Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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Applied filters EC Number: 7.2.4.2

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EC Number: 7.2.4.2 ×
# Protein Description Gene Structure EC GO Metabolism Druggability (P2Rank) P2RANK ligandability score for the best pocket in the experimental structure (0–1). Higher values indicate higher predicted ligandability. Available only for genomes analyzed with the curated pipeline. Druggability (FPocket) FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
1 KP13_03250 Oxaloacetate decarboxylase alpha chain Experimental + AlphaFold DB model + ColabFold model
7.2.4.2
GO:0008948Catalysis of the reaction: H+ + oxaloacetate = CO2 + pyruvate. GO:0003824Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. GO:0006814The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. +47 total
No map 0.911 0.3 Hit 38.1% 3.66e-06
2 KP13_31779 Oxaloacetate decarboxylase beta chain AlphaFold DB model + ColabFold model
7.2.4.2
GO:0016829Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring. GO:0006814The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +14 total
No map 0.427 0.824 No Hit 0.0% —
3 KP13_02987 putative oxaloacetate decarboxylase gamma chain oadG AlphaFold DB model + ColabFold model
7.2.4.2
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0015081Enables the transfer of sodium ions (Na+) from one side of a membrane to the other. GO:0036376The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region. +36 total
No map N/A 0.317 No Hit 0.0% —
Page 1 of 1 · 3 total proteins