Proteins

Genome: KpATCC43816

Description: Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome

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5081 proteins

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Sorted by Human off-target (descending)

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Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
1 VK055_5191 helix-turn-helix domain of resolvase family protein ColabFold –
GO:0006310Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. GO:0000150Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.203 No Hit 0.0% —
2 VK055_5190 resolvase, N terminal domain protein AlphaFold + ColabFold –
GO:0006310Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. GO:0000150Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). +14 total
0.088 No Hit 0.0% —
3 VK055_5189 hypothetical protein AlphaFold + ColabFold –
GO:0016788Catalysis of the hydrolysis of any ester bond.
0.204 No Hit 0.0% —
4 VK055_5188 hypothetical protein ColabFold – – 0.122 No Hit 0.0% —
5 VK055_5187 hypothetical protein ColabFold – – 0.216 No Hit 0.0% —
6 VK055_5186 hypothetical protein ColabFold – – 0.618 No Hit 0.0% —
7 VK055_5185 phage tail family protein ColabFold – – 0.532 No Hit 0.0% —
8 VK055_5184 putative kinase domain protein ColabFold – – 0.949 No Hit 0.0% —
9 VK055_5183 hypothetical protein ColabFold – – 0.295 No Hit 0.0% —
10 VK055_5182 phage tail tape measure protein, lambda family AlphaFold + ColabFold – – 0.973 No Hit 0.0% —
11 VK055_5181 hypothetical protein AlphaFold + ColabFold – – 0.456 No Hit 0.0% —
12 VK055_5180 hypothetical protein AlphaFold + ColabFold – – 0.552 No Hit 0.0% —
13 VK055_5179 structural protein 3 AlphaFold + ColabFold – – 0.68 No Hit 0.0% —
14 VK055_5178 hypothetical protein ColabFold – – 0.116 No Hit 0.0% —
15 VK055_5177 hypothetical protein AlphaFold + ColabFold – – 0.101 No Hit 0.0% —
16 VK055_5176 hypothetical protein ColabFold – – 0.428 No Hit 0.0% —
17 VK055_5175 phage gp6-like head-tail connector family protein AlphaFold + ColabFold – – 0.209 No Hit 0.0% —
18 VK055_5174 phage major capsid protein, HK97 family AlphaFold + ColabFold – – 0.936 No Hit 0.0% —
19 VK055_5173 phage prohead protease, HK97 family AlphaFold + ColabFold –
GO:0008233Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid. GO:0006508The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
0.707 No Hit 0.0% —
20 VK055_5172 phage portal protein, HK97 family AlphaFold + ColabFold – – 0.85 No Hit 0.0% —
21 VK055_5171 phage Terminase family protein AlphaFold + ColabFold –
GO:0004519Catalysis of the cleavage of ester linkages within nucleic acids by creating internal breaks.
0.893 No Hit 0.0% —
22 VK055_5170 hypothetical protein ColabFold – – 0.376 No Hit 0.0% —
23 VK055_5169 hypothetical protein ColabFold – – 0.538 No Hit 0.0% —
24 VK055_5168 hypothetical protein AlphaFold + ColabFold – – 0.352 No Hit 0.0% —
25 VK055_5167 hypothetical protein ColabFold – – 0.435 No Hit 0.0% —
Page of 204 · 5081 total proteins