Proteins

Genome: KpATCC43816

Description: Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome

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5081 proteins

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Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
1676 VK055_5080 putative mobilization protein AlphaFold + ColabFold – – 0.719 No Hit 0.0% —
1677 VK055_4307 rnfC Barrel sandwich hybrid domain protein AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0051536Binding to an iron-sulfur cluster, a combination of iron and sulfur atoms. GO:0051539Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. +25 total
0.719 No Hit 0.0% —
1678 VK055_0151 A predicted alpha-helical domain with a conserved ER motif family protein AlphaFold + ColabFold – – 0.719 No Hit 0.0% —
1679 VK055_3048 phage lambda receptor protein maltose high-affinity receptor AlphaFold + ColabFold –
GO:0015288Enables the transfer of substances, sized less than 1000 Da, from one side of a membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0015768The directed movement of maltose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the catabolism of glycogen and starch. +710 total
0.718 No Hit 0.0% —
1680 VK055_0314 acrB/AcrD/AcrF family protein AlphaFold + ColabFold –
GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. +25 total
0.718 No Hit 0.0% —
1681 VK055_3719 hypothetical protein AlphaFold + ColabFold – – 0.717 No Hit 0.0% —
1682 VK055_3056 azlC family protein AlphaFold + ColabFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:1903785The directed movement of L-valine across a membrane.
0.717 No Hit 0.0% —
1683 VK055_1626 phage holin 2 family protein AlphaFold + ColabFold –
GO:0044660The dissemination of mature viral particles from a host cell via the formation by the virus of pores in its host cell membrane.
0.717 No Hit 0.0% —
1684 VK055_0156 fatty acid desaturase family protein AlphaFold + ColabFold –
GO:0006629The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
0.717 No Hit 0.0% —
1685 VK055_5157 hypothetical protein AlphaFold + ColabFold –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.716 No Hit 0.0% —
1686 VK055_4946 aryl-phospho-beta-D-glucosidase BglH bglH AlphaFold + ColabFold –
GO:0004553Catalysis of the hydrolysis of any O-glycosyl bond. GO:0005975The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +25 total
0.716 Hit 36.8% 3.19e-11
1687 VK055_4047 hypothetical protein AlphaFold + ColabFold – – 0.716 No Hit 0.0% —
1688 VK055_3401 major Facilitator Superfamily protein AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. +47 total
0.716 No Hit 0.0% —
1689 VK055_2890 hypothetical protein AlphaFold + ColabFold – – 0.716 No Hit 0.0% —
1690 VK055_2672 sugar (and other) transporter family protein AlphaFold + ColabFold –
GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
0.716 No Hit 0.0% —
1691 VK055_1095 hypothetical protein AlphaFold + ColabFold – – 0.716 No Hit 0.0% —
1692 VK055_0881 hypothetical protein AlphaFold + ColabFold –
GO:0008270Binding to a zinc ion (Zn). GO:0003871Catalysis of the reaction: 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate. GO:0009086OBSOLETE. The chemical reactions and pathways resulting in the de novo formation of L-methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins. +14 total
0.716 No Hit 0.0% —
1693 VK055_4972 hypothetical protein AlphaFold + ColabFold – – 0.715 No Hit 0.0% —
1694 VK055_3706 fimbrial assembly family protein AlphaFold + ColabFold – – 0.715 No Hit 0.0% —
1695 VK055_1051 hypothetical protein AlphaFold + ColabFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
0.715 No Hit 0.0% —
1696 VK055_5015 putative outer membrane lipoprotein Wza wza AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0015159Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. GO:0015774The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. +47 total
0.714 No Hit 0.0% —
1697 VK055_4190 ureD urease accessory family protein AlphaFold + ColabFold –
GO:0016151Binding to a nickel (Ni) cation. GO:0006807OBSOLETE. The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen. GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
0.714 No Hit 0.0% —
1698 VK055_3958 NADH:flavin oxidoreductase / NADH oxidase familyprotein AlphaFold + ColabFold –
GO:0010181Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0008670Catalysis of the reactions: a 4,5-saturated-(2E)-enoyl-CoA + NADP+ = a (2E,4E)-dienoyl-CoA + H+ + NADPH, and a (2E,4Z)-dienoyl-CoA + H+ + NADPH = a 4,5-saturated-(2E)-enoyl-CoA + NADP+. +36 total
0.714 No Hit 0.0% —
1699 VK055_3381 hypothetical protein AlphaFold + ColabFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
0.714 No Hit 0.0% —
1700 VK055_2653 3,4-dihydroxyphenylacetate 2,3-dioxygenase hpaD AlphaFold + ColabFold –
GO:0008198Binding to a ferrous iron ion, Fe(II). GO:0006725OBSOLETE. The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells. GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. +14 total
0.714 No Hit 0.0% —
Page of 204 · 5081 total proteins