Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 / 5842 proteins

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Rows
# Protein Description Gene Structure EC GO Metabolism Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
676 KP13_05940 insertion element IS1 protein insA AlphaFold DB model + ColabFold model –
GO:0006313A type of transposition in which a transposable element (transposon) is moved to another part of a genome, either by a cut-and-paste mechanism or a replicative mechanism.
No map 0.438 No Hit 0.0% —
677 KP13_05921 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.548 No Hit 0.0% —
678 KP13_05837 hypothetical protein ColabFold model – – No map 0.348 No Hit 0.0% —
679 KP13_05830 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.455 No Hit 0.0% —
680 KP13_05828 Zinc metalloproteinase Mpr protein AlphaFold DB model + ColabFold model –
GO:0006950Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
No map 0.521 No Hit 0.0% —
681 KP13_05810 hypothetical protein ColabFold model – – No map 0.821 No Hit 0.0% —
682 KP13_05807 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.677 No Hit 0.0% —
683 KP13_05784 hypothetical protein AlphaFold DB model + ColabFold model –
GO:0043022Binding to a ribosome. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
No map 0.17 No Hit 0.0% —
684 KP13_05770 Major outer membrane lipoprotein lpp AlphaFold DB model + ColabFold model –
GO:0019867The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites. GO:0009279A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures. GO:0008289Binding to a lipid. +36 total
No map 0.521 No Hit 0.0% —
685 KP13_05763 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.817 No Hit 0.0% —
686 KP13_05761 hypothetical protein ColabFold model – – No map 0.352 No Hit 0.0% —
687 KP13_05747 hypothetical protein ColabFold model – – No map 0.32 No Hit 0.0% —
688 KP13_05741 bacterial antitermination protein NusG AlphaFold DB model + ColabFold model –
GO:0140673A chromatin remodeling process that reestablishes the chromatin structure following the passage of RNA polymerase II during transcription elongation, thus preventing cryptic transcription initiation. GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0006354The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase.
No map 0.91 No Hit 0.0% —
689 KP13_05740 endonuclease_MobA/VirD2 family protein virD2 AlphaFold DB model + ColabFold model – – No map 0.847 No Hit 0.0% —
690 KP13_05739 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.35 No Hit 0.0% —
691 KP13_05734 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.415 No Hit 0.0% —
692 KP13_05726 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.393 No Hit 0.0% —
693 KP13_05720 Resolvase AlphaFold DB model + ColabFold model –
GO:0000150Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA. GO:0006310Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
No map 0.394 No Hit 0.0% —
694 KP13_05719 Propanediol utilization protein pduA AlphaFold DB model + ColabFold model –
GO:0031469An organelle found in bacteria consisting of a proteinaceous coat containing metabolic enzymes whose purpose is the sequestration or concentration of metabolites and which has the appearance of a polygonal granule by electron microscopy.
No map 0.532 No Hit 0.0% —
695 KP13_05711 hypothetical protein ColabFold model – – No map 0.565 No Hit 0.0% —
696 KP13_05699 Transposon Tn3 resolvase AlphaFold DB model + ColabFold model –
GO:0000150Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA. GO:0006310Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). +14 total
No map 0.409 No Hit 0.0% —
697 KP13_05698 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.37 No Hit 0.0% —
698 KP13_05697 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.211 No Hit 0.0% —
699 KP13_05682 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.562 No Hit 0.0% —
700 KP13_05672 putative transposase AlphaFold DB model + ColabFold model –
GO:0004803Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element. GO:0006313A type of transposition in which a transposable element (transposon) is moved to another part of a genome, either by a cut-and-paste mechanism or a replicative mechanism.
No map 0.739 No Hit 0.0% —
Page of 234 · 5842 total proteins