Proteins

Genome: KpATCC43816

Description: Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome

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# Protein Description Gene Structure EC GO Metabolism Druggability (P2Rank) P2RANK ligandability score for the best pocket in the experimental structure (0–1). Higher values indicate higher predicted ligandability. Available only for genomes analyzed with the curated pipeline. Druggability (FPocket) FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
5026 VK055_3027 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.002 0.128 No Hit 0.0% —
5027 VK055_2934 fxsA cytoplasmic membrane family protein AlphaFold DB model + ColabFold model –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
No map 0.002 0.945 No Hit 0.0% —
5028 VK055_2932 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.002 0.694 No Hit 0.0% —
5029 VK055_2361 putative-tRNA hydrolase domain protein AlphaFold DB model + ColabFold model
3.1.1.29
GO:0006415The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code). GO:0003747Involved in catalyzing the release of a nascent polypeptide chain from a ribosome. GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. +47 total
No map 0.002 0.212 No Hit 0.0% —
5030 VK055_2105 acrA Membrane Fusion Protein acrA AlphaFold DB model + ColabFold model –
GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. +47 total
No map 0.002 0.448 No Hit 0.0% —
5031 VK055_2096 DNA-binding protein, YbaB/EbfC family AlphaFold DB model + ColabFold model –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0043590The region of a bacterial cell to which the DNA is confined. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
No map 0.002 0.328 No Hit 0.0% —
5032 VK055_1975 hypothetical protein ColabFold model – – No map 0.002 0.542 No Hit 0.0% —
5033 VK055_1688 stationary phase nucleoid protein that sequesters iron and protects DNA from damage dps AlphaFold DB model + ColabFold model
1.16.-.-
GO:0016722Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered. GO:0008199Binding to a ferric iron ion, Fe(III). GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. +47 total
No map 0.002 0.725 No Hit 0.0% —
5034 VK055_1545 integration host factor, beta subunit ihfB AlphaFold DB model + ColabFold model –
GO:0006310Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0030527The action of a molecule that contributes to the structural integrity of chromatin. +47 total
No map 0.002 0.367 No Hit 0.0% —
5035 VK055_1390 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.002 0.585 No Hit 0.0% —
5036 VK055_1288 hypothetical protein AlphaFold DB model + ColabFold model – – No map N/A 0.002 No Hit 0.0% —
5037 VK055_0999 ydfZ family protein AlphaFold DB model + ColabFold model – – No map N/A 0.002 No Hit 0.0% —
5038 VK055_0933 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.002 No pocket No Hit 0.0% —
5039 VK055_0840 putative prolyl endopeptidase AlphaFold DB model + ColabFold model – – No map 0.002 0.564 No Hit 0.0% —
5040 VK055_4322 BMC domain protein AlphaFold DB model + ColabFold model –
GO:0031469An organelle found in bacteria consisting of a proteinaceous coat containing metabolic enzymes whose purpose is the sequestration or concentration of metabolites and which has the appearance of a polygonal granule by electron microscopy.
No map 0.001 0.532 No Hit 0.0% —
5041 VK055_2756 hypothetical protein ColabFold model – – No map 0.001 0.407 No Hit 0.0% —
5042 VK055_1854 hypothetical protein ColabFold model – – No map 0.001 0.387 No Hit 0.0% —
5043 VK055_1659 biofilm formation family protein AlphaFold DB model + ColabFold model – – No map 0.001 0.34 No Hit 0.0% —
5044 VK055_1556 hypothetical protein AlphaFold DB model + ColabFold model – – No map N/A 0.001 No Hit 0.0% —
5045 VK055_1354 protein involved in stress resistance and biofilm formation ycfR AlphaFold DB model + ColabFold model – – No map N/A 0.001 No Hit 0.0% —
5046 VK055_1164 hypothetical protein AlphaFold DB model + ColabFold model – – No map N/A 0.001 No Hit 0.0% —
5047 VK055_0872 marB family protein marB AlphaFold DB model + ColabFold model – – No map N/A 0.001 No Hit 0.0% —
5048 VK055_0439 efflux transporter, RND family, MFP subunit AlphaFold DB model + ColabFold model –
GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. +25 total
No map 0.001 0.99 No Hit 0.0% —
5049 VK055_0225 hypothetical protein AlphaFold DB model + ColabFold model – – No map N/A 0.001 No Hit 0.0% —
5050 VK055_4840 nuoE nuoE AlphaFold DB model + ColabFold model –
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0051537Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands. GO:0046872Binding to a metal ion. +25 total
No map 0.000 0.506 Hit 35.0% 6.27e-27
Page of 204 · 5081 total proteins