Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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# Protein Description Gene Structure EC GO Metabolism Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
5801 KP13_04460 Cytochrome bd-II oxidase subunit 2 appB AlphaFold DB model + ColabFold model –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0070069A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +36 total
No map 0.999 No Hit 0.0% —
5802 KP13_04461 Cytochrome d ubiquinol oxidase subunit 1 AlphaFold DB model + ColabFold model –
GO:0019646A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to oxygen to generate a transmembrane electrochemical gradient. GO:0009055A molecular function representing the directed movement of electrons from one molecular entity to another, typically mediated by electron carriers or acceptors, resulting in the transfer of energy and/or the reduction-oxidation (redox) transformation of chemical species. This activity is fundamental to various biological processes, including cellular respiration and photosynthesis, as well as numerous enzymatic reactions involved in metabolic pathways. GO:0070069A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions. +47 total
No map 0.999 No Hit 0.0% —
5803 KP13_04466 Inner membrane ABC transporter permease protein AlphaFold DB model + ColabFold model –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
No map 0.999 No Hit 0.0% —
5804 KP13_04509 Respiratory nitrate reductase 2 gamma chain narV AlphaFold DB model + ColabFold model
1.7.5.1
GO:0009325An enzyme complex that catalyzes the formation of nitrate from nitrite with the concomitant reduction of an acceptor. GO:0008940Catalysis of the reaction: nitrite + acceptor = nitrate + reduced acceptor. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +69 total
No map 0.999 No Hit 0.0% —
5805 KP13_05362 Putative tartrate transporter ttuB AlphaFold DB model + ColabFold model –
GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
No map 0.999 Hit 22.4% 2.74e-16
5806 KP13_05500 putative multidrug resistance transporter AlphaFold DB model + ColabFold model –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. +14 total
No map 0.999 No Hit 0.0% —
5807 KP13_00914 hypothetical protein AlphaFold DB model + ColabFold model – – No map 1 No Hit 0.0% —
5808 KP13_02971 hypothetical protein AlphaFold DB model + ColabFold model – – No map 1 No Hit 0.0% —
5809 KP13_03694 hypothetical protein AlphaFold DB model + ColabFold model –
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0008202The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
No map 1 No Hit 0.0% —
5810 KP13_04075 Cytochrome oxidase bd-II, subunit 1 AlphaFold DB model + ColabFold model –
GO:0019646A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to oxygen to generate a transmembrane electrochemical gradient. GO:0009055A molecular function representing the directed movement of electrons from one molecular entity to another, typically mediated by electron carriers or acceptors, resulting in the transfer of energy and/or the reduction-oxidation (redox) transformation of chemical species. This activity is fundamental to various biological processes, including cellular respiration and photosynthesis, as well as numerous enzymatic reactions involved in metabolic pathways. GO:0070069A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.
No map 1 No Hit 0.0% —
5811 KP13_04940 N-methyl-L-tryptophan oxidase solA AlphaFold DB model + ColabFold model
1.5.3.-
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0050131Catalysis of the reaction: an N-methyl-L-amino acid + H2O + O2 = an L-amino acid + formaldehyde + H2O2. GO:0050660Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2. +25 total
No map 1 Hit 30.0% 2.52e-44
5812 KP13_05137 Cyclopropane-fatty-acyl-phospholipid synthase AlphaFold DB model + ColabFold model –
GO:0008610The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. GO:0008168Catalysis of the transfer of a methyl group to an acceptor molecule. GO:0032259The process in which a methyl group is covalently attached to a molecule.
No map 1 No Hit 0.0% —
5813 KP13_05305 Cytochrome c-type biogenesis protein ccmF ccmF AlphaFold DB model + ColabFold model –
GO:0015232Enables the transfer of heme from one side of a membrane to the other. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0015886The directed movement of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. +36 total
No map 1 No Hit 0.0% —
5814 KP13_05320 Formate dehydrogenase H fdhF AlphaFold DB model + ColabFold model –
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0015942The chemical reactions and pathways involving formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid. GO:0008863Catalysis of the reaction: formate + NAD+ = CO2 + NADH. +710 total
No map 1 No Hit 0.0% —
5815 KP13_07105 hypothetical protein AlphaFold DB model + ColabFold model – – No map 1 No Hit 0.0% —
5816 KP13_32152 Quinoprotein glucose dehydrogenase gcd AlphaFold DB model + ColabFold model –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0016614Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. GO:0030288The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall. +36 total
No map 1 No Hit 0.0% —
5817 KP13_31919 hypothetical protein ColabFold model – – No map No pocket No Hit 0.0% —
5818 KP13_05094 putative chromate transporter AlphaFold DB model + ColabFold model – – No map No pocket No Hit 0.0% —
5819 KP13_31907 hypothetical protein AlphaFold DB model + ColabFold model – – No map No pocket No Hit 0.0% —
5820 KP13_00792 hypothetical protein ColabFold model – – No map No pocket No Hit 0.0% —
5821 KP13_03125 hypothetical protein AlphaFold DB model + ColabFold model – – No map No pocket No Hit 0.0% —
5822 KP13_02136 hypothetical protein AlphaFold DB model + ColabFold model – – No map No pocket No Hit 0.0% —
5823 KP13_32395 hypothetical protein ColabFold model – – No map No pocket No Hit 0.0% —
5824 KP13_00884 hypothetical protein ColabFold model – – No map No pocket No Hit 0.0% —
5825 KP13_04807 hypothetical protein AlphaFold DB model + ColabFold model – – No map No pocket No Hit 0.0% —
Page of 234 · 5842 total proteins