Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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5842 / 5842 proteins

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# Protein Description Gene Structure EC GO Metabolism Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
701 KP13_05669 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.489 No Hit 0.0% —
702 KP13_05663 Putative NAD(P)H nitroreductase Experimental + ColabFold model –
GO:0016491Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
No map 0.872 No Hit 0.0% —
703 KP13_05662 Protease 4 sppA AlphaFold DB model + ColabFold model –
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0006465OBSOLETE. The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell. GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. +36 total
No map 0.492 No Hit 0.0% —
704 KP13_05660 Pyrazinamidase/nicotinamidase pncA AlphaFold DB model + ColabFold model
3.5.1.19
GO:0046872Binding to a metal ion. GO:0008936Catalysis of the reaction: nicotinamide + H2O = nicotinate + NH4+. GO:0019363The chemical reactions and pathways resulting in the formation of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.
No map 0.45 No Hit 0.0% —
705 KP13_05658 HNH endonuclease domain-containing protein AlphaFold DB model + ColabFold model –
GO:0003676Binding to a nucleic acid. GO:0008270Binding to a zinc ion (Zn). GO:0004519Catalysis of the cleavage of ester linkages within nucleic acids by creating internal breaks.
No map 0.227 No Hit 0.0% —
706 KP13_05657 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.449 No Hit 0.0% —
707 KP13_05655 Pullulanase secretion protein pulS pulS Experimental + AlphaFold DB model + ColabFold model –
GO:0006886The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
No map 0.542 No Hit 0.0% —
708 KP13_05649 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.366 No Hit 0.0% —
709 KP13_05648 Phosphotransferase system EIIB/cysteine AlphaFold DB model + ColabFold model –
GO:0009401The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC. GO:0008982Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sugar(out) = protein histidine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +36 total
No map 0.504 No Hit 0.0% —
710 KP13_05646 hypothetical protein ColabFold model – – No map 0.071 No Hit 0.0% —
711 KP13_05645 hypothetical protein ColabFold model – – No map 0.503 No Hit 0.0% —
712 KP13_05643 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.383 No Hit 0.0% —
713 KP13_05642 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.576 No Hit 0.0% —
714 KP13_05640 DNA-invertase gin ColabFold model –
GO:0000150Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA. GO:0006310Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. GO:0003677Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
No map 0.782 No Hit 0.0% —
715 KP13_05639 hypothetical protein ColabFold model – – No map 0.506 No Hit 0.0% —
716 KP13_05638 hypothetical protein ColabFold model – – No map 0.883 No Hit 0.0% —
717 KP13_05637 hypothetical protein ColabFold model – – No map 0.54 No Hit 0.0% —
718 KP13_05635 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.318 No Hit 0.0% —
719 KP13_05634 hypothetical protein ColabFold model – – No map 0.997 No Hit 0.0% —
720 KP13_05632 Transcriptional repressor protein, KorB AlphaFold DB model + ColabFold model –
GO:0005694A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. GO:0007059The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. GO:0045881Any process that activates or increases the frequency, rate or extent of sporulation.
No map 0.22 No Hit 0.0% —
721 KP13_05630 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.49 No Hit 0.0% —
722 KP13_05629 hypothetical protein ColabFold model – – No map 0.261 No Hit 0.0% —
723 KP13_05628 Site-specific DNA-methyltransferase (cytosine-N4-specific) AlphaFold DB model + ColabFold model
2.1.1.-
GO:0090124OBSOLETE. The covalent transfer of a methyl group to N-4 of cytosine in a DNA molecule. GO:0006306OBSOLETE. The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine. GO:0008170Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule. +47 total
No map 0.434 No Hit 0.0% —
724 KP13_05627 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.294 No Hit 0.0% —
725 KP13_05626 hypothetical protein AlphaFold DB model + ColabFold model – – No map 0.312 No Hit 0.0% —
Page of 234 · 5842 total proteins