Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 / 5842 proteins

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Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
4701 KP13_05057 hypothetical protein ColabFold – – 0.643 No Hit 0.0% —
4702 KP13_05059 putative murein peptide carboxypeptidase AlphaFold + ColabFold –
GO:0004180Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain. GO:0008236Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). GO:0006508The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
0.447 No Hit 0.0% —
4703 KP13_05060 putative glycosyltransferase AlphaFold + ColabFold – – 0.51 No Hit 0.0% —
4704 KP13_05061 putative sensor histidine protein kinase AlphaFold + ColabFold –
GO:0016310The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. GO:0016772Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. +25 total
0.825 No Hit 0.0% —
4705 KP13_05062 Alkaline phosphatase synthesis transcriptional regulatory protein phoP AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0000160A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). +47 total
0.563 No Hit 0.0% —
4706 KP13_05063 hypothetical protein AlphaFold + ColabFold – – 0.547 No Hit 0.0% —
4707 KP13_05064 hypothetical protein ColabFold –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. +14 total
0.745 No Hit 0.0% —
4708 KP13_05067 insertion element IS1 protein insA AlphaFold + ColabFold –
GO:0006313A type of transposition in which a transposable element (transposon) is moved to another part of a genome, either by a cut-and-paste mechanism or a replicative mechanism.
0.438 No Hit 0.0% —
4709 KP13_05068 DsbA-like thioredoxin domain-containing protein AlphaFold + ColabFold –
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
0.836 No Hit 0.0% —
4710 KP13_05069 hypothetical protein AlphaFold + ColabFold – – 0.155 No Hit 0.0% —
4711 KP13_05070 hypothetical protein AlphaFold + ColabFold – – 0.959 No Hit 0.0% —
4712 KP13_05071 hypothetical protein AlphaFold + ColabFold – – 0.674 No Hit 0.0% —
4713 KP13_05072 hypothetical protein AlphaFold + ColabFold – – 0.117 No Hit 0.0% —
4714 KP13_05073 hypothetical protein AlphaFold + ColabFold – – 0.559 No Hit 0.0% —
4715 KP13_05074 hypothetical protein AlphaFold + ColabFold – – 0.196 No Hit 0.0% —
4716 KP13_05076 Multidrug efflux pump KexD kexD AlphaFold + ColabFold –
GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0015562Enables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane. GO:0042908The directed movement of a xenobiotic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A xenobiotic is a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. +58 total
0.911 No Hit 0.0% —
4717 KP13_05077 GNAT family acetyltransferase AlphaFold + ColabFold –
GO:0016747Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
0.36 No Hit 0.0% —
4718 KP13_05078 hypothetical protein ColabFold – – 0.255 No Hit 0.0% —
4719 KP13_05079 hypothetical protein ColabFold – – 0.662 No Hit 0.0% —
4720 KP13_05082 Alpha-acetolactate decarboxylase budA AlphaFold + ColabFold
4.1.1.5
GO:0047605Catalysis of the reaction: (S)-2-hydroxy-2-methyl-3-oxobutanoate = (R)-2-acetoin + CO2. GO:0045151The chemical reactions and pathways resulting in the formation of acetoin, 3-hydroxy-2-butanone.
0.298 No Hit 0.0% —
4721 KP13_05083 HTH-type transcriptional regulator budR AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. GO:0032993A macromolecular complex containing both protein and DNA molecules. +14 total
0.286 No Hit 0.0% —
4722 KP13_05085 putative D-beta-hydroxy butyrate permease AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0015128Enables the transfer of gluconate from one side of a membrane to the other. Gluconate is the aldonic acid derived from glucose. GO:0035429The process in which gluconate is transported across a membrane. Gluconate is the aldonic acid derived from glucose. +14 total
0.794 No Hit 0.0% —
4723 KP13_05090 putative LysR family transcriptional regulator AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +14 total
0.687 No Hit 0.0% —
4724 KP13_05091 hypothetical protein ColabFold – – 0.7 No Hit 0.0% —
4725 KP13_05092 hypothetical protein AlphaFold + ColabFold –
GO:0006974Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
0.464 No Hit 0.0% —
Page of 234 · 5842 total proteins