Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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6 proteins

Scoring formula None

Sorted by Druggability (descending)

Applied filters EC Number: 3.6.1.1

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EC Number: 3.6.1.1 ×
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
1 KP13_02795 ADP-ribose pyrophosphatase nudF Experimental + ColabFold
3.6.1.13
GO:0016818Catalysis of the hydrolysis of any acid anhydride which contains phosphorus. GO:0046872Binding to a metal ion. GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. +69 total
0.75 No Hit 0.0% —
2 KP13_04544 Inorganic pyrophosphatase AlphaFold + ColabFold
3.6.1.1
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0006796The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid. GO:0000287Binding to a magnesium (Mg) ion. +14 total
0.633 Hit 35.3% 5.61e-10
3 KP13_00972 Nucleoside triphosphatase nudI nudI Experimental + ColabFold
3.6.1.9 3.6.1.12 3.6.1.- +14 total
GO:0016818Catalysis of the hydrolysis of any acid anhydride which contains phosphorus. GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. GO:0047840Catalysis of the reaction: dCTP + H2O = dCMP + H+ + diphosphate. +25 total
0.472 No Hit 0.0% —
4 KP13_02518 Multifunctional protein surE surE AlphaFold + ColabFold
3.1.3.5 3.1.3.6 3.6.1.11
GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. GO:0008252Catalysis of the reaction: a nucleotide + H2O = a nucleoside + phosphate. GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. +58 total
0.338 No Hit 0.0% —
5 KP13_01250 Inorganic pyrophosphatase ppa AlphaFold + ColabFold
3.6.1.1
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0006796The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid. GO:0000287Binding to a magnesium (Mg) ion. +14 total
0.328 No Hit 0.0% —
6 KP13_00933 Exopolyphosphatase ppx Experimental + ColabFold
3.6.1.11
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0004309Catalysis of the reaction: polyphosphate(n) + H2O = polyphosphate(n-1) + phosphate. GO:0046872Binding to a metal ion. +14 total
0.317 No Hit 0.0% —
Page 1 of 1 · 6 total proteins