Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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# Protein Description Gene Structure EC GO Metabolism Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
3351 KP13_03100 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.417 No Hit 0.0% —
3352 KP13_03101 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.694 No Hit 0.0% —
3353 KP13_03102 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.637 No Hit 0.0% —
3354 KP13_03104 hypothetical protein ColabFold model – – No map 0.099 No Hit 0.0% —
3355 KP13_03105 hypothetical protein ColabFold model – – No map 0.544 No Hit 0.0% —
3356 KP13_03106 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.661 No Hit 0.0% —
3357 KP13_03107 putative plasmid partitioning protein, RepA AlphaFold DB model + ColabFold model – – No map 0.455 No Hit 0.0% —
3358 KP13_03108 putative ParB-like partition protein AlphaFold DB model + ColabFold model –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
No map 0.691 No Hit 0.0% —
3359 KP13_03110 hypothetical protein ColabFold model – – No map 0.506 No Hit 0.0% —
3360 KP13_03111 putative transposase AlphaFold DB model + ColabFold model –
GO:0004803Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element. GO:0006313A type of transposition in which a transposable element (transposon) is moved to another part of a genome, either by a cut-and-paste mechanism or a replicative mechanism. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
No map 0.224 No Hit 0.0% —
3361 KP13_03112 putative transposase AlphaFold DB model + ColabFold model –
GO:0003676Binding to a nucleic acid. GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
No map 0.566 No Hit 0.0% —
3362 KP13_03113 putative periplasmic protein AlphaFold DB model + ColabFold model – – No map 0.942 No Hit 0.0% —
3363 KP13_03114 putative periplasmic protein AlphaFold DB model + ColabFold model – – No map 0.286 No Hit 0.0% —
3364 KP13_03115 putative periplasmic protein AlphaFold DB model + ColabFold model – – No map 0.038 No Hit 0.0% —
3365 KP13_03116 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.187 No Hit 0.0% —
3366 KP13_03117 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.15 No Hit 0.0% —
3367 KP13_03119 Integrase/recombinase int AlphaFold DB model + ColabFold model –
GO:0006310Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
No map 0.526 No Hit 0.0% —
3368 KP13_03124 Dihydropteroate synthase type-1 sul1 AlphaFold DB model + ColabFold model –
GO:0042558The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid. GO:0004156Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-aminobenzoate = diphosphate + dihydropteroate. GO:0009396The chemical reactions and pathways resulting in the formation of folic acid and its derivatives. +14 total
No map 0.923 No Hit 0.0% —
3369 KP13_03125 hypothetical protein AlphaFold DB model + ColabFold model – – No map No pocket No Hit 0.0% —
3370 KP13_03126 putative transposase AlphaFold DB model + ColabFold model –
GO:0004803Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element. GO:0006313A type of transposition in which a transposable element (transposon) is moved to another part of a genome, either by a cut-and-paste mechanism or a replicative mechanism. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
No map 0.402 No Hit 0.0% —
3371 KP13_03127 hypothetical protein ColabFold model – – No map 0.296 No Hit 0.0% —
3372 KP13_03128 Beta-lactamase CTX-M-2 blaCTX AlphaFold DB model + ColabFold model
3.5.2.6
GO:0008800Catalysis of the reaction: a beta-lactam + H2O = a substituted beta-amino acid. GO:0017001The chemical reactions and pathways resulting in the breakdown of antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms. GO:0046677Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms. +14 total
No map 0.513 No Hit 0.0% —
3373 KP13_03129 Quaternary ammonium compound-resistance protein qacE AlphaFold DB model + ColabFold model –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. +14 total
No map 0.32 No Hit 0.0% —
3374 KP13_03130 Dihydropteroate synthase type-1 sulI AlphaFold DB model + ColabFold model
2.5.1.15
GO:0042558The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid. GO:0004156Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-aminobenzoate = diphosphate + dihydropteroate. GO:0009396The chemical reactions and pathways resulting in the formation of folic acid and its derivatives. +58 total
No map 0.923 No Hit 0.0% —
3375 KP13_03131 IS21 family insertion protein AlphaFold DB model + ColabFold model –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. GO:0006260The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
No map 0.681 No Hit 0.0% —
Page of 234 · 5842 total proteins