Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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Applied filters EC Number: 2.5.1.3

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EC Number: 2.5.1.3 ×
# Protein Description Gene Structure EC GO Metabolism Druggability (P2Rank) P2RANK ligandability score for the best pocket in the experimental structure (0–1). Higher values indicate higher predicted ligandability. Available only for genomes analyzed with the curated pipeline. Druggability (FPocket) FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
1 KP13_00377 4-hydroxybenzoate octaprenyltransferase ubiA AlphaFold DB model + ColabFold model
2.5.1.39
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0004659Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor). GO:0016765Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor). +36 total
No map 0.989 0.994 Hit 39.6% 2.58e-25
2 KP13_01805 Undecaprenyl pyrophosphate synthase uppS AlphaFold DB model + ColabFold model
2.5.1.31
GO:0016765Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor). GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0008834Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 8 isopentenyl diphosphate = di-trans,octa-cis-undecaprenyl diphosphate + 8 diphosphate. +58 total
No map 0.958 0.863 Hit 42.9% 3.12e-10
3 KP13_31609 Thiamine-phosphate synthase thiE AlphaFold DB model + ColabFold model
2.5.1.3
GO:0009228The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver. GO:0004789Catalysis of the reaction: 4-amino-2-methyl-5-diphosphomethylpyrimidine + 4-methyl-5-(2-phosphoethyl)-thiazole + H+ = diphosphate + thiamine phosphate. GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. +25 total
No map 0.943 0.713 No Hit 0.0% —
Page 1 of 1 · 3 total proteins