Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 proteins

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# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
226 KP13_31959 diguanylate cyclase domain-containing protein AlphaFold + ColabFold –
GO:0005515Binding to a protein.
0.644 No Hit 0.0% —
227 KP13_31958 putative reverse transcriptase AlphaFold + ColabFold – – 0.062 No Hit 0.0% —
228 KP13_31957 hypothetical protein ColabFold – – 0.513 No Hit 0.0% —
229 KP13_31956 putative HTH-type transcription regulator AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.802 No Hit 0.0% —
230 KP13_31954 hypothetical protein ColabFold – – No pocket No Hit 0.0% —
231 KP13_31953 hypothetical protein ColabFold – – 0.795 No Hit 0.0% —
232 KP13_31952 putative transposase AlphaFold + ColabFold –
GO:0043565Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
0.223 No Hit 0.0% —
233 KP13_31951 hypothetical protein ColabFold – – 0.551 No Hit 0.0% —
234 KP13_31949 hypothetical protein AlphaFold + ColabFold – – 0.138 No Hit 0.0% —
235 KP13_31946 putative transcription regulator AlphaFold + ColabFold –
GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.97 No Hit 0.0% —
236 KP13_31945 hypothetical protein AlphaFold + ColabFold – – 0.119 No Hit 0.0% —
237 KP13_31941 Lipid II flippase FtsW ftsW AlphaFold + ColabFold
2.4.99.28
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0009252The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls and consisting of long glycan strands of alternating residues of beta-(1,4) linked N-acetylglucosamine and N-acetylmuramic acid, cross-linked by short peptides. GO:0051301The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. +710 total
0.996 No Hit 0.0% —
238 KP13_31940 Formate acetyltransferase pfl AlphaFold + ColabFold
2.3.1.54
GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0008861Catalysis of the reaction: acetyl-CoA + formate = CoA + pyruvate. GO:0003824Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. +36 total
0.536 No Hit 0.0% —
239 KP13_31939 Electron transport complex protein rnfC rnfC AlphaFold + ColabFold
7.-.-.-
GO:0009055A molecular function representing the directed movement of electrons from one molecular entity to another, typically mediated by electron carriers or acceptors, resulting in the transfer of energy and/or the reduction-oxidation (redox) transformation of chemical species. This activity is fundamental to various biological processes, including cellular respiration and photosynthesis, as well as numerous enzymatic reactions involved in metabolic pathways. GO:0051539Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. +36 total
0.643 No Hit 0.0% —
240 KP13_31938 hypothetical protein AlphaFold + ColabFold –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
0.697 No Hit 0.0% —
241 KP13_31937 hypothetical protein AlphaFold + ColabFold – – 0.829 No Hit 0.0% —
242 KP13_31934 capsule synthesis regulatory protein B ColabFold – – 0.63 No Hit 0.0% —
243 KP13_31933 Protein dsrB dsrB AlphaFold + ColabFold – – 0.122 No Hit 0.0% —
244 KP13_31932 hypothetical protein AlphaFold + ColabFold – – 0.856 No Hit 0.0% —
245 KP13_31931 hypothetical protein AlphaFold + ColabFold – – 0.87 No Hit 0.0% —
246 KP13_31930 transposase insD for insertion element IS2I AlphaFold + ColabFold –
GO:0003676Binding to a nucleic acid. GO:0015074The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
0.178 No Hit 0.0% —
247 KP13_31929 putative transposase AlphaFold + ColabFold –
GO:0004803Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element. GO:0006313A type of transposition in which a transposable element (transposon) is moved to another part of a genome, either by a cut-and-paste mechanism or a replicative mechanism. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
0.329 No Hit 0.0% —
248 KP13_31924 Glutathione-binding protein gsiB AlphaFold + ColabFold –
GO:0043190A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0030288The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall. +25 total
0.733 No Hit 0.0% —
249 KP13_31923 Putative ABC transporter arginine-binding protein 2 artI AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0071705The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0030288The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall. +25 total
0.07 No Hit 0.0% —
250 KP13_31922 EvpB family type VI secretion protein AlphaFold + ColabFold – – 0.217 No Hit 0.0% —
Page of 234 · 5842 total proteins