Proteins

Genome: KpATCC43816

Description: Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome

Search, filter, and prioritize proteins.

Export view
5081 proteins

Scoring formula None

Sorted by Druggability (descending)

Applied filters No active filters

Search query No active search

Rows per page 25

Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
5001 VK055_1003 hypothetical protein AlphaFold + ColabFold – – 0.019 No Hit 0.0% —
5002 VK055_0733 putative transposase AlphaFold + ColabFold –
GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome. GO:0003676Binding to a nucleic acid.
0.019 No Hit 0.0% —
5003 VK055_3019 hypothetical protein AlphaFold + ColabFold – – 0.018 No Hit 0.0% —
5004 VK055_0743 acetyltransferase family protein AlphaFold + ColabFold –
GO:0016747Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
0.018 No Hit 0.0% —
5005 VK055_3111 ribosomal protein L7/L12 rplL AlphaFold + ColabFold –
GO:0003735The action of a molecule that contributes to the structural integrity of the ribosome. GO:0006412The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. GO:0005840An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins. +25 total
0.017 Hit 38.7% 7.16e-06
5006 VK055_0381 CRISPR type I-E/ECOLI-associated protein CasB/Cse2 casB AlphaFold + ColabFold – – 0.017 No Hit 0.0% —
5007 VK055_4569 16S rRNA processing protein RimM rimM AlphaFold + ColabFold –
GO:0006364Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. GO:0043022Binding to a ribosome. GO:0005840An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins. +25 total
0.016 No Hit 0.0% —
5008 VK055_4537 fimbrial family protein AlphaFold + ColabFold –
GO:0007155The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. GO:0009289A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter. GO:0043709The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species.
0.016 No Hit 0.0% —
5009 VK055_4641 iron-sulfur cluster assembly protein iscA AlphaFold + ColabFold –
GO:0016226The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster. GO:0051536Binding to an iron-sulfur cluster, a combination of iron and sulfur atoms. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +25 total
0.014 Hit 54.8% 7.79e-07
5010 VK055_3353 putative phosphopantetheinyl transferase AlphaFold + ColabFold –
GO:0008897Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form. GO:0000287Binding to a magnesium (Mg) ion.
0.014 No Hit 0.0% —
5011 VK055_0587 glutathione S-transferase, N-terminal domain protein AlphaFold + ColabFold – – 0.014 No Hit 0.0% —
5012 VK055_0366 hypothetical protein AlphaFold + ColabFold – – 0.014 No Hit 0.0% —
5013 VK055_4809 cell division protein DedD AlphaFold + ColabFold –
GO:0032506A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells). GO:0030428A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells. GO:0042834Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls. +25 total
0.012 No Hit 0.0% —
5014 VK055_4675 hypothetical protein ColabFold – – 0.011 No Hit 0.0% —
5015 VK055_1697 hypothetical protein AlphaFold + ColabFold –
GO:0042597The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).
0.011 No Hit 0.0% —
5016 VK055_1827 ybfN-like lipofamily protein AlphaFold + ColabFold – – 0.009 No Hit 0.0% —
5017 VK055_0809 hypothetical protein AlphaFold + ColabFold – – 0.009 No Hit 0.0% —
5018 VK055_4227 minor fimbrial subunit, D-mannose specific adhesin fimH2 Experimental + ColabFold –
GO:0007155The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. GO:0009289A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter. GO:0043709The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species.
0.008 No Hit 0.0% —
5019 VK055_2745 hypothetical protein ColabFold – – 0.008 No Hit 0.0% —
5020 VK055_0758 metallo-beta-lactamase superfamily protein ColabFold – – 0.008 No Hit 0.0% —
5021 VK055_0575 putative lipoprotein AlphaFold + ColabFold – – 0.008 No Hit 0.0% —
5022 VK055_3140 magnesium-dependent DNase AlphaFold + ColabFold
3.1.11.- 3.1.13.-
GO:0016788Catalysis of the hydrolysis of any ester bond. GO:0008408Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +36 total
0.007 Hit 36.4% 3.35e-14
5023 VK055_1915 iron-containing alcohol dehydrogenase family protein AlphaFold + ColabFold –
GO:0016614Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0046872Binding to a metal ion.
0.007 No Hit 0.0% —
5024 VK055_0462 hypothetical protein AlphaFold + ColabFold – – 0.007 No Hit 0.0% —
5025 VK055_1786 hypothetical protein AlphaFold + ColabFold – – 0.006 No Hit 0.0% —
Page of 204 · 5081 total proteins