9836

EC 1.3.1.- · RXN-9836 · not reversible

4-vinylguaiacol H+ NADH
→
4-ethylguaiacol NAD+
No mapped protein

RXN-9837

EC 1.3.1.- · RXN-9837 · not reversible

4-vinylphenol H+ NADH
→
4-ethylphenol NAD+
No mapped protein

RXN-9871

EC 1.14.12.- · RXN-9871 · not reversible

3-chlorobenzoate H+ NADH dioxygen
→
3-chloro-3,5-cyclohexadiene-l,2-diol-1-carboxylate NAD+
VK055_0612 VK055_0613

RXN-9872

EC 1.14.12.- · RXN-9872 · not reversible

3-chlorobenzoate H+ NADH dioxygen
→
5-chloro-3,5-cyclohexadiene-l,2-diol-1-carboxylate NAD+
VK055_0612 VK055_0613

RXN-9873

EC 1.3.1.- · RXN-9873 · not reversible

3-chloro-3,5-cyclohexadiene-l,2-diol-1-carboxylate NAD+
→
3-chlorocatechol CO2 NADH
No mapped protein

RXN-9874

EC 1.3.1.- · RXN-9874 · not reversible

5-chloro-3,5-cyclohexadiene-l,2-diol-1-carboxylate NAD+
→
4-chlorocatechol CO2 NADH
No mapped protein

RXN-9909

EC 1.1.1.90 · RXN-9909 · reversible

3-chlorobenzyl alcohol NAD+
⇌
3-chlorobenzaldehyde H+ NADH
VK055_0533

RXN-9985

EC 3.2.1.26 · RXN-9985 · not reversible

a beta-D-fructofuranoside H2O
→
an alcohol beta-D-fructofuranose
VK055_2036 VK055_4263

TRANS-RXN0-286

EC 7.5.99.- · TRANS-RXN0-286 · not reversible

Und-PP-[beta-D-GlcNAc-(1->4)]-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Ala H+
→
Und-PP-[beta-D-GlcNAc-(1->4)]-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Ala H+
No mapped protein

TREHALOSE6PSYN-RXN

EC 2.4.1.15 · R00836 · TREHALOSE6PSYN-RXN · not reversible

D-glucopyranose 6-phosphate UDP-alpha-D-glucose
→
alpha,alpha-trehalose 6-phosphate H+ UDP
VK055_0055

UDPMANACATRANS-RXN

EC 2.4.1.180 · R04477 · UDPMANACATRANS-RXN · not reversible

UDP-N-acetyl-alpha-D-mannosaminuronate alpha-D-GlcNAc-PP-Und
→
beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-PP-Und H+ UDP
No mapped protein