Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 / 5842 proteins

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# Protein Description Gene Structure EC GO Metabolism Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
3976 KP13_04062 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.095 No Hit 0.0% —
3977 KP13_04063 Antibiotic biosynthesis monooxygenase AlphaFold DB model + ColabFold model –
GO:0004497Catalysis of the incorporation of one atom of molecular oxygen (O2) into the substrate and the reduction of the other atom of O2 to water.
No map 0.865 No Hit 0.0% —
3978 KP13_04064 Glyoxalase/bleomycin resistance protein/dioxygenase AlphaFold DB model + ColabFold model –
GO:0051213Catalysis of the incorporation of both atoms of molecular oxygen (O2) into the substrate.
No map 0.293 No Hit 0.0% —
3979 KP13_04065 HTH-type transcriptional regulator betI betI AlphaFold DB model + ColabFold model –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
No map 0.954 No Hit 0.0% —
3980 KP13_04066 OsmC-like protein AlphaFold DB model + ColabFold model – – No map 0.104 No Hit 0.0% —
3981 KP13_04067 Isochorismatase-like protein AlphaFold DB model + ColabFold model
3.-.-.-
GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
No map 0.379 No Hit 0.0% —
3982 KP13_04068 hypothetical protein ColabFold model – – No map 0.208 No Hit 0.0% —
3983 KP13_04070 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.16 No Hit 0.0% —
3984 KP13_04071 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.42 No Hit 0.0% —
3985 KP13_04072 hypothetical protein Experimental + ColabFold model –
GO:0046872Binding to a metal ion.
No map 0.865 No Hit 0.0% —
3986 KP13_04073 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.395 No Hit 0.0% —
3987 KP13_04074 putative manganese catalase AlphaFold DB model + ColabFold model –
GO:0046872Binding to a metal ion.
No map 0.375 No Hit 0.0% —
3988 KP13_04075 Cytochrome oxidase bd-II, subunit 1 AlphaFold DB model + ColabFold model –
GO:0019646A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to oxygen to generate a transmembrane electrochemical gradient. GO:0009055A molecular function representing the directed movement of electrons from one molecular entity to another, typically mediated by electron carriers or acceptors, resulting in the transfer of energy and/or the reduction-oxidation (redox) transformation of chemical species. This activity is fundamental to various biological processes, including cellular respiration and photosynthesis, as well as numerous enzymatic reactions involved in metabolic pathways. GO:0070069A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.
No map 1 No Hit 0.0% —
3989 KP13_04076 Cytochrome d ubiquinol oxidase subunit 2 AlphaFold DB model + ColabFold model –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0070069A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +36 total
No map 0.976 No Hit 0.0% —
3990 KP13_04077 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.794 No Hit 0.0% —
3991 KP13_04078 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.316 No Hit 0.0% —
3992 KP13_04079 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.655 No Hit 0.0% —
3993 KP13_04080 hypothetical protein ColabFold model – – No map 0.567 No Hit 0.0% —
3994 KP13_04081 cyclic diguanylate phosphodiesterase domain-containing protein AlphaFold DB model + ColabFold model – – No map 0.183 No Hit 0.0% —
3995 KP13_04082 carboxylyase-related protein Experimental + ColabFold model –
GO:0016831Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound.
No map 0.858 No Hit 0.0% —
3996 KP13_04083 HTH-type transcriptional regulator budR budR AlphaFold DB model + ColabFold model –
GO:0032993A macromolecular complex containing both protein and DNA molecules. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
No map 0.632 No Hit 0.0% —
3997 KP13_04084 putative diguanylate cyclase AlphaFold DB model + ColabFold model
2.7.7.65
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0007165The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +58 total
No map 0.564 No Hit 0.0% —
3998 KP13_04085 Metal-dependent phosphohydrolase AlphaFold DB model + ColabFold model – – No map 0.538 No Hit 0.0% —
3999 KP13_04086 L-asparaginase ansB AlphaFold DB model + ColabFold model –
GO:0006520The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups. GO:0004067Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH4+. GO:0006528The chemical reactions and pathways involving asparagine, 2-amino-3-carbamoylpropanoic acid.
No map 0.344 No Hit 0.0% —
4000 KP13_04087 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.512 No Hit 0.0% —
Page of 234 · 5842 total proteins