Proteins

Genome: NC_002516.2

Description: Pseudomonas aeruginosa PAO1, complete genome

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7 / 5572 proteins

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Applied filters EC Number: 2.7.1.2

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EC Number: 2.7.1.2 ×
# Protein Description Gene Structure EC GO Metabolism Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
1 PA5009 lipopolysaccharide kinase WaaP waaP, rfaP, PA5009 Experimental + AlphaFold DB model
2.7.1.235 2.7.10.2
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016301Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. +36 total
No map 0.941 No Hit N/A —
2 PA3560 PTS system fructose-specific transporter subunit IIBC PA3560, fruA AlphaFold DB model
2.7.1.202
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0005351Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: carbohydrate(out) + H+(out) = carbohydrate(in) + H+(in). GO:0016301Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. +58 total
No map 0.837 No Hit N/A —
3 PA3088 NAD kinase nadK, PA3088 Experimental + AlphaFold DB model
2.7.1.23
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0046872Binding to a metal ion. +47 total
No map 0.699 Hit 28.5% 2.54e-28
4 PA3193 glucokinase glk, PA3193 AlphaFold DB model
2.7.1.2
GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0005536Binding to D-enantiomers of glucose. +36 total
No map 0.658 No Hit N/A —
5 PA0596 hypothetical protein PA0596, amgK AlphaFold DB model
2.7.1.221
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016301Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. GO:0071555A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. +47 total
No map 0.65 No Hit N/A —
6 PA1393 adenylyl-sulfate kinase cysC, PA1393 AlphaFold DB model
2.7.1.25
GO:0004020Catalysis of the reaction: adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate + ADP + H+. GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0070814The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S. +14 total
No map 0.388 Hit 50.0% 1.66e-47
7 PA4529 dephospho-CoA kinase PA4529, coaE AlphaFold DB model
2.7.1.24
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0004140Catalysis of the reaction: 3'-dephospho-CoA + ATP = ADP + CoA + 2 H+. +14 total
No map 0.338 Hit 43.8% 9.97e-22
Page 1 of 1 · 7 total proteins