Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 / 5842 proteins

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# Protein Description Gene Structure EC GO Metabolism Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
3701 KP13_03645 Putative arabinogalactan oligomer transport system permease protein ganQ ganQ AlphaFold DB model + ColabFold model –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +25 total
No map 0.648 No Hit 0.0% —
3702 KP13_03646 Putative arabinogalactan oligomer transport system permease protein ganP ganP AlphaFold DB model + ColabFold model –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:1990060Protein complex facilitating ATP-dependent maltose transport through inner cell membrane (periplasm to cytoplasm) in Gram-negative bacteria. In E. coli the system is composed of a periplasmic maltose-binding protein (MBP), two integral membrane proteins, MalF and MalG, and two copies of the cytoplasmic ATP-binding cassette MalK. +25 total
No map 0.545 No Hit 0.0% —
3703 KP13_03647 Cyclodextrin-binding protein cycB AlphaFold DB model + ColabFold model –
GO:0008643The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y. GO:0015144Enables the transfer of carbohydrate from one side of a membrane to the other. GO:0055052A complex for the transport of metabolites into the cell, consisting of 5 subunits: two ATP-binding subunits, two membrane spanning subunits, and one substrate-binding subunit. In organisms with two membranes, the substrate-binding protein moves freely in the periplasmic space and joins the other subunits only when bound with substrate. In organisms with only one membrane the substrate-binding protein is tethered to the cytoplasmic membrane and associated with the other subunits. Transport of the substrate across the membrane is driven by the hydrolysis of ATP. +47 total
No map 0.892 No Hit 0.0% —
3704 KP13_03649 hypothetical protein ColabFold model – – No map 0.176 No Hit 0.0% —
3705 KP13_03650 EAL domain-containing protein AlphaFold DB model + ColabFold model
3.1.4.52
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0071111Catalysis of the reaction: cyclic di-3',5'-guanylate + H2O = 5'-phosphoguanylyl(3'->5')guanosine + H+.
No map 0.763 No Hit 0.0% —
3706 KP13_03651 hypothetical protein AlphaFold DB model + ColabFold model –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0046872Binding to a metal ion. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
No map 0.956 No Hit 0.0% —
3707 KP13_03652 Nickel/cobalt efflux system rcnA rcnA AlphaFold DB model + ColabFold model –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0035444The directed movement of nickel (Ni) cations across a membrane by means of some agent such as a transporter or pore. GO:0015099Enables the transfer of nickel (Ni) cations from one side of a membrane to the other. +47 total
No map 0.912 No Hit 0.0% —
3708 KP13_03653 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.905 No Hit 0.0% —
3709 KP13_03655 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.089 No Hit 0.0% —
3710 KP13_03656 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.513 No Hit 0.0% —
3711 KP13_03657 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.178 No Hit 0.0% —
3712 KP13_03662 Nitrogen regulatory protein P-II 2 glnK AlphaFold DB model + ColabFold model –
GO:0030234A molecular function regulator that modulates a catalytic activity. GO:0006808Any process that modulates the frequency, rate or extent of nitrogen utilization. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +14 total
No map 0.258 No Hit 0.0% —
3713 KP13_03665 putative HTH-type transcriptional regulator AlphaFold DB model + ColabFold model –
GO:0043565Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. +14 total
No map 0.284 No Hit 0.0% —
3714 KP13_03670 Long-chain acyl-CoA thioesterase FadM fadM AlphaFold DB model + ColabFold model –
GO:0016787Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. GO:0047617Catalysis of the reaction: a fatty acyl-CoA + H2O = a fatty acid + CoA + H+.
No map 0.714 No Hit 0.0% —
3715 KP13_03672 Peptidyl-prolyl cis-trans isomerase D ppiD AlphaFold DB model + ColabFold model –
GO:0003755Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0). GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
No map 0.513 No Hit 0.0% —
3716 KP13_03673 DNA-binding protein HU-beta hupB AlphaFold DB model + ColabFold model –
GO:0030527The action of a molecule that contributes to the structural integrity of chromatin. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +69 total
No map 0.404 No Hit 0.0% —
3717 KP13_03678 Trigger factor tig AlphaFold DB model + ColabFold model
5.2.1.8
GO:0015031The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0003755Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0). GO:0006457The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure. +69 total
No map 0.77 No Hit 0.0% —
3718 KP13_03679 hypothetical protein ColabFold model – – No map 0.492 No Hit 0.0% —
3719 KP13_03681 putative lipoprotein AlphaFold DB model + ColabFold model – – No map 0.294 No Hit 0.0% —
3720 KP13_03683 Ubiquinol oxidase subunit 2 cyoA AlphaFold DB model + ColabFold model –
GO:0022900A process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors. GO:0016682Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces oxygen. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. +58 total
No map 0.468 No Hit 0.0% —
3721 KP13_03688 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.515 No Hit 0.0% —
3722 KP13_03689 hypothetical protein AlphaFold DB model + ColabFold model –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. +14 total
No map 0.654 No Hit 0.0% —
3723 KP13_03692 3-oxosteroid 1-dehydrogenase ksdD AlphaFold DB model + ColabFold model –
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0008202The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
No map 0.466 No Hit 0.0% —
3724 KP13_03694 hypothetical protein AlphaFold DB model + ColabFold model –
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0008202The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
No map 1 No Hit 0.0% —
3725 KP13_03695 Xylose isomerase-like TIM barrel AlphaFold DB model + ColabFold model –
GO:0016853Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
No map 0.359 No Hit 0.0% —
Page of 234 · 5842 total proteins