Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5192 / 5842 proteins Structure: AlphaFold

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Structure: AlphaFold ×
# Protein Description Gene Structure EC GO Metabolism Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
2401 KP13_00055 Galactonate operon transcriptional repressor dgoR AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
No map 0.588 No Hit 0.0% —
2402 KP13_03459 putative lipoprotein AlphaFold + ColabFold – – No map 0.587 No Hit 0.0% —
2403 KP13_02536 hypothetical protein AlphaFold + ColabFold – – No map 0.587 No Hit 0.0% —
2404 KP13_02363 Methionine import ATP-binding protein AlphaFold + ColabFold –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +14 total
No map 0.587 Hit 37.8% 1.16e-28
2405 KP13_01650 Ferritin-1 ftnA AlphaFold + ColabFold
1.16.3.2
GO:0008199Binding to a ferric iron ion, Fe(III). GO:0006879A homeostatic process involved in the maintenance of a steady state level of iron ions within a cell. GO:0006826The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. +47 total
No map 0.587 No Hit 0.0% —
2406 KP13_00639 hypothetical protein AlphaFold + ColabFold – – No map 0.587 No Hit 0.0% —
2407 KP13_00593 Rhamnulose-1-phosphate aldolase rhaD AlphaFold + ColabFold
4.1.2.19
GO:0008994Catalysis of the reaction: L-rhamnulose 1-phosphate = glycerone phosphate + (S)-lactaldehyde. GO:0019301The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +25 total
No map 0.587 No Hit 0.0% —
2408 KP13_06624 hypothetical protein AlphaFold + ColabFold –
GO:0009061The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor.
No map 0.586 No Hit 0.0% —
2409 KP13_04803 Type IV secretion system protein virB11 virB11 AlphaFold + ColabFold –
GO:0044097The controlled release of proteins or DNA by a cell, via the type IV secretion system. GO:0043684A complex of proteins related to those involved in bacterial DNA conjugative transfer, that permits the transfer of DNA or proteins into the extracellular milieu or directly into host cells. In general the type IV complex forms a multisubunit cell-envelope-spanning structure composed of a secretion channel and often a pilus or other surface filament or protein(s). GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. +14 total
No map 0.586 No Hit 0.0% —
2410 KP13_02789 Modulator of drug activity B mdaB AlphaFold + ColabFold
1.6.5.10
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0008753Catalysis of the reaction: NADPH + H+ + a quinone = NADP+ + a quinol.
No map 0.586 No Hit 0.0% —
2411 KP13_01813 PII uridylyl-transferase glnD AlphaFold + ColabFold –
GO:0016779Catalysis of the transfer of a nucleotidyl group from one compound (donor) to another (acceptor). GO:0008773Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII). GO:0006807OBSOLETE. The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen. +36 total
No map 0.586 No Hit 0.0% —
2412 KP13_05196 putative CoA transferase AlphaFold + ColabFold
2.8.3.8
GO:0008410Catalysis of the transfer of a coenzyme A (CoA) group from one compound (donor) to another (acceptor). GO:0046952The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA. GO:0008775Catalysis of the reaction: acyl-CoA + acetate = a fatty acid anion + acetyl-CoA.
No map 0.585 Hit 24.1% 2.26e-08
2413 KP13_04934 hypothetical protein AlphaFold + ColabFold – – No map 0.585 No Hit 0.0% —
2414 KP13_03371 Carbohydrate/purine kinase domain-containing protein AlphaFold + ColabFold –
GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0016301Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
No map 0.585 Hit 25.0% 1.35e-06
2415 KP13_00724 hypothetical protein AlphaFold + ColabFold – – No map 0.585 No Hit 0.0% —
2416 KP13_00003 Ribose operon repressor rbsR AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. +14 total
No map 0.585 No Hit 0.0% —
2417 KP13_32365 transposase for insertion sequence-like element IS431mec AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). +25 total
No map 0.584 No Hit 0.0% —
2418 KP13_32222 Transposase for insertion sequence-like element IS431mec AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
No map 0.584 No Hit 0.0% —
2419 KP13_32192 RmlC-type domain-containing protein AlphaFold + ColabFold – – No map 0.584 No Hit 0.0% —
2420 KP13_06698 transposase for insertion sequence-like element IS431mec AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
No map 0.584 No Hit 0.0% —
2421 KP13_05944 transposase for insertion sequence-like element IS431mec AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
No map 0.584 No Hit 0.0% —
2422 KP13_05451 Phage shock protein D pspD AlphaFold + ColabFold – – No map 0.584 No Hit 0.0% —
2423 KP13_04319 Glycosyl transferase, family 3 AlphaFold + ColabFold –
GO:0000162The chemical reactions and pathways resulting in the formation of L-tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; L-tryptophan is synthesized from chorismate via anthranilate. GO:0004048Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
No map 0.584 No Hit 0.0% —
2424 KP13_03958 Transposase for insertion sequence-like element IS431mec AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
No map 0.584 No Hit 0.0% —
2425 KP13_03937 Transposase for insertion sequence-like element IS431mec AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
No map 0.584 No Hit 0.0% —
Page of 208 · 5192 total proteins