Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 proteins

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# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
5601 KP13_31934 capsule synthesis regulatory protein B ColabFold – – 0.63 No Hit 0.0% —
5602 KP13_31937 hypothetical protein AlphaFold + ColabFold – – 0.829 No Hit 0.0% —
5603 KP13_31938 hypothetical protein AlphaFold + ColabFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
0.697 No Hit 0.0% —
5604 KP13_31939 Electron transport complex protein rnfC rnfC AlphaFold + ColabFold
7.-.-.-
GO:0009055A molecular function representing the directed movement of electrons from one molecular entity to another, typically mediated by electron carriers or acceptors, resulting in the transfer of energy and/or the reduction-oxidation (redox) transformation of chemical species. This activity is fundamental to various biological processes, including cellular respiration and photosynthesis, as well as numerous enzymatic reactions involved in metabolic pathways. GO:0051539Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. +36 total
0.643 No Hit 0.0% —
5605 KP13_31940 Formate acetyltransferase pfl AlphaFold + ColabFold
2.3.1.54
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0008861Catalysis of the reaction: acetyl-CoA + formate = CoA + pyruvate. GO:0003824Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. +36 total
0.536 No Hit 0.0% —
5606 KP13_31941 Lipid II flippase FtsW ftsW AlphaFold + ColabFold
2.4.99.28
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0009252The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls and consisting of long glycan strands of alternating residues of beta-(1,4) linked N-acetylglucosamine and N-acetylmuramic acid, cross-linked by short peptides. GO:0051301The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. +710 total
0.996 No Hit 0.0% —
5607 KP13_31945 hypothetical protein AlphaFold + ColabFold – – 0.119 No Hit 0.0% —
5608 KP13_31946 putative transcription regulator AlphaFold + ColabFold –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.97 No Hit 0.0% —
5609 KP13_31949 hypothetical protein AlphaFold + ColabFold – – 0.138 No Hit 0.0% —
5610 KP13_31951 hypothetical protein ColabFold – – 0.551 No Hit 0.0% —
5611 KP13_31952 putative transposase AlphaFold + ColabFold –
GO:0043565Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
0.223 No Hit 0.0% —
5612 KP13_31953 hypothetical protein ColabFold – – 0.795 No Hit 0.0% —
5613 KP13_31954 hypothetical protein ColabFold – – No pocket No Hit 0.0% —
5614 KP13_31956 putative HTH-type transcription regulator AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.802 No Hit 0.0% —
5615 KP13_31957 hypothetical protein ColabFold – – 0.513 No Hit 0.0% —
5616 KP13_31958 putative reverse transcriptase AlphaFold + ColabFold – – 0.062 No Hit 0.0% —
5617 KP13_31959 diguanylate cyclase domain-containing protein AlphaFold + ColabFold –
GO:0005515Binding to a protein.
0.644 No Hit 0.0% —
5618 KP13_31960 hypothetical protein AlphaFold + ColabFold – – 0.264 No Hit 0.0% —
5619 KP13_31961 hypothetical protein AlphaFold + ColabFold – – 0.419 No Hit 0.0% —
5620 KP13_31962 hypothetical protein ColabFold – – 0.579 No Hit 0.0% —
5621 KP13_31963 hypothetical protein ColabFold – – 0.955 No Hit 0.0% —
5622 KP13_31964 hypothetical protein ColabFold – – 0.993 No Hit 0.0% —
5623 KP13_31966 hypothetical protein ColabFold – – 0.78 No Hit 0.0% —
5624 KP13_31967 hypothetical protein ColabFold – – 0.501 No Hit 0.0% —
5625 KP13_31968 HNH endonuclease domain-containing protein AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0008270Binding to a zinc ion (Zn). GO:0004519Catalysis of the cleavage of ester linkages within nucleic acids by creating internal breaks. +25 total
0.092 No Hit 0.0% —
Page of 234 · 5842 total proteins