Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 proteins

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# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
3326 KP13_02523 putative MFS-type transporter AlphaFold + ColabFold –
GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
0.49 No Hit 0.0% —
3327 KP13_00949 Thiamine biosynthesis lipoprotein apbE apbE AlphaFold + ColabFold
2.7.1.180
GO:0017013The addition of a flavin group to a protein amino acid. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0046872Binding to a metal ion. +14 total
0.49 No Hit 0.0% —
3328 KP13_31599 putative Gcn5-related acetyltransferase AlphaFold + ColabFold –
GO:0016747Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
0.489 No Hit 0.0% —
3329 KP13_05669 hypothetical protein AlphaFold + ColabFold – – 0.489 No Hit 0.0% —
3330 KP13_04813 Type IV secretion system protein virB1 virB1 AlphaFold + ColabFold – – 0.489 No Hit 0.0% —
3331 KP13_04749 Cobalamin synthase cobS AlphaFold + ColabFold
2.7.8.26
GO:0008818Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole-5'-phosphate = adenosylcobalamin-5'-phosphate + GMP. GO:0051073Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole = GMP + adenosylcobalamin. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +14 total
0.489 No Hit 0.0% —
3332 KP13_02904 hypothetical protein AlphaFold + ColabFold – – 0.489 No Hit 0.0% —
3333 KP13_01317 hypothetical protein AlphaFold + ColabFold – – 0.489 No Hit 0.0% —
3334 KP13_00954 Sensor kinase protein rcsC rcsC AlphaFold + ColabFold
2.7.13.3
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0018106The phosphorylation of peptidyl-histidine to form peptidyl-1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine) or peptidyl-3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine). GO:0016310The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. +811 total
0.489 No Hit 0.0% —
3335 KP13_00675 hypothetical protein ColabFold – – 0.489 No Hit 0.0% —
3336 KP13_31916 hypothetical protein AlphaFold + ColabFold – – 0.488 No Hit 0.0% —
3337 KP13_07626 Protocatechuate 4,5-dioxygenase beta chain AlphaFold + ColabFold –
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0008198Binding to a ferrous iron ion, Fe(II). GO:0006725OBSOLETE. The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells. +14 total
0.488 No Hit 0.0% —
3338 KP13_04274 hypothetical protein ColabFold – – 0.488 No Hit 0.0% —
3339 KP13_01628 hypothetical protein ColabFold – – 0.488 No Hit 0.0% —
3340 KP13_01413 Plasmid stability protein B parB AlphaFold + ColabFold – – 0.488 No Hit 0.0% —
3341 KP13_01057 Lysozyme-related protein AlphaFold + ColabFold – – 0.488 No Hit 0.0% —
3342 KP13_00305 Glutathione reductase gor AlphaFold + ColabFold –
GO:0006749The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. GO:0016668Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces NAD or NADP. GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. +47 total
0.488 Hit 54.3% 5.18e-161
3343 KP13_32242 Type II secretion system protein E AlphaFold + ColabFold –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
0.487 No Hit 0.0% —
3344 KP13_31632 Na(+)-translocating NADH-quinone reductase subunit A nqrA AlphaFold + ColabFold
7.2.1.1
GO:0016655Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule. GO:0006814The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
0.487 No Hit 0.0% —
3345 KP13_07162 Ribosomal RNA small subunit methyltransferase G rsmG AlphaFold + ColabFold
2.1.1.170
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0008649Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an rRNA molecule. The methyl group can be transfered to the nucleobase or to the ribose group of the nucleoside. GO:0006364Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. +25 total
0.487 No Hit 0.0% —
3346 KP13_03817 DNA replication initiation factor hda AlphaFold + ColabFold –
GO:0032297Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication.
0.487 No Hit 0.0% —
3347 KP13_01760 hypothetical protein AlphaFold + ColabFold – – 0.487 No Hit 0.0% —
3348 KP13_00020 ATP synthase subunit c atpE AlphaFold + ColabFold –
GO:0015078Enables the transfer of a proton from one side of a membrane to the other. GO:1902600The directed movement of a proton across a membrane. GO:0015986The chemical reactions and pathways resulting in the formation of ATP driven by transport of protons across a membrane to generate an electrochemical gradient (proton-motive force). +69 total
0.487 No Hit 0.0% —
3349 KP13_04795 hypothetical protein ColabFold – – 0.486 No Hit 0.0% —
3350 KP13_04527 Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit fdnH AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0015944The chemical reactions and pathways by which formate is converted to CO2. GO:0045333The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration). +69 total
0.486 No Hit 0.0% —
Page of 234 · 5842 total proteins