Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 / 5842 proteins

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# Protein Description Gene Structure EC GO Metabolism Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
4501 KP13_04776 Nitrogen assimilation regulatory protein nac nac AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). +14 total
No map 0.386 No Hit 0.0% —
4502 KP13_04777 HTH-type transcriptional regulator cbl cbl AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. GO:0000976Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon. +14 total
No map 0.929 No Hit 0.0% —
4503 KP13_04778 hypothetical protein AlphaFold + ColabFold –
GO:0016740Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. GO:0005576The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. GO:0042597The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria). +58 total
No map 0.268 No Hit 0.0% —
4504 KP13_04779 hypothetical protein AlphaFold + ColabFold – – No map 0.352 No Hit 0.0% —
4505 KP13_04780 hypothetical protein AlphaFold + ColabFold – – No map 0.496 No Hit 0.0% —
4506 KP13_04781 LysR family transcriptional regulator AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. GO:0043565Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. +14 total
No map 0.623 No Hit 0.0% —
4507 KP13_04783 hypothetical protein ColabFold – – No map 0.011 No Hit 0.0% —
4508 KP13_04784 hypothetical protein ColabFold – – No map 0.402 No Hit 0.0% —
4509 KP13_04786 hypothetical protein AlphaFold + ColabFold –
GO:0016779Catalysis of the transfer of a nucleotidyl group from one compound (donor) to another (acceptor). GO:0051607Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
No map 0.315 No Hit 0.0% —
4510 KP13_04787 hypothetical protein ColabFold – – No map 0.725 No Hit 0.0% —
4511 KP13_04789 hypothetical protein AlphaFold + ColabFold –
GO:0140701Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(3'-5')A-P(3'-5') (cyclic 3',3' GAMP). GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0005525Binding to GTP, guanosine triphosphate. +36 total
No map 0.961 No Hit 0.0% —
4512 KP13_04790 NAD(P)-binding domain-containing protein AlphaFold + ColabFold –
GO:0008641Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond. GO:0016779Catalysis of the transfer of a nucleotidyl group from one compound (donor) to another (acceptor). GO:0061503Catalysis of the ATP-dependent dehydration of t6A to form cyclic t6A. +14 total
No map 0.147 No Hit 0.0% —
4513 KP13_04791 hypothetical protein AlphaFold + ColabFold –
GO:0046872Binding to a metal ion. GO:0008237Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. GO:0006508The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
No map 0.177 No Hit 0.0% —
4514 KP13_04792 hypothetical protein ColabFold – – No map 0.828 No Hit 0.0% —
4515 KP13_04793 hypothetical protein ColabFold – – No map 0.004 No Hit 0.0% —
4516 KP13_04794 hypothetical protein ColabFold – – No map 0.177 No Hit 0.0% —
4517 KP13_04795 hypothetical protein ColabFold – – No map 0.486 No Hit 0.0% —
4518 KP13_04796 hypothetical protein ColabFold – – No map 0.61 No Hit 0.0% —
4519 KP13_04797 antirestriction protein ColabFold –
GO:0003697Binding to single-stranded DNA.
No map 0.742 No Hit 0.0% —
4520 KP13_04798 putative MobC mobilization protein ColabFold – – No map 0.048 No Hit 0.0% —
4521 KP13_04799 putative MobB mobilization protein AlphaFold + ColabFold – – No map 0.642 No Hit 0.0% —
4522 KP13_04800 hypothetical protein AlphaFold + ColabFold – – No map 0.37 No Hit 0.0% —
4523 KP13_04801 hypothetical protein AlphaFold + ColabFold – – No map 0.248 No Hit 0.0% —
4524 KP13_04802 hypothetical protein AlphaFold + ColabFold – – No map 0.468 No Hit 0.0% —
4525 KP13_04803 Type IV secretion system protein virB11 virB11 AlphaFold + ColabFold –
GO:0044097The controlled release of proteins or DNA by a cell, via the type IV secretion system. GO:0043684A complex of proteins related to those involved in bacterial DNA conjugative transfer, that permits the transfer of DNA or proteins into the extracellular milieu or directly into host cells. In general the type IV complex forms a multisubunit cell-envelope-spanning structure composed of a secretion channel and often a pilus or other surface filament or protein(s). GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. +14 total
No map 0.586 No Hit 0.0% —
Page of 234 · 5842 total proteins