Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 / 5842 proteins

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# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
5151 KP13_05726 hypothetical protein AlphaFold + ColabFold – – 0.393 No Hit 0.0% —
5152 KP13_05734 hypothetical protein AlphaFold + ColabFold – – 0.415 No Hit 0.0% —
5153 KP13_05739 hypothetical protein AlphaFold + ColabFold – – 0.35 No Hit 0.0% —
5154 KP13_05740 endonuclease_MobA/VirD2 family protein virD2 AlphaFold + ColabFold – – 0.847 No Hit 0.0% —
5155 KP13_05741 bacterial antitermination protein NusG AlphaFold + ColabFold –
GO:0140673A chromatin remodeling process that reestablishes the chromatin structure following the passage of RNA polymerase II during transcription elongation, thus preventing cryptic transcription initiation. GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0006354The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase.
0.91 No Hit 0.0% —
5156 KP13_05747 hypothetical protein ColabFold – – 0.32 No Hit 0.0% —
5157 KP13_05761 hypothetical protein ColabFold – – 0.352 No Hit 0.0% —
5158 KP13_05763 hypothetical protein AlphaFold + ColabFold – – 0.817 No Hit 0.0% —
5159 KP13_05770 Major outer membrane lipoprotein lpp AlphaFold + ColabFold –
GO:0019867The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites. GO:0009279A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures. GO:0008289Binding to a lipid. +36 total
0.521 No Hit 0.0% —
5160 KP13_05784 hypothetical protein AlphaFold + ColabFold –
GO:0043022Binding to a ribosome. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
0.17 No Hit 0.0% —
5161 KP13_05807 hypothetical protein AlphaFold + ColabFold – – 0.677 No Hit 0.0% —
5162 KP13_05810 hypothetical protein ColabFold – – 0.821 No Hit 0.0% —
5163 KP13_05828 Zinc metalloproteinase Mpr protein AlphaFold + ColabFold –
GO:0006950Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
0.521 No Hit 0.0% —
5164 KP13_05830 hypothetical protein AlphaFold + ColabFold – – 0.455 No Hit 0.0% —
5165 KP13_05837 hypothetical protein ColabFold – – 0.348 No Hit 0.0% —
5166 KP13_05921 hypothetical protein AlphaFold + ColabFold – – 0.548 No Hit 0.0% —
5167 KP13_05940 insertion element IS1 protein insA AlphaFold + ColabFold –
GO:0006313A type of transposition in which a transposable element (transposon) is moved to another part of a genome, either by a cut-and-paste mechanism or a replicative mechanism.
0.438 No Hit 0.0% —
5168 KP13_05944 transposase for insertion sequence-like element IS431mec AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
0.584 No Hit 0.0% —
5169 KP13_05968 hypothetical protein AlphaFold + ColabFold – – 0.369 No Hit 0.0% —
5170 KP13_05969 hypothetical protein AlphaFold + ColabFold – – 0.228 No Hit 0.0% —
5171 KP13_06036 hypothetical protein AlphaFold + ColabFold – – 0.001 No Hit 0.0% —
5172 KP13_06058 hypothetical protein ColabFold – – 0.539 No Hit 0.0% —
5173 KP13_06084 hypothetical protein AlphaFold + ColabFold –
GO:0006260The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA. GO:0003887Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.615 No Hit 0.0% —
5174 KP13_06138 Thiol:disulfide interchange protein dsbA AlphaFold + ColabFold –
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0042597The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria). GO:0015036Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds. +14 total
0.38 No Hit 0.0% —
5175 KP13_06160 hypothetical protein AlphaFold + ColabFold – – 0.648 No Hit 0.0% —
Page of 234 · 5842 total proteins