KEGG:map00760

Nicotinate and nicotinamide metabolism

KpATCC43816 - Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome

All pathways Protein ranking
Reactions 15
Proteins 12
Metabolites 31
Chokepoints 4

Pathway map

Reaction-to-metabolite flow reconstructed from the imported SBML participants.

Chokepoint reaction Metabolite ⇌ Reversible reaction Currency metabolites hidden
Computing layout…

Connected pathways

Other pathways in this genome that share reactions with this one.

MODEL Unassigned metabolic reactions 39 shared KEGG Pentose phosphate pathway 4 shared KEGG Fructose and mannose metabolism 3 shared KEGG Porphyrin metabolism 2 shared KEGG Glycerolipid metabolism 2 shared KEGG Glycolysis / Gluconeogenesis 2 shared KEGG Histidine metabolism 2 shared KEGG Inositol phosphate metabolism 1 shared KEGG Arginine biosynthesis 1 shared KEGG Carbon fixation by Calvin cycle 1 shared KEGG Alanine, aspartate and glutamate metabolism 1 shared

Reaction table

Catalyzed reactions, mapped genes, and SBML substrates/products.

2.7.7.1-RXN

EC 2.7.7.1 · R00137 · 2.7.7.1-RXN · not reversible

beta-nicotinamide D-ribonucleotide ATP H+
→
NAD+ diphosphate
VK055_2586

NAD-SYNTH-GLN-RXN

EC 6.3.5.1 · R00257 · NAD-SYNTH-GLN-RXN · not reversible

L-glutamine nicotinate adenine dinucleotide ATP H2O
→
L-glutamate AMP H+ NAD+ diphosphate
No mapped protein

NICONUCADENYLYLTRAN-RXN

EC 2.7.7.18 · R03005 · NICONUCADENYLYLTRAN-RXN · not reversible

producing
beta-nicotinate D-ribonucleotide ATP H+
→
nicotinate adenine dinucleotide diphosphate
VK055_1861

NICOTINATEPRIBOSYLTRANS-RXN

EC 6.3.4.21 · R01724 · NICOTINATEPRIBOSYLTRANS-RXN · not reversible

consuming
5-phospho-alpha-D-ribose 1-diphosphate nicotinate ATP H2O
→
beta-nicotinate D-ribonucleotide ADP diphosphate phosphate
VK055_1520

QUINOPRIBOTRANS-RXN

EC 2.4.2.19 · R03348 · QUINOPRIBOTRANS-RXN · not reversible

consuming
5-phospho-alpha-D-ribose 1-diphosphate quinolinate H+
→
beta-nicotinate D-ribonucleotide CO2 diphosphate
VK055_2460

RIBOSYLNICOTINAMIDE-KINASE-RXN

EC 2.7.1.22 · R02324 · RIBOSYLNICOTINAMIDE-KINASE-RXN · not reversible

1-(beta-D ribofuranosyl)nicotinamide ATP
→
beta-nicotinamide D-ribonucleotide ADP H+
No mapped protein

RXN-14227

EC 3.1.3.5 · R03346 · RXN-14227 · not reversible

beta-nicotinate D-ribonucleotide H2O
→
beta-D-ribosylnicotinate phosphate
VK055_4410

RXN-5841

EC 3.1.3.5 · R02323 · RXN-5841 · not reversible

beta-nicotinamide D-ribonucleotide H2O
→
1-(beta-D ribofuranosyl)nicotinamide phosphate
VK055_4410

SUCCSEMIALDDEHYDROG-RXN

EC 1.2.1.79 · R00714 · SUCCSEMIALDDEHYDROG-RXN · not reversible

succinate semialdehyde H2O NADP+
→
succinate H+ NADPH
No mapped protein