KEGG:map00260

Glycine, serine and threonine metabolism

KpATCC43816 - Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome

All pathways Protein ranking
Reactions 29
Proteins 35
Metabolites 58
Chokepoints 5

Pathway map

Reaction-to-metabolite flow reconstructed from the imported SBML participants.

Chokepoint reaction Metabolite ⇌ Reversible reaction Currency metabolites hidden
Computing layout…

Connected pathways

Other pathways in this genome that share reactions with this one.

MODEL Unassigned metabolic reactions 65 shared KEGG Glyoxylate and dicarboxylate metabolism 9 shared KEGG Glycolysis / Gluconeogenesis 8 shared KEGG One carbon pool by folate 6 shared KEGG Methane metabolism 5 shared KEGG Aminoacyl-tRNA biosynthesis 5 shared KEGG Glycerophospholipid metabolism 4 shared KEGG Pentose phosphate pathway 4 shared KEGG Purine metabolism 4 shared KEGG Pyrimidine metabolism 3 shared KEGG Glycerolipid metabolism 3 shared KEGG Cysteine and methionine metabolism 2 shared KEGG Phenylalanine, tyrosine and tryptophan biosynthesis 2 shared KEGG Pantothenate and CoA biosynthesis 2 shared KEGG Monobactam biosynthesis 2 shared KEGG Phenylalanine metabolism 2 shared KEGG Biosynthesis of various nucleotide sugars 2 shared KEGG Propanoate metabolism 1 shared KEGG Valine, leucine and isoleucine biosynthesis 1 shared KEGG Arginine biosynthesis 1 shared KEGG Pyruvate metabolism 1 shared KEGG beta-Alanine metabolism 1 shared KEGG Phosphonate and phosphinate metabolism 1 shared KEGG Tryptophan metabolism 1 shared KEGG Thiamine metabolism 1 shared KEGG Alanine, aspartate and glutamate metabolism 1 shared

Reaction table

Catalyzed reactions, mapped genes, and SBML substrates/products.

AKBLIG-RXN

EC 2.3.1.29 · R00371 · AKBLIG-RXN · reversible

acetyl-CoA glycine
⇌
L-2-amino-3-oxobutanoate coenzyme A
VK055_3509

AMACETOXID-RXN

EC 1.4.3.21 · R02529 · AMACETOXID-RXN · not reversible

consuming
aminoacetone H2O dioxygen
→
methylglyoxal ammonium hydrogen peroxide
VK055_1043

BADH-RXN

EC 1.2.1.8 · R02565 · BADH-RXN · not reversible

betaine aldehyde H2O NAD+
→
glycine betaine H+ NADH
VK055_1952

CHD-RXN

EC 1.1.99.1 · R01025 · CHD-RXN · reversible

an oxidized electron carrier choline
⇌
a reduced two electron carrier betaine aldehyde
VK055_1953

GCVP-RXN

EC 1.4.4.2 · R03425 · GCVP-RXN · reversible

a [glycine-cleavage complex H protein] N6-[(R)-lipoyl]-L-lysine glycine H+
⇌
a [glycine-cleavage complex H protein] N6-aminomethyldihydrolipoyl-L-lysine CO2
VK055_4143 VK055_4144

GCVT-RXN

EC 2.1.2.10 · R04125 · GCVT-RXN · reversible

a [glycine-cleavage complex H protein] N6-aminomethyldihydrolipoyl-L-lysine a tetrahydrofolate
⇌
a 5,10-methylenetetrahydrofolate a [glycine-cleavage complex H protein] N6-dihydrolipoyl-L-lysine ammonium
VK055_4142 VK055_4143

GLYOHMETRANS-RXN

EC 2.1.2.1 · R00945 · GLYOHMETRANS-RXN · reversible

a 5,10-methylenetetrahydrofolate glycine H2O
⇌
L-serine a tetrahydrofolate
VK055_4625

PGLYCDEHYDROG-RXN

EC 1.1.1.95 · R01513 · PGLYCDEHYDROG-RXN · reversible

3-phospho-D-glycerate NAD+
⇌
3-phosphooxypyruvate H+ NADH
No mapped protein

R101-RXN

EC 2.6.1.76 · R06977 · R101-RXN · reversible

2-oxoglutarate L-2,4-diaminobutanoate
⇌
L-aspartate 4-semialdehyde L-glutamate
VK055_0687

SARCOX-RXN

EC 1.5.3.1 · R00610 · SARCOX-RXN · not reversible

consuming
sarcosine H2O dioxygen
→
formaldehyde glycine hydrogen peroxide
VK055_1395

THREOSPON-RXN

EC - · R03758 · THREOSPON-RXN · not reversible

L-2-amino-3-oxobutanoate H+
→
aminoacetone CO2
No mapped protein

THRESYN-RXN

EC 4.2.3.1 · R01466 · THRESYN-RXN · not reversible

consuming
O-phospho-L-homoserine H2O
→
L-threonine phosphate
VK055_2570

TRYPSYN-RXN

EC 4.2.1.20 · R02722 · TRYPSYN-RXN · not reversible

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate L-serine
→
D-glyceraldehyde 3-phosphate L-tryptophan H2O
VK055_1196 VK055_1197