Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 / 5842 proteins

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# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
4826 KP13_05233 Purine ribonucleoside efflux pump nepI AlphaFold + ColabFold –
GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
0.992 No Hit 0.0% —
4827 KP13_05234 AraC family transcriptional regulator AlphaFold + ColabFold –
GO:0043565Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
0.369 No Hit 0.0% —
4828 KP13_05235 hypothetical protein AlphaFold + ColabFold – – 0.862 No Hit 0.0% —
4829 KP13_05236 hypothetical protein AlphaFold + ColabFold – – 0.089 No Hit 0.0% —
4830 KP13_05237 hypothetical protein AlphaFold + ColabFold –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.517 No Hit 0.0% —
4831 KP13_05238 Oxidoreductase, 2OG-Fe(II) oxygenase family protein AlphaFold + ColabFold
1.13.12.19 1.14.20.7
GO:0102276Catalysis of the reaction: 2-oxoglutarate(2-) + O2 + 2 H+ = ethene + 3 carbon dioxide + H2O. GO:0046872Binding to a metal ion. GO:0009693The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.
0.576 No Hit 0.0% —
4832 KP13_05239 D-methionine transport system substrate-binding protein AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
0.405 No Hit 0.0% —
4833 KP13_05241 putative D-methionine transport system permease protein metI AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +14 total
0.871 No Hit 0.0% —
4834 KP13_05242 putative 2-nitropropane dioxygenase AlphaFold + ColabFold –
GO:0018580Catalysis of the reaction: ethylnitronate + O2 = acetaldehyde + nitrite. GO:0051213Catalysis of the incorporation of both atoms of molecular oxygen (O2) into the substrate. GO:0000166Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. +14 total
0.732 No Hit 0.0% —
4835 KP13_05243 LysR family transcriptional regulator AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. GO:0000976Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
0.658 No Hit 0.0% —
4836 KP13_05244 putative sugar transport protein AlphaFold + ColabFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
0.855 No Hit 0.0% —
4837 KP13_05245 Putative prolyl endopeptidase AlphaFold + ColabFold – – 0.564 No Hit 0.0% —
4838 KP13_05246 MFS family transporter AlphaFold + ColabFold –
GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
0.976 No Hit 0.0% —
4839 KP13_05248 hypothetical protein AlphaFold + ColabFold – – 0.235 No Hit 0.0% —
4840 KP13_05249 Trans-aconitate 2-methyltransferase tam AlphaFold + ColabFold
2.1.1.144
GO:0030798Catalysis of the reaction: S-adenosyl-L-methionine + trans-aconitate = (E)-3-(methoxycarbonyl)pent-2-enedioate + S-adenosyl-L-homocysteine. GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0032259The process in which a methyl group is covalently attached to a molecule.
0.978 No Hit 0.0% —
4841 KP13_05250 putative carboxymuconolactone decarboxylase AlphaFold + ColabFold –
GO:0051920Catalysis of the reaction: [protein]-dithol + ROOH = [protein]-disulfide + H2O + ROH.
0.158 No Hit 0.0% —
4842 KP13_05251 hypothetical protein AlphaFold + ColabFold – – 0.305 No Hit 0.0% —
4843 KP13_05252 Putative type VI secretion system effector, Hcp1 family ColabFold – – 0.107 No Hit 0.0% —
4844 KP13_05253 hypothetical protein AlphaFold + ColabFold – – 0.702 No Hit 0.0% —
4845 KP13_05254 hypothetical protein AlphaFold + ColabFold – – 0.712 No Hit 0.0% —
4846 KP13_05255 hypothetical protein AlphaFold + ColabFold – – 0.155 No Hit 0.0% —
4847 KP13_05257 Altronate oxidoreductase uxaB AlphaFold + ColabFold
1.1.1.58
GO:0009026Catalysis of the reaction: D-altronate + NAD+ = D-tagaturonate + H+ + NADH. GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +36 total
0.328 No Hit 0.0% —
4848 KP13_05258 putative acyltransferase AlphaFold + ColabFold –
GO:0016747Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
0.203 No Hit 0.0% —
4849 KP13_05259 putative transport protein AlphaFold + ColabFold
2.7.7.65
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0052621Catalysis of the reaction: 2 GTP = cyclic di-3',5'-guanylate + 2 diphosphate + 2 H+. GO:0005525Binding to GTP, guanosine triphosphate. +25 total
0.663 No Hit 0.0% —
4850 KP13_05260 hypothetical protein AlphaFold + ColabFold – – 0.497 No Hit 0.0% —
Page of 234 · 5842 total proteins