Proteins

Genome: NC_002516.2

Description: Pseudomonas aeruginosa PAO1, complete genome

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3 / 5572 proteins

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Applied filters EC Number: 2.5.1.3

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EC Number: 2.5.1.3 ×
# Protein Description Gene Structure EC GO Metabolism Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
1 PA5358 4-hydroxybenzoate octaprenyltransferase ubiA, PA5358 AlphaFold DB model
2.5.1.39
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0008412Catalysis of the reaction: 4-hydroxybenzoate + an all-trans-polyprenyl diphosphate = a 4-hydroxy-3-all-trans-polyprenylbenzoate + diphosphate. GO:0006744The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme. +36 total
No map 0.805 Hit 40.1% 1.08e-27
2 PA3652 ditrans,polycis-undecaprenyl-diphosphate synthase uppS, PA3652 AlphaFold DB model
2.5.1.31
GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0008834Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 8 isopentenyl diphosphate = di-trans,octa-cis-undecaprenyl diphosphate + 8 diphosphate. GO:0000287Binding to a magnesium (Mg) ion. +58 total
No map 0.737 Hit 46.6% 9.21e-10
3 PA3976 thiamine-phosphate pyrophosphorylase PA3976, thiE AlphaFold DB model
2.5.1.3
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0000287Binding to a magnesium (Mg) ion. GO:0004789Catalysis of the reaction: 4-amino-2-methyl-5-diphosphomethylpyrimidine + 4-methyl-5-(2-phosphoethyl)-thiazole + H+ = diphosphate + thiamine phosphate. +25 total
No map 0.592 No Hit N/A —
Page 1 of 1 · 3 total proteins