Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

Search, filter, and prioritize proteins.

Export view
7 / 5842 proteins

Scoring formula None

Sorted by Druggability (descending)

Applied filters GO Term: GO:0004792

Search query No active search

Rows per page 25

Rows
Active criteria 1
GO Term: GO:0004792 · Catalysis of the reaction: thiosulfate + hydrogen cyanide = thiocyanate + sulfite + 2 H+. ×
# Protein Description Gene Structure EC GO Metabolism Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
1 KP13_31983 Thiosulfate sulfurtransferase AlphaFold DB model + ColabFold model –
GO:0004792Catalysis of the reaction: thiosulfate + hydrogen cyanide = thiocyanate + sulfite + 2 H+.
No map 0.696 No Hit 0.0% —
2 KP13_04100 Inner membrane protein AlphaFold DB model + ColabFold model –
GO:0004792Catalysis of the reaction: thiosulfate + hydrogen cyanide = thiocyanate + sulfite + 2 H+.
No map 0.66 No Hit 0.0% —
3 KP13_00671 Thiosulfate sulfurtransferase glpE glpE AlphaFold DB model + ColabFold model
2.8.1.1
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0004792Catalysis of the reaction: thiosulfate + hydrogen cyanide = thiocyanate + sulfite + 2 H+. GO:0103041Catalysis of the reaction: thiosulfate + [thioredoxin]-dithiol = sulfite + 2 H+ + [thioredoxin]-disulfide + hydrogen sulfide.
No map 0.405 No Hit 0.0% —
4 KP13_00855 3-mercaptopyruvate sulfurtransferase sseA AlphaFold DB model + ColabFold model –
GO:0004792Catalysis of the reaction: thiosulfate + hydrogen cyanide = thiocyanate + sulfite + 2 H+. GO:0016783Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor). GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +14 total
No map 0.404 Hit 41.4% 1.62e-67
5 KP13_31805 Sulfur carrier protein ThiS adenylyltransferase thiF AlphaFold DB model + ColabFold model –
GO:0008641Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. +47 total
No map 0.159 Hit 41.0% 5.49e-42
6 KP13_05408 Putative thiosulfate sulfurtransferase AlphaFold DB model + ColabFold model –
GO:0016783Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor). GO:0004792Catalysis of the reaction: thiosulfate + hydrogen cyanide = thiocyanate + sulfite + 2 H+.
No map 0.142 Hit 28.4% 4.61e-19
7 KP13_04289 Sulfur carrier protein moaD adenylyltransferase moeB AlphaFold DB model + ColabFold model
2.7.7.80
GO:0008641Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond. GO:0006777The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +47 total
No map 0.13 Hit 47.9% 2.09e-07
Page 1 of 1 · 7 total proteins