Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 proteins

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# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
5476 KP13_31748 Ferrous iron transport protein A feoA Experimental + ColabFold –
GO:0046914Binding to a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
0.318 No Hit 0.0% —
5477 KP13_31750 RelE family toxin-antitoxin system protein ColabFold – – 0.899 No Hit 0.0% —
5478 KP13_31751 hypothetical protein ColabFold – – 0.356 No Hit 0.0% —
5479 KP13_31752 hypothetical protein ColabFold – – 0.315 No Hit 0.0% —
5480 KP13_31753 hypothetical protein ColabFold – – 0.248 No Hit 0.0% —
5481 KP13_31756 sodium/glutamate symporter gltS AlphaFold + ColabFold –
GO:0015501Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glutamate(out) + Na+(out) = glutamate(in) + Na+(in). GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0015813The directed movement of L-glutamate across a membrane by means of some agent such as a transporter or a pore. +14 total
0.803 No Hit 0.0% —
5482 KP13_31757 hypothetical protein ColabFold – – 0.258 No Hit 0.0% —
5483 KP13_31758 hypothetical protein ColabFold – – 0.55 No Hit 0.0% —
5484 KP13_31760 putative lipoprotein AlphaFold + ColabFold – – 0.333 No Hit 0.0% —
5485 KP13_31761 biotin sulfoxide reductase bisC AlphaFold + ColabFold –
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0043546Binding to a molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands. GO:0030288The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall. +36 total
0.958 No Hit 0.0% —
5486 KP13_31763 Insertion element IS1 protein insA AlphaFold + ColabFold –
GO:0006313A type of transposition in which a transposable element (transposon) is moved to another part of a genome, either by a cut-and-paste mechanism or a replicative mechanism.
0.438 No Hit 0.0% —
5487 KP13_31764 hypothetical protein AlphaFold + ColabFold – – 0.311 No Hit 0.0% —
5488 KP13_31767 hypothetical protein ColabFold – – 0.147 No Hit 0.0% —
5489 KP13_31768 hypothetical protein ColabFold – – 0.424 No Hit 0.0% —
5490 KP13_31769 chloride channel protein AlphaFold + ColabFold – – 0.313 No Hit 0.0% —
5491 KP13_31770 intracellular growth attenuator protein IgaA igaA Experimental + AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
0.876 No Hit 0.0% —
5492 KP13_31775 Acriflavine resistance protein E acrE AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
0.913 No Hit 0.0% —
5493 KP13_31777 hypothetical protein AlphaFold + ColabFold – – 0.443 No Hit 0.0% —
5494 KP13_31778 arginine repressor argR AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0006525The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. +25 total
0.395 No Hit 0.0% —
5495 KP13_31779 Oxaloacetate decarboxylase beta chain AlphaFold + ColabFold
7.2.4.2
GO:0016829Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring. GO:0006814The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +14 total
0.824 No Hit 0.0% —
5496 KP13_31780 hypothetical protein ColabFold – – 0.881 No Hit 0.0% —
5497 KP13_31781 hypothetical protein ColabFold – – 0.591 No Hit 0.0% —
5498 KP13_31782 putative phospholipid ABC transporter-binding protein mlaD mlaD AlphaFold + ColabFold –
GO:0015914The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester. GO:0005543Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester. GO:0005548OBSOLETE. Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester.
0.201 No Hit 0.0% —
5499 KP13_31783 hypothetical protein AlphaFold + ColabFold – – 0.146 No Hit 0.0% —
5500 KP13_31784 hypothetical protein ColabFold – – 0.428 No Hit 0.0% —
Page of 234 · 5842 total proteins