Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 proteins

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Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
101 KP13_32138 hypothetical protein ColabFold – – 0.601 No Hit 0.0% —
102 KP13_32137 hypothetical protein AlphaFold + ColabFold – – 0.001 No Hit 0.0% —
103 KP13_32136 ATP-dependent DNA helicase subunit SbcC AlphaFold + ColabFold –
GO:0006302The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix. GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. GO:0004519Catalysis of the cleavage of ester linkages within nucleic acids by creating internal breaks. +36 total
0.524 No Hit 0.0% —
104 KP13_32133 HMP-PP phosphatase cof AlphaFold + ColabFold
3.6.1.-
GO:0016818Catalysis of the hydrolysis of any acid anhydride which contains phosphorus. GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. GO:0002145Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate + H2O = hydroxymethylpyrimidine phosphate + phosphate + H+. +25 total
0.332 No Hit 0.0% —
105 KP13_32130 hypothetical protein ColabFold – – 0.625 No Hit 0.0% —
106 KP13_32129 hypothetical protein ColabFold – – 0.392 No Hit 0.0% —
107 KP13_32127 hypothetical protein ColabFold – – 0.87 No Hit 0.0% —
108 KP13_32126 maltose-inducible porin maltoporin lamB AlphaFold + ColabFold –
GO:0009279A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures. GO:0042956The directed movement of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, across a membrane. GO:0034219The process in which a carbohydrate is transported across a membrane. +58 total
0.802 No Hit 0.0% —
109 KP13_32125 lactose operon repressor AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. +14 total
0.889 No Hit 0.0% —
110 KP13_32124 hemolysin expression-modulating protein Hha hha AlphaFold + ColabFold – – 0.374 No Hit 0.0% —
111 KP13_32122 insertion sequence IS1 ColabFold – – 0.507 No Hit 0.0% —
112 KP13_32118 DNA relaxase mbeA AlphaFold + ColabFold – – 0.553 No Hit 0.0% —
113 KP13_32116 insertion element IS1 protein insA AlphaFold + ColabFold –
GO:0006313A type of transposition in which a transposable element (transposon) is moved to another part of a genome, either by a cut-and-paste mechanism or a replicative mechanism.
0.438 No Hit 0.0% —
114 KP13_32115 hypothetical protein ColabFold – – 0.832 No Hit 0.0% —
115 KP13_32114 hypothetical protein ColabFold – – 0.62 No Hit 0.0% —
116 KP13_32113 hypothetical protein ColabFold –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
0.705 No Hit 0.0% —
117 KP13_32112 hypothetical protein ColabFold – – 0.956 No Hit 0.0% —
118 KP13_32111 putative replication initiation protein ColabFold – – 0.352 No Hit 0.0% —
119 KP13_32108 hypothetical protein ColabFold – – 0.809 No Hit 0.0% —
120 KP13_32107 hypothetical protein AlphaFold + ColabFold – – 0.247 No Hit 0.0% —
121 KP13_32105 type IV conjugative transfer system VirB1-like protein AlphaFold + ColabFold – – 0.248 No Hit 0.0% —
122 KP13_32104 hypothetical protein AlphaFold + ColabFold – – No pocket No Hit 0.0% —
123 KP13_32103 initiator RepB protein repB AlphaFold + ColabFold –
GO:0003887Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. GO:0006270The process in which DNA-dependent DNA replication is started; it begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, followed by DNA unwinding.
0.146 No Hit 0.0% —
124 KP13_32102 hypothetical protein AlphaFold + ColabFold – – 0.5 No Hit 0.0% —
125 KP13_32101 conjugal transfer TraH-like (IncFII R100) protein AlphaFold + ColabFold – – 0.356 No Hit 0.0% —
Page of 234 · 5842 total proteins