Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 / 5842 proteins

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# Protein Description Gene Structure EC GO Metabolism Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
226 KP13_03991 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.082 No Hit 0.0% —
227 KP13_31795 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.082 No Hit 0.0% —
228 KP13_00654 putative N-acetyltransferase AlphaFold DB model + ColabFold model
2.3.1.-
GO:0016747Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
No map 0.083 No Hit 0.0% —
229 KP13_00871 Putative prophage CPS-53 integrase intS AlphaFold DB model + ColabFold model –
GO:0006310Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
No map 0.083 No Hit 0.0% —
230 KP13_01054 hypothetical protein ColabFold model – – No map 0.083 No Hit 0.0% —
231 KP13_04463 Putative ABC transporter periplasmic-binding protein AlphaFold DB model + ColabFold model –
GO:0015846The directed movement of polyamines, organic compounds containing two or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0019808Binding to a polyamine, an organic compound containing two or more amino groups. GO:0042597The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria). +14 total
No map 0.083 No Hit 0.0% —
232 KP13_04589 Coenzyme PQQ synthesis protein B pqqB AlphaFold DB model + ColabFold model –
GO:0018189The chemical reactions and pathways resulting in the formation of the cofactor pyrroloquinoline quinone (PQQ); it is synthesized from a small peptide containing tyrosine and glutamic acid; these amino acids in the peptide are multiply cross-linked and the rest of the peptide is removed.
No map 0.083 No Hit 0.0% —
233 KP13_01419 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.084 No Hit 0.0% —
234 KP13_04131 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.084 No Hit 0.0% —
235 KP13_02099 putative isochorismatase AlphaFold DB model + ColabFold model –
GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
No map 0.085 No Hit 0.0% —
236 KP13_04398 putative ABC transporter ATP-binding protein AlphaFold DB model + ColabFold model –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. GO:0015833The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. +25 total
No map 0.085 Hit 40.3% 1.11e-06
237 KP13_31576 Multidrug resistance protein A AlphaFold DB model + ColabFold model –
GO:1990961A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell. GO:0042910Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. +36 total
No map 0.085 No Hit 0.0% —
238 KP13_02975 p-hydroxybenzoic acid efflux pump subunit aaeA aaeA AlphaFold DB model + ColabFold model –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
No map 0.086 No Hit 0.0% —
239 KP13_03960 hypothetical protein ColabFold model – – No map 0.086 No Hit 0.0% —
240 KP13_04140 hypothetical protein AlphaFold DB model + ColabFold model –
GO:0046872Binding to a metal ion.
No map 0.086 No Hit 0.0% —
241 KP13_04863 Phosphatase nudJ nudJ AlphaFold DB model + ColabFold model
3.6.1.-
GO:0017111Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate. GO:0004787Catalysis of the reaction: thiamine diphosphate + H2O = thiamine monophosphate + phosphate. GO:0017110Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleoside monophosphate + phosphate. +14 total
No map 0.086 Hit 28.4% 3.26e-06
242 KP13_03005 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.087 No Hit 0.0% —
243 KP13_01056 hypothetical protein ColabFold model – – No map 0.088 No Hit 0.0% —
244 KP13_02377 tRNA pseudouridine synthase C truC AlphaFold DB model + ColabFold model
5.4.99.26
GO:0003723Binding to an RNA molecule or a portion thereof. GO:0001522The intramolecular conversion of uridine to pseudouridine within an RNA molecule. GO:0009451The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically. +47 total
No map 0.088 Hit 29.9% 1.35e-14
245 KP13_04026 Gp7 phage protein AlphaFold DB model + ColabFold model – – No map 0.088 No Hit 0.0% —
246 KP13_03655 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.089 No Hit 0.0% —
247 KP13_03829 Esterase AlphaFold DB model + ColabFold model –
GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
No map 0.089 No Hit 0.0% —
248 KP13_05236 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.089 No Hit 0.0% —
249 KP13_05455 putative 6-phospho-beta-glucosidase AlphaFold DB model + ColabFold model –
GO:0005975The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. GO:0004553Catalysis of the hydrolysis of any O-glycosyl bond. GO:0003824Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. +25 total
No map 0.089 No Hit 0.0% —
250 KP13_05623 DNA-binding trans-acting positive regulator mgA mgA AlphaFold DB model + ColabFold model – – No map 0.089 No Hit 0.0% —
Page of 234 · 5842 total proteins