Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 / 5842 proteins

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# Protein Description Gene Structure EC GO Metabolism Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
3876 KP13_03924 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.465 No Hit 0.0% —
3877 KP13_03925 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.831 No Hit 0.0% —
3878 KP13_03927 Ferrous iron permease efeU efeU AlphaFold DB model + ColabFold model –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0033573A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. +36 total
No map 0.908 No Hit 0.0% —
3879 KP13_03928 peptidase M75 family protein AlphaFold DB model + ColabFold model –
GO:0042597The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).
No map 0.483 No Hit 0.0% —
3880 KP13_03929 Peroxidase AlphaFold DB model + ColabFold model
1.11.1.-
GO:0020037Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring. GO:0004601Catalysis of the reaction: a reduced substrate + ROOH = an oxidized substrate + ROH + H2O. GO:0033212The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis. +58 total
No map 0.976 No Hit 0.0% —
3881 KP13_03934 Transcriptional regulator, LysR family ColabFold model – – No map 0.381 No Hit 0.0% —
3882 KP13_03935 HTH-type transcriptional regulator uidR uidR AlphaFold DB model + ColabFold model –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. GO:0000976Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
No map 0.711 No Hit 0.0% —
3883 KP13_03936 putative arginase protein ColabFold model –
GO:0046872Binding to a metal ion.
No map 0.659 No Hit 0.0% —
3884 KP13_03937 Transposase for insertion sequence-like element IS431mec AlphaFold DB model + ColabFold model –
GO:0003676Binding to a nucleic acid. GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
No map 0.584 No Hit 0.0% —
3885 KP13_03938 transposase insC for insertion sequence element IS2H insC4 AlphaFold DB model + ColabFold model –
GO:0004803Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element. GO:0006313A type of transposition in which a transposable element (transposon) is moved to another part of a genome, either by a cut-and-paste mechanism or a replicative mechanism. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
No map 0.403 No Hit 0.0% —
3886 KP13_03939 hypothetical protein ColabFold model – – No map 0.138 No Hit 0.0% —
3887 KP13_03940 hypothetical protein ColabFold model – – No map 0.369 No Hit 0.0% —
3888 KP13_03941 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.322 No Hit 0.0% —
3889 KP13_03942 Polymerase/histidinol phosphatase domain-containing protein AlphaFold DB model + ColabFold model – – No map 0.707 No Hit 0.0% —
3890 KP13_03943 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.628 No Hit 0.0% —
3891 KP13_03944 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.195 No Hit 0.0% —
3892 KP13_03946 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.188 No Hit 0.0% —
3893 KP13_03947 GCN5-related N-acetyltransferase (GNAT) AlphaFold DB model + ColabFold model –
GO:0016747Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor). GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:1990189Catalysis of the reaction: acetyl-CoA + N-terminal L-seryl-[protein] = CoA + H+ + N-terminal Nalpha-acetyl-L-seryl-[protein]. +14 total
No map 0.347 No Hit 0.0% —
3894 KP13_03950 Transcriptional repressor frmR frmR AlphaFold DB model + ColabFold model –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0046872Binding to a metal ion. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). +14 total
No map 0.624 No Hit 0.0% —
3895 KP13_03952 Glyoxalase/bleomycin resistance protein/dioxygenase AlphaFold DB model + ColabFold model –
GO:0051213Catalysis of the incorporation of both atoms of molecular oxygen (O2) into the substrate. GO:0016829Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
No map 0.117 No Hit 0.0% —
3896 KP13_03953 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.849 No Hit 0.0% —
3897 KP13_03955 NADH dehydrogenase-like protein AlphaFold DB model + ColabFold model
1.6.5.9
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0006116OBSOLETE. A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADH, to the oxidized form, NAD+. GO:0003954Catalysis of the reaction: NADH + H+ + acceptor = NAD+ + reduced acceptor. +14 total
No map 0.304 No Hit 0.0% —
3898 KP13_03957 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.177 No Hit 0.0% —
3899 KP13_03958 Transposase for insertion sequence-like element IS431mec AlphaFold DB model + ColabFold model –
GO:0003676Binding to a nucleic acid. GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
No map 0.584 No Hit 0.0% —
3900 KP13_03959 putative transposase AlphaFold DB model + ColabFold model – – No map 0.074 No Hit 0.0% —
Page of 234 · 5842 total proteins