Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 / 5842 proteins

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Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
401 KP13_00641 High-affinity branched-chain amino acid transport system permease protein livH livH AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. +811 total
0.548 No Hit 0.0% —
402 KP13_00642 High-affinity branched-chain amino acid transport system permease protein livM livM AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. +14 total
0.891 No Hit 0.0% —
403 KP13_00645 Phage/plasmid maintenance protein phd AlphaFold + ColabFold – – 0.276 No Hit 0.0% —
404 KP13_00646 Death on curing protein of phage P1 doc AlphaFold + ColabFold –
GO:0016301Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
0.596 No Hit 0.0% —
405 KP13_00647 sn-glycerol-3-phosphate-binding periplasmic protein ugpB ugpB AlphaFold + ColabFold –
GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
0.425 No Hit 0.0% —
406 KP13_00648 sn-glycerol-3-phosphate transport system permease protein ugpA ugpA AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
0.856 No Hit 0.0% —
407 KP13_00649 sn-glycerol-3-phosphate transport system permease protein ugpE ugpE AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
0.638 No Hit 0.0% —
408 KP13_00652 hypothetical protein AlphaFold + ColabFold – – 0.19 No Hit 0.0% —
409 KP13_00654 putative N-acetyltransferase AlphaFold + ColabFold
2.3.1.-
GO:0016747Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
0.083 No Hit 0.0% —
410 KP13_00655 hypothetical protein AlphaFold + ColabFold – – 0.651 No Hit 0.0% —
411 KP13_00658 HTH-type transcriptional regulator gntR gntR AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +25 total
0.297 No Hit 0.0% —
412 KP13_00660 Low-affinity gluconate transporter gntU AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0015128Enables the transfer of gluconate from one side of a membrane to the other. Gluconate is the aldonic acid derived from glucose. GO:0035429The process in which gluconate is transported across a membrane. Gluconate is the aldonic acid derived from glucose. +14 total
0.888 No Hit 0.0% —
413 KP13_00661 hypothetical protein AlphaFold + ColabFold – – 0.848 No Hit 0.0% —
414 KP13_00662 Aspartate-semialdehyde dehydrogenase asd AlphaFold + ColabFold –
GO:0009089OBSOLETE. The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate. GO:0009086OBSOLETE. The chemical reactions and pathways resulting in the de novo formation of L-methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins. GO:0009097OBSOLETE. The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid. +811 total
0.538 No Hit 0.0% —
415 KP13_00664 Glycogen debranching enzyme glgX AlphaFold + ColabFold
3.2.1.196
GO:0005980The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues. GO:0005975The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. GO:0004553Catalysis of the hydrolysis of any O-glycosyl bond. +36 total
0.651 No Hit 0.0% —
416 KP13_00666 Glycogen synthase glgA AlphaFold + ColabFold
2.4.1.21
GO:0004373Catalysis of the reaction: [(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-alpha-D-glucosyl](n+1) + H+ + UDP. GO:0016757Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor). GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +25 total
0.56 No Hit 0.0% —
417 KP13_00668 hypothetical protein AlphaFold + ColabFold – – 0.352 No Hit 0.0% —
418 KP13_00669 putative HTH-type transcriptional regulator AlphaFold + ColabFold –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.651 No Hit 0.0% —
419 KP13_00671 Thiosulfate sulfurtransferase glpE glpE AlphaFold + ColabFold
2.8.1.1
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0004792Catalysis of the reaction: thiosulfate + hydrogen cyanide = thiocyanate + sulfite + 2 H+. GO:0103041Catalysis of the reaction: thiosulfate + [thioredoxin]-dithiol = sulfite + 2 H+ + [thioredoxin]-disulfide + hydrogen sulfide.
0.405 No Hit 0.0% —
420 KP13_00672 Rhomboid protease glpG glpG AlphaFold + ColabFold
3.4.21.105
GO:0006508The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0004252Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). +14 total
0.922 No Hit 0.0% —
421 KP13_00673 Glycerol-3-phosphate regulon repressor glpR AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
0.287 No Hit 0.0% —
422 KP13_00674 HTH-type transcriptional regulator malT AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0005515Binding to a protein. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). +47 total
0.239 No Hit 0.0% —
423 KP13_00675 hypothetical protein ColabFold – – 0.489 No Hit 0.0% —
424 KP13_00677 4-alpha-glucanotransferase malQ AlphaFold + ColabFold
2.4.1.25
GO:0005975The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. GO:0004134Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1->4)-alpha-D-glucan.
0.484 No Hit 0.0% —
425 KP13_00678 High-affinity gluconate transporter gntT AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0015128Enables the transfer of gluconate from one side of a membrane to the other. Gluconate is the aldonic acid derived from glucose. GO:0035429The process in which gluconate is transported across a membrane. Gluconate is the aldonic acid derived from glucose. +14 total
0.749 No Hit 0.0% —
Page of 234 · 5842 total proteins