Proteins

Genome: NC_002516.2

Description: Pseudomonas aeruginosa PAO1, complete genome

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Applied filters EC Number: 2.4.2.2

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EC Number: 2.4.2.2 ×
# Protein Description Gene Structure EC GO Metabolism Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
1 PA3823 queuine tRNA-ribosyltransferase PA3823, tgt AlphaFold
2.4.2.29
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0046872Binding to a metal ion. +69 total
No map 0.798 Hit 50.4% 2.91e-38
2 PA5298 xanthine phosphoribosyltransferase PA5298, xpt AlphaFold
2.4.2.22
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0000310Catalysis of the reaction: diphosphate + XMP = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine. GO:0006166Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis. +47 total
No map 0.667 No Hit N/A —
3 PA1574 hypothetical protein PA1574, ppnP Experimental + AlphaFold
2.4.2.1 2.4.2.2
GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0047975Catalysis of the reaction: guanosine + phosphate = alpha-D-ribose 1-phosphate + guanine. GO:0004731Catalysis of the reaction: purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. +36 total
No map 0.661 No Hit N/A —
4 PA1279 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase cobU, PA1279, cobT AlphaFold
2.4.2.21
GO:0008939Catalysis of the reaction: 5,6-dimethylbenzimidazole + nicotinate D-ribonucleotide = alpha-ribazole 5'-phosphate + H+ + nicotinate. GO:0009236The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
No map 0.628 No Hit N/A —
5 PA4543 hypothetical protein PA4543 AlphaFold
2.4.2.1 3.5.4.4 2.4.2.28
GO:0004000Catalysis of the reaction: adenosine + H2O = inosine + NH4+. GO:0005507Binding to a copper (Cu) ion. GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. +14 total
No map 0.201 Hit 36.1% 3.34e-10
Page 1 of 1 · 5 total proteins