Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 proteins

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Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
51 KP13_32207 hypothetical protein AlphaFold + ColabFold – – 0.329 No Hit 0.0% —
52 KP13_32206 membrane protein insertion efficiency factor AlphaFold + ColabFold – – 0.978 No Hit 0.0% —
53 KP13_32205 multidrug resistance protein mdtL AlphaFold + ColabFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
0.78 No Hit 0.0% —
54 KP13_32204 hypothetical protein AlphaFold + ColabFold – – 0.828 No Hit 0.0% —
55 KP13_32203 hypothetical protein AlphaFold + ColabFold – – 0.321 No Hit 0.0% —
56 KP13_32201 hypothetical protein ColabFold – – 0.68 No Hit 0.0% —
57 KP13_32199 hypothetical protein AlphaFold + ColabFold – – 0.147 No Hit 0.0% —
58 KP13_32196 HTH-type transcriptional regulator MetR AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. +25 total
0.3 No Hit 0.0% —
59 KP13_32195 hypothetical protein ColabFold – – 0.797 No Hit 0.0% —
60 KP13_32194 hypothetical protein AlphaFold + ColabFold – – 0.948 No Hit 0.0% —
61 KP13_32192 RmlC-type domain-containing protein AlphaFold + ColabFold – – 0.584 No Hit 0.0% —
62 KP13_32189 inner membrane protein AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0015205Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other. +36 total
0.955 No Hit 0.0% —
63 KP13_32188 Two-component regulatory system response regulator protein AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0000160A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). +47 total
0.527 No Hit 0.0% —
64 KP13_32187 Proline porter II AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. +25 total
0.514 No Hit 0.0% —
65 KP13_32185 hypothetical protein AlphaFold + ColabFold – – 0.113 No Hit 0.0% —
66 KP13_32182 Protein hfq hfq AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003723Binding to an RNA molecule or a portion thereof. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +25 total
0.221 No Hit 0.0% —
67 KP13_32181 HTH-type transcriptional repressor NsrR nsrR AlphaFold + ColabFold –
GO:0045892Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0051537Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands. +36 total
0.227 No Hit 0.0% —
68 KP13_32179 ABC transporter periplasmic-binding protein AlphaFold + ColabFold –
GO:0030313An envelope that surrounds a bacterial cell and includes the cytoplasmic membrane and everything external, encompassing the periplasmic space, cell wall, and outer membrane if present. GO:0030246Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
0.102 No Hit 0.0% —
69 KP13_32178 hypothetical protein ColabFold – – 0.6 No Hit 0.0% —
70 KP13_32177 hypothetical protein ColabFold – – No pocket No Hit 0.0% —
71 KP13_32176 hypothetical protein ColabFold – – No pocket No Hit 0.0% —
72 KP13_32175 Peptidase PmbA pmbA AlphaFold + ColabFold –
GO:0006508The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. GO:0008237Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
0.435 No Hit 0.0% —
73 KP13_32174 PRD domain-containing protein ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
0.763 No Hit 0.0% —
74 KP13_32173 hypothetical protein ColabFold – – 0.373 No Hit 0.0% —
75 KP13_32172 hypothetical protein ColabFold – – 0.04 No Hit 0.0% —
Page of 234 · 5842 total proteins