Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 / 5842 proteins

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# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
1726 KP13_00694 Haloacid dehydrogenase/epoxide hydrolase AlphaFold + ColabFold – – 0.755 No Hit 0.0% —
1727 KP13_00697 Penicillin-binding protein 1A mrcA AlphaFold + ColabFold
2.4.99.28 3.4.16.4
GO:0008658Binding to penicillin, an antibiotic that contains the condensed beta-lactamthiazolidine ring system. GO:0030288The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +710 total
0.568 No Hit 0.0% —
1728 KP13_00698 hypothetical protein AlphaFold + ColabFold – – 0.669 No Hit 0.0% —
1729 KP13_00699 hypothetical protein AlphaFold + ColabFold – – 0.715 No Hit 0.0% —
1730 KP13_00700 hypothetical protein ColabFold – – 0.23 No Hit 0.0% —
1731 KP13_00701 hypothetical protein AlphaFold + ColabFold – – 0.45 No Hit 0.0% —
1732 KP13_00702 Protein transport protein hofQ hofQ AlphaFold + ColabFold –
GO:0009306The controlled release of proteins from a cell. GO:0009279A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.
0.811 No Hit 0.0% —
1733 KP13_00705 Protein damX damX AlphaFold + ColabFold –
GO:0042834Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls. GO:0030428A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells. GO:0032506A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells).
0.103 No Hit 0.0% —
1734 KP13_00706 DNA adenine methylase dam AlphaFold + ColabFold
2.1.1.72
GO:0009007Catalysis of the reaction: S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine. GO:0008168Catalysis of the transfer of a methyl group to an acceptor molecule. GO:0003676Binding to a nucleic acid. +710 total
0.386 No Hit 0.0% —
1735 KP13_00708 Phosphoglycolate phosphatase gph AlphaFold + ColabFold
3.1.3.18
GO:0008967Catalysis of the reaction: 2-phosphoglycolate + H2O = glycolate + phosphate. GO:0005975The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +36 total
0.896 No Hit 0.0% —
1736 KP13_00710 Siroheme synthase 2 cysG2 AlphaFold + ColabFold –
GO:0004851Catalysis of the reaction: uroporphyrinogen III + 2 S-adenosyl-L-methionine = precorrin-2 + 2 S-adenosyl-L-homocysteine + H+. GO:0051266Catalysis of the reaction: siroheme + 2 H+ = Fe(2+) + sirohydrochlorin. GO:0008168Catalysis of the transfer of a methyl group to an acceptor molecule. +58 total
0.579 No Hit 0.0% —
1737 KP13_00711 Nitrite reductase [NAD(P)H] small subunit nirD AlphaFold + ColabFold
1.7.1.15
GO:0051537Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands. GO:0008942Catalysis of the reaction: NH4+ + 3 NAD(P)+ + 2 H2O = nitrite + 3 NAD(P)H + 5 H+. GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. +36 total
0.105 No Hit 0.0% —
1738 KP13_00713 hypothetical protein AlphaFold + ColabFold – – 0.717 No Hit 0.0% —
1739 KP13_00714 Cytosine deaminase codA AlphaFold + ColabFold –
GO:0016810Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds. GO:0004131Catalysis of the reaction: cytosine + H2O = uracil + NH4+. GO:0035888Catalysis of the reaction: H+ + H2O + isoguanine = NH4+ + xanthine. +25 total
0.287 No Hit 0.0% —
1740 KP13_00715 TsgA-like protein AlphaFold + ColabFold –
GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
0.548 No Hit 0.0% —
1741 KP13_00716 hypothetical protein ColabFold – – 0.484 No Hit 0.0% —
1742 KP13_00718 hypothetical protein AlphaFold + ColabFold – – 0.511 No Hit 0.0% —
1743 KP13_00719 putative adenosine monophosphate-protein transferase fic fic AlphaFold + ColabFold
2.7.7.108
GO:0070733Catalysis of the reaction: ATP + protein = diphosphate + adenylyl-protein; mediates the addition of an adenylyl (adenosine 5'-monophosphate; AMP group) to L-serine, L-threonine, and L-tyrosine residues in target proteins. GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0051302Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.
0.316 No Hit 0.0% —
1744 KP13_00722 Fusaric acid resistance protein AlphaFold + ColabFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
0.997 No Hit 0.0% —
1745 KP13_00724 hypothetical protein AlphaFold + ColabFold – – 0.585 No Hit 0.0% —
1746 KP13_00725 putative phosphoribulokinase prkB AlphaFold + ColabFold
2.7.1.19
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0005975The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. GO:0016301Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. +14 total
0.061 No Hit 0.0% —
1747 KP13_00726 hypothetical protein AlphaFold + ColabFold – – 0.414 No Hit 0.0% —
1748 KP13_00732 hypothetical protein AlphaFold + ColabFold – – 0.411 No Hit 0.0% —
1749 KP13_00733 FKBP-type peptidyl-prolyl cis-trans isomerase slyD slyD AlphaFold + ColabFold
5.2.1.8
GO:0003755Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0). GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0046872Binding to a metal ion. +14 total
0.651 No Hit 0.0% —
1750 KP13_00734 Protein slyX slyX AlphaFold + ColabFold – – 0.919 No Hit 0.0% —
Page of 234 · 5842 total proteins